Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXL17
  • Mouse genes Fbxl17
  • Rat genes Fbxl17
  • Zfish genes fbxl17
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxl17

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXL17	IPI	UniProtKB:Q9UMX1	Human	PMID:24035498
Molecular Function	GO:0005515	protein binding	FBXL17	IPI	UniProtKB:Q9UMX1	Human	PMID:27234298
Cellular Component	GO:0005737	cytoplasm	FBXL17	IDA		Human	PMID:24035498
Cellular Component	GO:0005654	nucleoplasm	FBXL17	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FBXL17	IDA		Human	PMID:24035498
Cellular Component	GO:0005634	nucleus	FBXL17	IDA		Human	PMID:27234298
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXL17	IDA		Human	PMID:24035498
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	FBXL17	IDA		Human	PMID:30190310
Biological Process	GO:0000209	protein polyubiquitination	FBXL17	IDA		Human	PMID:27234298
Biological Process	GO:0006515	protein quality control for misfolded or incompletely synthesized proteins	FBXL17	IDA		Human	PMID:30190310
Biological Process	GO:0016567	protein ubiquitination	FBXL17	IDA		Human	PMID:24035498
Biological Process	GO:0016567	protein ubiquitination	FBXL17	IDA		Human	PMID:30190310
Biological Process	GO:0008589	regulation of smoothened signaling pathway	FBXL17	IMP		Human	PMID:27234298
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL17	IDA		Human	PMID:24035498
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL17	IDA		Human	PMID:27234298

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern