Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO32
  • Mouse genes Fbxo32
  • Rat genes Fbxo32
  • Zfish genes fbxo32
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo32

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXO32	IPI	UniProtKB:O00303	Human	PMID:18354498
Molecular Function	GO:0005515	protein binding	Fbxo32	IPI	UniProtKB:Q14896	Mouse	PMID:19850579
Cellular Component	GO:0005737	cytoplasm	FBXO32	IDA		Human	PMID:26768247
Cellular Component	GO:0005737	cytoplasm	fbxo32	IDA		Zfish	PMID:26840306
Cellular Component	GO:0005829	cytosol	FBXO32	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FBXO32	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Fbxo32	IDA		Mouse	PMID:21611832
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXO32	IDA		Human	PMID:26753747
Cellular Component	GO:0030018	Z disc	Fbxo32	IDA		Mouse	PMID:19850579
Biological Process	GO:0006914	autophagy	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-1	Zfish	PMID:26840306
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-2	Zfish	PMID:26840306
Biological Process	GO:0055008	cardiac muscle tissue morphogenesis	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-1	Zfish	PMID:26840306
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Fbxo32	IDA		Mouse	PMID:23752591
Biological Process	GO:0060047	heart contraction	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-1	Zfish	PMID:26840306
Biological Process	GO:0008345	larval locomotory behavior	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-1	Zfish	PMID:26840306
Biological Process	GO:0014889	muscle atrophy	Fbxo32	IDA		Rat	PMID:11679633|RGD:633893
Biological Process	GO:0046716	muscle cell cellular homeostasis	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-2	Zfish	PMID:26840306
Biological Process	GO:0060415	muscle tissue morphogenesis	fbxo32	IMP	ZFIN:ZDB-MRPHLNO-160408-1	Zfish	PMID:26840306
Biological Process	GO:0010614	negative regulation of cardiac muscle hypertrophy	Fbxo32	IMP		Rat	PMID:24117217|RGD:11079185
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	Fbxo32	IGI	UniProtKB:G3V6Z4	Rat	PMID:24117217|RGD:11079185
Biological Process	GO:0010666	positive regulation of cardiac muscle cell apoptotic process	Fbxo32	IGI	UniProtKB:O88498	Rat	PMID:24117217|RGD:11079185
Biological Process	GO:0016567	protein ubiquitination	FBXO32	IDA		Human	PMID:26753747
Biological Process	GO:0014894	response to denervation involved in regulation of muscle adaptation	Fbxo32	IDA		Mouse	MGI:MGI:5508727|PMID:21465538
Biological Process	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation	Fbxo32	IDA		Rat	PMID:21465538|RGD:8553783

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern