Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO45
  • Mouse genes Fbxo45
  • Rat genes Fbxo45
  • Zfish genes fbxo45
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo45

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXO45	IPI	UniProtKB:O15350	Human	PMID:19581926
Molecular Function	GO:0005515	protein binding	Fbxo45	IPI	UniProtKB:P63208|UniProtKB:Q4KUS2	Mouse	MGI:MGI:4452423|PMID:19996097
Molecular Function	GO:0005515	protein binding	Fbxo45	IPI	PR:Q7TPH6	Mouse	PMID:19398581
Molecular Function	GO:0005515	protein binding	Fbxo45	IPI	PR:Q9WTX5	Mouse	PMID:19398581
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FBXO45	IDA		Human	PMID:29997255
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo45	IDA		Mouse	PMID:19996097
Cellular Component	GO:0098978	glutamatergic synapse	Fbxo45	IMP		Mouse	PMID:19996097
Cellular Component	GO:0099524	postsynaptic cytosol	Fbxo45	IDA		Mouse	PMID:19996097
Cellular Component	GO:0014069	postsynaptic density	Fbxo45	IDA		Mouse	MGI:MGI:4452423|PMID:19996097
Cellular Component	GO:0098793	presynapse	Fbxo45	IDA		Mouse	PMID:19996097
Cellular Component	GO:0099523	presynaptic cytosol	Fbxo45	IDA		Mouse	PMID:19996097
Cellular Component	GO:0045202	synapse	Fbxo45	IDA		Mouse	MGI:MGI:4452423|PMID:19996097
Biological Process	GO:0021960	anterior commissure morphogenesis	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0021800	cerebral cortex tangential migration	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0021957	corticospinal tract morphogenesis	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0006974	DNA damage response	FBXO45	IDA		Human	PMID:19581926
Biological Process	GO:0060384	innervation	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0001764	neuron migration	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Fbxo45	IDA		Mouse	MGI:MGI:4452423|PMID:19996097
Biological Process	GO:0070936	protein K48-linked ubiquitination	FBXO45	IDA		Human	PMID:29997255
Biological Process	GO:0016567	protein ubiquitination	FBXO45	IDA		Human	PMID:19581926
Biological Process	GO:0016567	protein ubiquitination	Fbxo45	IDA		Mouse	MGI:MGI:4452423|PMID:19996097
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Fbxo45	IMP		Mouse	PMID:19996097
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Fbxo45	IDA		Mouse	PMID:19996097
Biological Process	GO:0060386	synapse assembly involved in innervation	Fbxo45	IMP	MGI:MGI:3849742	Mouse	PMID:19398581
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	FBXO45	IDA		Human	PMID:19581926

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern