Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO7
  • Mouse genes Fbxo7
  • Rat genes Fbxo7
  • Zfish genes fbxo7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q15398	Human	PMID:15145941
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:16278047
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:O14980	Human	PMID:21378169
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:21378169
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:22632967
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:O60260	Human	PMID:23933751
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q9BXM7	Human	PMID:23933751
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q12933	Human	PMID:25029497
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P61289	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P25788	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P63208	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FBXO7	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0046982	protein heterodimerization activity	FBXO7	IPI	UniProtKB:Q92530	Human	PMID:18495667
Molecular Function	GO:0019901	protein kinase binding	FBXO7	IPI	UniProtKB:Q00534	Human	PMID:18495667
Molecular Function	GO:0019901	protein kinase binding	Fbxo7	IPI	PR:Q64261	Mouse	PMID:21652635
Molecular Function	GO:0043130	ubiquitin binding	FBXO7	IDA		Human	PMID:25029497
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FBXO7	IDA		Human	PMID:15145941
Molecular Function	GO:1990756	ubiquitin ligase-substrate adaptor activity	FBXO7	IDA		Human	PMID:36646384
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FBXO7	IPI	UniProtKB:Q13490	Human	PMID:16510124
Cellular Component	GO:0097414	classical Lewy body	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:0005737	cytoplasm	FBXO7	IDA		Human	PMID:16510124
Cellular Component	GO:0005737	cytoplasm	FBXO7	IDA		Human	PMID:21347293
Cellular Component	GO:0005737	cytoplasm	FBXO7	IDA		Human	PMID:21378169
Cellular Component	GO:0005737	cytoplasm	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:0005737	cytoplasm	FBXO7	IDA		Human	PMID:25029497
Cellular Component	GO:0005829	cytosol	FBXO7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	FBXO7	IDA		Human	PMID:18495667
Cellular Component	GO:0005829	cytosol	FBXO7	IDA		Human	PMID:23933751
Cellular Component	GO:0097409	glial cytoplasmic inclusion	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:1990037	Lewy body core	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:1990038	Lewy body corona	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:0097462	Lewy neurite	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:0005739	mitochondrion	FBXO7	IDA		Human	PMID:23933751
Cellular Component	GO:0005739	mitochondrion	FBXO7	IDA		Human	PMID:26310625
Cellular Component	GO:0005739	mitochondrion	Fbxo7	IDA		Mouse	MGI:MGI:5697238|PMID:26310625
Cellular Component	GO:0005654	nucleoplasm	FBXO7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:36646384
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:16510124
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:18495667
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:21347293
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:21378169
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:23656991
Cellular Component	GO:0005634	nucleus	FBXO7	IDA		Human	PMID:25029497
Cellular Component	GO:0005634	nucleus	Fbxo7	IDA		Mouse	MGI:MGI:5697238|PMID:26310625
Cellular Component	GO:0032991	protein-containing complex	FBXO7	IDA		Human	GO_REF:0000054
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXO7	IDA		Human	PMID:15145941
Cellular Component	GO:0000151	ubiquitin ligase complex	FBXO7	IDA		Human	PMID:23933751
Biological Process	GO:0000422	autophagy of mitochondrion	FBXO7	IMP		Human	PMID:23933751
Biological Process	GO:0030098	lymphocyte differentiation	Fbxo7	IGI	MGI:MGI:95407	Mouse	PMID:21652635
Biological Process	GO:0030098	lymphocyte differentiation	Fbxo7	IMP	MGI:MGI:4434927	Mouse	PMID:21652635
Biological Process	GO:0050881	musculoskeletal movement	fbxo7	IMP	ZFIN:ZDB-MRPHLNO-121218-1	Zfish	PMID:23133663
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Fbxo7	IMP		Mouse	PMID:21652635
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Fbxo7	IMP		Mouse	PMID:21652635
Biological Process	GO:0045620	negative regulation of lymphocyte differentiation	Fbxo7	IMP	MGI:MGI:4434927	Mouse	PMID:21652635
Biological Process	GO:0045620	negative regulation of lymphocyte differentiation	Fbxo7	IGI	MGI:MGI:95407	Mouse	PMID:21652635
Biological Process	GO:1901215	negative regulation of neuron death	Fbxo7	IMP		Rat	PMID:26310625|RGD:11536096
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	FBXO7	IMP		Human	PMID:25029497
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	FBXO7	IDA		Human	PMID:26310625
Biological Process	GO:1903599	positive regulation of autophagy of mitochondrion	Fbxo7	IMP		Rat	PMID:26310625|RGD:11536096
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	FBXO7	IDA		Human	PMID:36646384
Biological Process	GO:0070936	protein K48-linked ubiquitination	FBXO7	IDA		Human	PMID:36646384
Biological Process	GO:0006626	protein targeting to mitochondrion	FBXO7	IMP		Human	PMID:23933751
Biological Process	GO:0016567	protein ubiquitination	FBXO7	IDA		Human	PMID:16510124
Biological Process	GO:0016567	protein ubiquitination	FBXO7	IMP		Human	PMID:23933751
Biological Process	GO:0040012	regulation of locomotion	FBXO7	IDA		Human	PMID:26310625
Biological Process	GO:0010975	regulation of neuron projection development	FBXO7	IMP		Human	PMID:25029497
Biological Process	GO:0031647	regulation of protein stability	FBXO7	IDA		Human	PMID:15145941
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	FBXO7	IDA		Human	PMID:25029497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern