Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXW11
  • Mouse genes Fbxw11
  • Rat genes Fbxw11
  • Zfish genes fbxw11a,fbxw11b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxw11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P25963	Human	PMID:12482991
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P17181	Human	PMID:14532120
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P25963	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P30291	Human	PMID:15070733
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:15070733
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:O15534	Human	PMID:15917222
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:O70361	Human	PMID:15917222
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P19474	Human	PMID:16880511
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q9HAW4	Human	PMID:16885022
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P35222	Human	PMID:17510365
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:17510365
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q5JTC6	Human	PMID:17510365
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13127	Human	PMID:18354482
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13616	Human	PMID:18354482
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13127	Human	PMID:18354483
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:19159283
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13616	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q96K76	Human	PMID:19966869
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P25963	Human	PMID:20347421
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:20347421
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q00987	Human	PMID:20708156
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13616	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q60793	Human	PMID:22307056
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:O15169	Human	PMID:22682247
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P35222	Human	PMID:22682247
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P30291	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13616	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P32314	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P35222	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q13616	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q3KP66	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	FBXW11	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Fbxw11	IPI	UniProtKB:Q9WTX5|UniProtKB:Q9Z1E3	Mouse	MGI:MGI:2176150|PMID:11896578
Molecular Function	GO:0005515	protein binding	Fbxw11	IPI	UniProtKB:Q9Z301	Mouse	MGI:MGI:4844267|PMID:18782782
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Fbxw11	IDA		Mouse	PMID:11896578
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Fbxw11	IDA		Mouse	MGI:MGI:2176150|PMID:11896578
Cellular Component	GO:0005813	centrosome	FBXW11	IDA		Human	PMID:21399614
Cellular Component	GO:0005737	cytoplasm	Fbxw11	IDA		Mouse	MGI:MGI:5705222|PMID:18929646
Cellular Component	GO:0005737	cytoplasm	Fbxw11	IDA		Mouse	MGI:MGI:2176150|PMID:11896578
Cellular Component	GO:0005829	cytosol	Fbxw11	IDA		Mouse	MGI:MGI:4844267|PMID:18782782
Cellular Component	GO:0005634	nucleus	Fbxw11	IDA		Mouse	MGI:MGI:4844267|PMID:18782782
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXW11	IDA		Human	PMID:16880511
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXW11	IDA		Human	PMID:20347421
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Fbxw11	IDA		Mouse	MGI:MGI:2176150|PMID:11896578
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FBXW11	IMP		Human	PMID:19966869
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Fbxw11	IMP		Mouse	MGI:MGI:2176150|PMID:11896578
Biological Process	GO:0042753	positive regulation of circadian rhythm	Fbxw11	IMP		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fbxw11	IMP		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0045862	positive regulation of proteolysis	FBXW11	IMP		Human	PMID:16885022
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	FBXW11	IDA		Human	PMID:20347421
Biological Process	GO:0006470	protein dephosphorylation	Fbxw11	IDA		Mouse	MGI:MGI:4844267|PMID:18782782
Biological Process	GO:0031648	protein destabilization	FBXW11	IMP		Human	PMID:16885022
Biological Process	GO:0000209	protein polyubiquitination	FBXW11	IDA		Human	PMID:20347421
Biological Process	GO:0000209	protein polyubiquitination	Fbxw11	IDA		Mouse	MGI:MGI:2176150|PMID:11896578
Biological Process	GO:0016567	protein ubiquitination	FBXW11	IDA		Human	PMID:16885022
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXW11	IDA		Human	PMID:20347421
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxw11	IMP		Mouse	MGI:MGI:2176150|PMID:11896578
Biological Process	GO:0002040	sprouting angiogenesis	fbxw11a	IGI	ZFIN:ZDB-MRPHLNO-120725-4,ZFIN:ZDB-MRPHLNO-120725-5	Zfish	PMID:22711876
Biological Process	GO:0002040	sprouting angiogenesis	fbxw11a	IGI	ZFIN:ZDB-MRPHLNO-120725-6,ZFIN:ZDB-MRPHLNO-120725-7	Zfish	PMID:22711876
Biological Process	GO:0002040	sprouting angiogenesis	fbxw11b	IGI	ZFIN:ZDB-MRPHLNO-120725-6,ZFIN:ZDB-MRPHLNO-120725-7	Zfish	PMID:22711876
Biological Process	GO:0002040	sprouting angiogenesis	fbxw11b	IGI	ZFIN:ZDB-MRPHLNO-120725-4,ZFIN:ZDB-MRPHLNO-120725-5	Zfish	PMID:22711876

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern