Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXW5
  • Mouse genes Fbxw5
  • Rat genes Fbxw5
  • Zfish genes fbxw5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxw5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P63208	Human	PMID:15070733
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P49815	Human	PMID:18381890
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q92574	Human	PMID:18381890
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P63208	Human	PMID:19159283
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q12834	Human	PMID:21725316
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q6UVJ0	Human	PMID:21725316
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P63208	Human	PMID:22632967
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P14373	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q6UY14-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q9BYQ2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:P98095	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q2TAL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q9BYQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXW5	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fbxw5	IPI	UniProtKB:Q08509	Mouse	MGI:MGI:5476881|PMID:23314863
Molecular Function	GO:0005515	protein binding	Fbxw5	IPI	UniProtKB:Q8K288	Mouse	MGI:MGI:5582156|PMID:21600655
Molecular Function	GO:0005515	protein binding	Fbxw5	IPI	UniProtKB:Q9WTX5	Mouse	MGI:MGI:5476881|PMID:23314863
Molecular Function	GO:0019901	protein kinase binding	FBXW5	IPI	UniProtKB:O00444	Human	PMID:21725316
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	FBXW5	IDA		Human	PMID:18381890
Cellular Component	GO:0005737	cytoplasm	FBXW5	IDA		Human	PMID:21725316
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXW5	IDA		Human	PMID:21725316
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Fbxw5	IDA		Mouse	MGI:MGI:5476881|PMID:23314863
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	FBXW5	IDA		Human	PMID:18381890
Biological Process	GO:0016567	protein ubiquitination	FBXW5	IDA		Human	PMID:18381890
Biological Process	GO:0016567	protein ubiquitination	FBXW5	IDA		Human	PMID:21725316
Biological Process	GO:0016567	protein ubiquitination	Fbxw5	IDA		Mouse	MGI:MGI:5476881|PMID:23314863
Biological Process	GO:0010824	regulation of centrosome duplication	FBXW5	IMP		Human	PMID:21725316
Biological Process	GO:0007088	regulation of mitotic nuclear division	Fbxw5	IDA		Mouse	MGI:MGI:5476881|PMID:23314863
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXW5	IDA		Human	PMID:21725316
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxw5	IDA		Mouse	MGI:MGI:5476881|PMID:23314863

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern