Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0030332 | cyclin binding | FBXW7 | IDA | Human | PMID:12628165 | |
Molecular Function | GO:0030332 | cyclin binding | FBXW7 | IPI | UniProtKB:P24864 | Human | PMID:17434132 |
Molecular Function | GO:0042802 | identical protein binding | FBXW7 | IPI | UniProtKB:Q969H0 | Human | PMID:21620836 |
Molecular Function | GO:0042802 | identical protein binding | FBXW7 | IPI | UniProtKB:Q969H0 | Human | PMID:23791182 |
Molecular Function | GO:0050816 | phosphothreonine residue binding | FBXW7 | IDA | Human | PMID:17434132 | |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208 | Human | PMID:15070733 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:15103331 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:17157259 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:17314511 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P46531 | Human | PMID:17909182 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q91LX9 | Human | PMID:17909182 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208-1 | Human | PMID:19412162 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208-1 | Human | PMID:20596027 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P46531 | Human | PMID:20823234 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q13616 | Human | PMID:21145461 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208 | Human | PMID:21620836 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q9Z0Z7 | Human | PMID:22307056 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P46531 | Human | PMID:23022380 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q13616 | Human | PMID:23108047 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q16204 | Human | PMID:23108047 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:23791182 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208 | Human | PMID:23791182 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:A1L167 | Human | PMID:24000165 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q9H4H8 | Human | PMID:24344117 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P46531 | Human | PMID:25344755 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P46531 | Human | PMID:27229929 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P20393 | Human | PMID:27238018 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q3UV55 | Human | PMID:27238018 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P05412 | Human | PMID:27458189 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q8TB68 | Human | PMID:27458189 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P04198 | Human | PMID:27837025 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q8WUJ0 | Human | PMID:27880917 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:28007894 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P63208 | Human | PMID:28007894 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q8WUJ0 | Human | PMID:28007894 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:Q13616 | Human | PMID:28514442 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P62877,UniProtKB:P63208,UniProtKB:Q04721,UniProtKB:Q13616 | Human | PMID:29149593 |
Molecular Function | GO:0005515 | protein binding | FBXW7 | IPI | UniProtKB:P01106 | Human | PMID:35140242 |
Molecular Function | GO:0005515 | protein binding | Fbxw7 | IPI | UniProtKB:Q61985:PRO_0000076448 | Mouse | MGI:MGI:6107392|PMID:21953459 |
Molecular Function | GO:0005515 | protein binding | Fbxw7 | IPI | UniProtKB:O60260 | Mouse | MGI:MGI:5543313|PMID:23858059 |
Molecular Function | GO:0005515 | protein binding | Fbxw7 | IPI | PR:Q61937 | Mouse | PMID:18625840 |
Molecular Function | GO:0005515 | protein binding | Fbxw7 | IPI | PR:Q01705 | Mouse | PMID:11425854 |
Molecular Function | GO:0030674 | protein-macromolecule adaptor activity | FBXW7 | IDA | Human | PMID:12628165 | |
Molecular Function | GO:0031625 | ubiquitin protein ligase binding | FBXW7 | IPI | UniProtKB:O60260 | Human | PMID:12628165 |
Molecular Function | GO:0031625 | ubiquitin protein ligase binding | FBXW7 | IPI | UniProtKB:Q9WVS6 | Human | PMID:12628165 |
Molecular Function | GO:0097027 | ubiquitin-protein transferase activator activity | FBXW7 | IDA | Human | PMID:12628165 | |
Cellular Component | GO:0005737 | cytoplasm | FBXW7 | IDA | Human | PMID:23858059 | |
Cellular Component | GO:0005783 | endoplasmic reticulum | Fbxw7 | IDA | Mouse | PMID:11735228 | |
Cellular Component | GO:0005794 | Golgi apparatus | Fbxw7 | IDA | Mouse | PMID:11735228 | |
Cellular Component | GO:0005739 | mitochondrion | Fbxw7 | IDA | Mouse | MGI:MGI:5543313|PMID:23858059 | |
Cellular Component | GO:0005730 | nucleolus | Fbxw7 | IDA | Mouse | PMID:18625840 | |
Cellular Component | GO:0005634 | nucleus | Fbxw7 | IDA | Mouse | MGI:MGI:4887523|PMID:20208556 | |
Cellular Component | GO:0005634 | nucleus | Fbxw7 | IDA | Mouse | PMID:18625840 | |
Cellular Component | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex | FBXW7 | IPI | UniProtKB:O60260 | Human | PMID:12628165 |
Cellular Component | GO:0048471 | perinuclear region of cytoplasm | Fbxw7 | IDA | Mouse | MGI:MGI:4887523|PMID:20208556 | |
Cellular Component | GO:0019005 | SCF ubiquitin ligase complex | FBXW7 | IDA | Human | PMID:12628165 | |
Cellular Component | GO:0019005 | SCF ubiquitin ligase complex | FBXW7 | IDA | Human | PMID:15103331 | |
Cellular Component | GO:0019005 | SCF ubiquitin ligase complex | FBXW7 | IDA | Human | PMID:17434132 | |
Biological Process | GO:0001525 | angiogenesis | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-121101-1 | Zfish | PMID:22848434 |
Biological Process | GO:0001525 | angiogenesis | fbxw7 | IGI | ZFIN:ZDB-MRPHLNO-141105-1,ZFIN:ZDB-MRPHLNO-141105-4 | Zfish | PMID:23507969 |
Biological Process | GO:0001525 | angiogenesis | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-141105-1 | Zfish | PMID:23507969 |
Biological Process | GO:0001525 | angiogenesis | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-121115-4 | Zfish | PMID:22848434 |
Biological Process | GO:0001525 | angiogenesis | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-141105-3 | Zfish | PMID:23507969 |
Biological Process | GO:0030324 | lung development | Fbxw7 | IMP | MGI:MGI:5007620 | Mouse | PMID:21503901 |
Biological Process | GO:0010629 | negative regulation of gene expression | FBXW7 | IGI | RNAcentral:URS00001CC379_9606 | Human | PMID:23823476 |
Biological Process | GO:0010629 | negative regulation of gene expression | FBXW7 | IMP | Human | PMID:23823476 | |
Biological Process | GO:0031642 | negative regulation of myelination | fbxw7 | IMP | ZFIN:ZDB-GENO-160714-17 | Zfish | PMID:26538655 |
Biological Process | GO:0045746 | negative regulation of Notch signaling pathway | fbxw7 | IMP | ZFIN:ZDB-GENO-120820-1 | Zfish | PMID:22554084 |
Biological Process | GO:0045746 | negative regulation of Notch signaling pathway | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-120814-3 | Zfish | PMID:22554084 |
Biological Process | GO:2001205 | negative regulation of osteoclast development | FBXW7 | IMP | Human | PMID:29149593 | |
Biological Process | GO:2001205 | negative regulation of osteoclast development | Fbxw7 | IMP | Mouse | MGI:MGI:6106664|PMID:29149593 | |
Biological Process | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | Fbxw7 | IDA | Mouse | PMID:18625840 | |
Biological Process | GO:0007219 | Notch signaling pathway | Fbxw7 | IDA | Mouse | PMID:11425854 | |
Biological Process | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity | FBXW7 | IDA | Human | PMID:20208556 | |
Biological Process | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | FBXW7 | IMP | Human | PMID:20208556 | |
Biological Process | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | FBXW7 | IDA | Human | PMID:23858059 | |
Biological Process | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | Fbxw7 | IMP | Mouse | MGI:MGI:5543313|PMID:23858059 | |
Biological Process | GO:1901800 | positive regulation of proteasomal protein catabolic process | FBXW7 | IDA | Human | PMID:23858059 | |
Biological Process | GO:1901800 | positive regulation of proteasomal protein catabolic process | Fbxw7 | IMP | Mouse | MGI:MGI:5543313|PMID:23858059 | |
Biological Process | GO:1903955 | positive regulation of protein targeting to mitochondrion | FBXW7 | IMP | Human | PMID:24912190 | |
Biological Process | GO:0031398 | positive regulation of protein ubiquitination | FBXW7 | IDA | Human | PMID:12628165 | |
Biological Process | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | FBXW7 | IDA | Human | PMID:20208556 | |
Biological Process | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | FBXW7 | IMP | Human | PMID:27238018 | |
Biological Process | GO:2000060 | positive regulation of ubiquitin-dependent protein catabolic process | Fbxw7 | IMP | Mouse | MGI:MGI:6282935|PMID:27238018 | |
Biological Process | GO:0051443 | positive regulation of ubiquitin-protein transferase activity | FBXW7 | IDA | Human | PMID:12628165 | |
Biological Process | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | FBXW7 | IMP | Human | PMID:35395208 | |
Biological Process | GO:0031648 | protein destabilization | Fbxw7 | IDA | Mouse | PMID:18625840 | |
Biological Process | GO:0050821 | protein stabilization | FBXW7 | IDA | Human | PMID:20208556 | |
Biological Process | GO:0016567 | protein ubiquitination | FBXW7 | IDA | Human | PMID:12354302 | |
Biological Process | GO:0016567 | protein ubiquitination | FBXW7 | IDA | Human | PMID:15103331 | |
Biological Process | GO:1903146 | regulation of autophagy of mitochondrion | FBXW7 | IMP | Human | PMID:24912190 | |
Biological Process | GO:0090049 | regulation of cell migration involved in sprouting angiogenesis | Fbxw7 | IMP | Mouse | MGI:MGI:5619435|PMID:23507969 | |
Biological Process | GO:0042752 | regulation of circadian rhythm | FBXW7 | IMP | Human | PMID:27238018 | |
Biological Process | GO:0042752 | regulation of circadian rhythm | Fbxw7 | IMP | Mouse | MGI:MGI:6282935|PMID:27238018 | |
Biological Process | GO:0031641 | regulation of myelination | fbxw7 | IMP | ZFIN:ZDB-GENO-180802-25 | Zfish | PMID:28855284 |
Biological Process | GO:0031641 | regulation of myelination | fbxw7 | IGI | ZFIN:ZDB-GENO-160715-2 | Zfish | PMID:26538655 |
Biological Process | GO:0031641 | regulation of myelination | fbxw7 | IMP | ZFIN:ZDB-MRPHLNO-120814-3 | Zfish | PMID:28855284 |
Biological Process | GO:0032006 | regulation of TOR signaling | fbxw7 | IGI | ZFIN:ZDB-GENO-160715-2 | Zfish | PMID:26538655 |
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | FBXW7 | IDA | Human | PMID:15103331 | |
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | FBXW7 | IDA | Human | PMID:17434132 | |
Biological Process | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | Fbxw7 | IDA | Mouse | MGI:MGI:6107392|PMID:21953459 | |
Biological Process | GO:0007062 | sister chromatid cohesion | FBXW7 | IMP | Human | PMID:15917200 | |
Biological Process | GO:0001570 | vasculogenesis | Fbxw7 | IMP | Mouse | PMID:21503901 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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