Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCER2
  • Mouse genes Fcer2a
  • Rat genes Fcer2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcer2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019863	IgE binding	FCER2	IDA		Human	PMID:16172256
Molecular Function	GO:0019769	low-affinity IgE receptor activity	FCER2	IDA		Human	PMID:7544003
Molecular Function	GO:0046872	metal ion binding	FCER2	EXP		Human	PMID:16765898
Molecular Function	GO:0046872	metal ion binding	FCER2	EXP		Human	PMID:28361904
Molecular Function	GO:0005515	protein binding	FCER2	IPI	UniProtKB:P01854	Human	PMID:16172256
Molecular Function	GO:0005515	protein binding	FCER2	IPI	UniProtKB:P20023	Human	PMID:16172256
Molecular Function	GO:0005515	protein binding	FCER2	IPI	UniProtKB:P17544	Human	PMID:25416956
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:8418208
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:19414760
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:11435465
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:12882831
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:8041705
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:8566034
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:14662849
Cellular Component	GO:0009897	external side of plasma membrane	Fcer2a	IDA		Mouse	PMID:15909309
Cellular Component	GO:0070062	extracellular exosome	FCER2	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	FCER2	IDA		Human	PMID:7544003
Biological Process	GO:0002450	B cell antigen processing and presentation	FCER2	IDA		Human	PMID:2167225
Biological Process	GO:0160006	Fc receptor-mediated immune complex endocytosis	FCER2	IDA		Human	PMID:2167225
Biological Process	GO:0042116	macrophage activation	FCER2	IDA		Human	PMID:7544003
Biological Process	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	Fcer2a	IMP	MGI:MGI:3583003	Mouse	PMID:8041705
Biological Process	GO:0051712	positive regulation of killing of cells of another organism	FCER2	IDA		Human	PMID:7544003
Biological Process	GO:0051000	positive regulation of nitric-oxide synthase activity	FCER2	IDA		Human	PMID:7544003
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	FCER2	IDA		Human	PMID:7544003
Biological Process	GO:0051238	sequestering of metal ion	FCER2	EXP		Human	PMID:28361904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern