Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCGR1A,FCGR1BP
  • Mouse genes Fcgr1
  • Rat genes Fcgr1a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcgr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019771	high-affinity IgG receptor activity	FCGR1A	IDA		Human	PMID:11711607
Molecular Function	GO:0019864	IgG binding	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Molecular Function	GO:0019864	IgG binding	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Molecular Function	GO:0019864	IgG binding	Fcgr1	IDA		Mouse	PMID:9551950
Molecular Function	GO:0019770	IgG receptor activity	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Molecular Function	GO:0019770	IgG receptor activity	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Molecular Function	GO:0019770	IgG receptor activity	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:9551950
Molecular Function	GO:0031774	leukotriene receptor binding	Fcgr1a	IPI	RGD:620410	Rat	PMID:19657115|RGD:9685698
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:P21333	Human	PMID:18322202
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:O43491	Human	PMID:22003208
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:P01857	Human	PMID:25925696
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:P30273	Human	PMID:29143175
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:O00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:O43736	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:O95393	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:P07306	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q13021	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q13323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q6UX27-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q86VB7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q8IZ57	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q92520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q92982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q9BXN2-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q9H2S6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCGR1A	IPI	UniProtKB:Q9UEU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fcgr1a	IPI	RGD:629471	Rat	PMID:19657115|RGD:9685698
Cellular Component	GO:0009897	external side of plasma membrane	Fcgr1	IDA		Mouse	PMID:11911823
Cellular Component	GO:0045121	membrane raft	Fcgr1a	IDA		Rat	PMID:19657115|RGD:9685698
Cellular Component	GO:0005886	plasma membrane	FCGR1A	IDA		Human	PMID:18322202
Biological Process	GO:0001788	antibody-dependent cellular cytotoxicity	FCGR1A	IDA		Human	PMID:11711607
Biological Process	GO:0001788	antibody-dependent cellular cytotoxicity	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0001788	antibody-dependent cellular cytotoxicity	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0019884	antigen processing and presentation of exogenous antigen	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0007166	cell surface receptor signaling pathway	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0007166	cell surface receptor signaling pathway	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0007166	cell surface receptor signaling pathway	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:9551950
Biological Process	GO:0042742	defense response to bacterium	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0006911	phagocytosis, engulfment	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0006911	phagocytosis, engulfment	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0006911	phagocytosis, engulfment	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:9551950
Biological Process	GO:0006910	phagocytosis, recognition	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0006910	phagocytosis, recognition	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0006910	phagocytosis, recognition	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:9551950
Biological Process	GO:0050766	positive regulation of phagocytosis	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:9551950
Biological Process	GO:0050766	positive regulation of phagocytosis	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0050766	positive regulation of phagocytosis	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0060100	positive regulation of phagocytosis, engulfment	Fcgr1a	IMP		Rat	PMID:19657115|RGD:9685698
Biological Process	GO:0061098	positive regulation of protein tyrosine kinase activity	FCGR1A	IMP		Human	PMID:10556798
Biological Process	GO:1904058	positive regulation of sensory perception of pain	Fcgr1a	IMP		Rat	PMID:32510872|RGD:127338469
Biological Process	GO:0001798	positive regulation of type IIa hypersensitivity	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0001805	positive regulation of type III hypersensitivity	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0006898	receptor-mediated endocytosis	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0050776	regulation of immune response	Fcgr1	IMP	MGI:MGI:2679238	Mouse	PMID:11911823
Biological Process	GO:0050776	regulation of immune response	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:11911824
Biological Process	GO:0009617	response to bacterium	Fcgr1	IMP	MGI:MGI:2664927	Mouse	PMID:16836651
Biological Process	GO:0071871	response to epinephrine	Fcgr1a	IEP		Rat	PMID:18756515|RGD:9685707
Biological Process	GO:0032355	response to estradiol	Fcgr1a	IEP		Rat	PMID:24551115|RGD:9685700

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern