Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCHO2
  • Mouse genes Fcho2
  • Rat genes Fcho2
  • Zfish genes fcho2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcho2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Fcho2	IPI	UniProtKB:Q3UQN2	Mouse	MGI:MGI:5320266|PMID:21762413
Molecular Function	GO:0042802	identical protein binding	Fcho2	IPI	UniProtKB:Q3UQN2	Mouse	MGI:MGI:5926142|PMID:17540576
Molecular Function	GO:0035091	phosphatidylinositol binding	Fcho2	IDA		Mouse	MGI:MGI:5320266|PMID:21762413
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	Fcho2	IDA		Mouse	MGI:MGI:5320276|PMID:20448150
Molecular Function	GO:0001786	phosphatidylserine binding	Fcho2	IDA		Mouse	MGI:MGI:5320266|PMID:21762413
Molecular Function	GO:0005515	protein binding	FCHO2	IPI	UniProtKB:P42566	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	FCHO2	IPI	UniProtKB:P42566	Human	PMID:21762413
Molecular Function	GO:0005515	protein binding	FCHO2	IPI	UniProtKB:P98078	Human	PMID:22323290
Molecular Function	GO:0005515	protein binding	Fcho2	IPI	UniProtKB:A7BFV9	Mouse	MGI:MGI:5320276|PMID:20448150
Molecular Function	GO:0005515	protein binding	Fcho2	IPI	UniProtKB:A7BFV9	Mouse	MGI:MGI:5320266|PMID:21762413
Molecular Function	GO:0005515	protein binding	Fcho2	IPI	UniProtKB:P42566|UniProtKB:Q15811	Mouse	MGI:MGI:5320276|PMID:20448150
Cellular Component	GO:0005905	clathrin-coated pit	FCHO2	IDA		Human	PMID:21762413
Cellular Component	GO:0005905	clathrin-coated pit	FCHO2	IDA		Human	PMID:22484487
Cellular Component	GO:0005905	clathrin-coated pit	Fcho2	IDA		Mouse	MGI:MGI:5320276|PMID:20448150
Cellular Component	GO:0005905	clathrin-coated pit	Fcho2	IDA		Mouse	MGI:MGI:5320266|PMID:21762413
Cellular Component	GO:0030136	clathrin-coated vesicle	FCHO2	IDA		Human	PMID:21762413
Cellular Component	GO:0030136	clathrin-coated vesicle	Fcho2	IDA		Mouse	MGI:MGI:5320266|PMID:21762413
Cellular Component	GO:0005886	plasma membrane	Fcho2	IDA		Mouse	MGI:MGI:5320276|PMID:20448150
Cellular Component	GO:0098835	presynaptic endocytic zone membrane	Fcho2	IDA		Rat	PMID:20448150|RGD:12050101
Biological Process	GO:0043009	chordate embryonic development	fcho2	IMP	ZFIN:ZDB-MRPHLNO-120608-1	Zfish	PMID:22484487
Biological Process	GO:0048268	clathrin coat assembly	FCHO2	IMP		Human	PMID:20448150
Biological Process	GO:0072583	clathrin-dependent endocytosis	FCHO2	IMP		Human	PMID:20448150
Biological Process	GO:0072583	clathrin-dependent endocytosis	FCHO2	IMP		Human	PMID:21762413
Biological Process	GO:0010324	membrane invagination	Fcho2	IDA		Mouse	MGI:MGI:5320276|PMID:20448150
Biological Process	GO:0072659	protein localization to plasma membrane	Fcho2	IMP		Mouse	MGI:MGI:5320276|PMID:20448150
Biological Process	GO:0048488	synaptic vesicle endocytosis	Fcho2	IGI	UniProtKB:D3ZIM5|UniProtKB:D3ZYR1	Mouse	MGI:MGI:5320276|PMID:20448150
Biological Process	GO:0048488	synaptic vesicle endocytosis	Fcho2	IGI	UniProtKB:D3ZIM5|UniProtKB:Q3UQN2	Rat	PMID:20448150|RGD:12050101

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern