Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCHSD2
  • Mouse genes Fchsd2
  • Rat genes Fchsd2
  • Zfish genes si:ch211-176g13.8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fchsd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	FCHSD2	IDA		Human	PMID:29887380
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	FCHSD2	IDA		Human	PMID:29887380
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q62915	Human	PMID:14627983
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q96QZ7	Human	PMID:14627983
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:P55072	Human	PMID:18654987
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q5JR59	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q5JR59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q9NUQ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q15811	Human	PMID:29887380
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q91YD9	Human	PMID:29887380
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q8IZU0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FCHSD2	IPI	UniProtKB:Q9NUQ8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Fchsd2	IPI	UniProtKB:P70315|UniProtKB:Q91YD9	Mouse	MGI:MGI:6233193|PMID:23437151
Cellular Component	GO:0005905	clathrin-coated pit	FCHSD2	IDA		Human	PMID:29887380
Cellular Component	GO:0005886	plasma membrane	FCHSD2	IDA		Human	PMID:29887380
Cellular Component	GO:0120043	stereocilium shaft	Fchsd2	IDA		Mouse	MGI:MGI:6233193|PMID:23437151
Biological Process	GO:0072583	clathrin-dependent endocytosis	FCHSD2	IMP		Human	PMID:29887380
Biological Process	GO:0061024	membrane organization	Fchsd2	IMP		Mouse	MGI:MGI:6274959|PMID:23761074
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Fchsd2	IDA		Mouse	MGI:MGI:6233193|PMID:23437151
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	FCHSD2	IMP		Human	PMID:29887380

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern