Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCN1,FCN2
  • Mouse genes Fcnb
  • Rat genes Fcnb
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcnb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003823	antigen binding	FCN2	IDA		Human	PMID:8576206
Molecular Function	GO:0048306	calcium-dependent protein binding	FCN2	IPI	UniProtKB:O00187	Human	PMID:12421953
Molecular Function	GO:0048306	calcium-dependent protein binding	FCN2	IPI	UniProtKB:P48740	Human	PMID:12421953
Molecular Function	GO:0097367	carbohydrate derivative binding	Fcnb	IDA		Mouse	PMID:16328467
Molecular Function	GO:0001664	G protein-coupled receptor binding	FCN1	IPI	UniProtKB:O15552	Human	PMID:21037097
Molecular Function	GO:2001065	mannan binding	FCN2	IDA		Human	PMID:8576206
Molecular Function	GO:0038187	pattern recognition receptor activity	FCN1	IMP		Human	PMID:21037097
Molecular Function	GO:0005515	protein binding	FCN1	IPI	UniProtKB:Q2TS39	Human	PMID:17581635
Molecular Function	GO:0005515	protein binding	FCN1	IPI	UniProtKB:P26022	Human	PMID:19632990
Molecular Function	GO:0005515	protein binding	FCN1	IPI	UniProtKB:P02741	Human	PMID:21037097
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P26022	Human	PMID:19632990
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P48740-2	Human	PMID:19939495
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:Q07954	Human	PMID:21054788
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P26022	Human	PMID:21490156
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P17927	Human	PMID:23460739
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:O75636	Human	PMID:23785123
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P9WQP1	Human	PMID:27141819
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:P9WQP3:PRO_0000000214	Human	PMID:27141819
Molecular Function	GO:0005515	protein binding	FCN2	IPI	UniProtKB:O75636	Human	PMID:32094208
Molecular Function	GO:0043394	proteoglycan binding	FCN2	IDA		Human	PMID:8576206
Molecular Function	GO:0033691	sialic acid binding	FCN1	IDA		Human	PMID:20400674
Molecular Function	GO:0033691	sialic acid binding	Fcnb	IDA		Mouse	PMID:16328467
Cellular Component	GO:0072562	blood microparticle	FCN2	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FCN1	HDA		Human	PMID:28344315
Cellular Component	GO:0070062	extracellular exosome	FCN2	HDA		Human	PMID:19056867
Cellular Component	GO:0031232	extrinsic component of external side of plasma membrane	FCN1	IDA		Human	PMID:21037097
Cellular Component	GO:1905370	serine-type endopeptidase complex	FCN1	IDA		Human	PMID:16116205
Cellular Component	GO:1905370	serine-type endopeptidase complex	FCN2	IDA		Human	PMID:10679061
Biological Process	GO:0002752	cell surface pattern recognition receptor signaling pathway	FCN1	IMP		Human	PMID:21037097
Biological Process	GO:0001867	complement activation, lectin pathway	FCN1	IDA		Human	PMID:16116205
Biological Process	GO:0001867	complement activation, lectin pathway	FCN2	IDA		Human	PMID:10679061
Biological Process	GO:0001867	complement activation, lectin pathway	FCN2	IDA		Human	PMID:14707097
Biological Process	GO:0001867	complement activation, lectin pathway	FCN2	IDA		Human	PMID:15804047
Biological Process	GO:0050829	defense response to Gram-negative bacterium	FCN2	IDA		Human	PMID:8576206
Biological Process	GO:0050830	defense response to Gram-positive bacterium	FCN2	IDA		Human	PMID:14707097
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	FCN1	IDA		Human	PMID:21037097
Biological Process	GO:0046597	negative regulation of viral entry into host cell	FCN1	IDA		Human	PMID:22851708
Biological Process	GO:0008228	opsonization	FCN2	IDA		Human	PMID:8576206
Biological Process	GO:0032757	positive regulation of interleukin-8 production	FCN1	IMP		Human	PMID:21037097
Biological Process	GO:1903028	positive regulation of opsonization	FCN1	IDA		Human	PMID:16116205
Biological Process	GO:1903028	positive regulation of opsonization	FCN2	IDA		Human	PMID:10679061
Biological Process	GO:0034394	protein localization to cell surface	FCN1	IDA		Human	PMID:20400674
Biological Process	GO:0006508	proteolysis	FCN1	IDA		Human	PMID:16116205
Biological Process	GO:0006508	proteolysis	FCN2	IDA		Human	PMID:10679061
Biological Process	GO:0043654	recognition of apoptotic cell	FCN1	IDA		Human	PMID:15804047
Biological Process	GO:0043654	recognition of apoptotic cell	FCN2	IDA		Human	PMID:15804047

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern