Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FCRL3,FCRL5
  • Mouse genes Fcrl5
  • Rat genes Fcrl5
  • Zfish genes si:ch211-165f21.7,si:dkey-23a13.11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fcrl5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	FCRL3	IPI	UniProtKB:P43403|UniProtKB:P43405	Human	PMID:19843936
Molecular Function	GO:0019902	phosphatase binding	FCRL3	IPI	UniProtKB:P29350|UniProtKB:Q06124|UniProtKB:Q92835	Human	PMID:19843936
Molecular Function	GO:0005515	protein binding	FCRL5	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCRL5	IPI	UniProtKB:Q8TC20-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FCRL5	IPI	UniProtKB:Q9Y2J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fcrl5	IPI	PR:P29351	Mouse	PMID:23509253
Molecular Function	GO:0005515	protein binding	Fcrl5	IPI	PR:P25911	Mouse	PMID:23509253
Molecular Function	GO:0019903	protein phosphatase binding	FCRL3	IPI	UniProtKB:P29350|UniProtKB:Q06124	Human	PMID:12051764
Molecular Function	GO:1990782	protein tyrosine kinase binding	FCRL3	IPI	UniProtKB:P43403|UniProtKB:P43405	Human	PMID:12051764
Cellular Component	GO:0009986	cell surface	FCRL3	IDA		Human	PMID:16849395
Cellular Component	GO:0009986	cell surface	FCRL5	IDA		Human	PMID:16849395
Cellular Component	GO:0005886	plasma membrane	Fcrl5	IDA		Mouse	PMID:23509253
Cellular Component	GO:0043235	receptor complex	FCRL5	IDA		Human	PMID:23382219
Biological Process	GO:0050853	B cell receptor signaling pathway	Fcrl5	IGI	MGI:MGI:96055	Mouse	PMID:23509253
Biological Process	GO:0050853	B cell receptor signaling pathway	Fcrl5	IGI	MGI:MGI:96892	Mouse	PMID:23509253
Biological Process	GO:0050853	B cell receptor signaling pathway	Fcrl5	IDA		Mouse	PMID:23509253
Biological Process	GO:0051649	establishment of localization in cell	Fcrl5	IGI	MGI:MGI:96055	Mouse	PMID:23509253
Biological Process	GO:0051649	establishment of localization in cell	Fcrl5	IDA		Mouse	PMID:23509253
Biological Process	GO:0051649	establishment of localization in cell	Fcrl5	IGI	MGI:MGI:96892	Mouse	PMID:23509253
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	FCRL3	IDA		Human	PMID:19843936
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	Fcrl5	IGI	MGI:MGI:96055	Mouse	PMID:23509253
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	Fcrl5	IGI	MGI:MGI:96892	Mouse	PMID:23509253
Biological Process	GO:0050859	negative regulation of B cell receptor signaling pathway	Fcrl5	IDA		Mouse	PMID:23509253
Biological Process	GO:0002638	negative regulation of immunoglobulin production	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	Fcrl5	IDA		Mouse	PMID:23509253
Biological Process	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	Fcrl5	IGI	MGI:MGI:96055	Mouse	PMID:23509253
Biological Process	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	Fcrl5	IGI	MGI:MGI:96892	Mouse	PMID:23509253
Biological Process	GO:0030890	positive regulation of B cell proliferation	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:0043410	positive regulation of MAPK cascade	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:1905184	positive regulation of protein serine/threonine phosphatase activity	FCRL3	IDA		Human	PMID:12051764
Biological Process	GO:0050864	regulation of B cell activation	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:0045577	regulation of B cell differentiation	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:0090279	regulation of calcium ion import	FCRL3	IDA		Human	PMID:19843936
Biological Process	GO:0034163	regulation of toll-like receptor 9 signaling pathway	FCRL3	IDA		Human	PMID:23857366
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Fcrl5	IGI	MGI:MGI:96055	Mouse	PMID:23509253
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Fcrl5	IDA		Mouse	PMID:23509253
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Fcrl5	IGI	MGI:MGI:96892	Mouse	PMID:23509253

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern