Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fer

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FER
- Mouse genes Fer
- Rat genes Fer
- Zfish genes fer
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fer

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005154	epidermal growth factor receptor binding	FER	IDA		Human	PMID:21518868
Molecular Function	GO:0008289	lipid binding	FER	IDA		Human	PMID:19738202
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	FER	IDA		Human	PMID:12972546
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	FER	IDA		Human	PMID:19738202
Molecular Function	GO:0005515	protein binding	FER	IPI	UniProtKB:O42486	Human	PMID:15226396
Molecular Function	GO:0005515	protein binding	FER	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	FER	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	FER	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	FER	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Fer	IPI	UniProtKB:Q9QXS1	Mouse	PMID:12200133
Molecular Function	GO:0005515	protein binding	Fer	IPI	PR:P42227	Mouse	PMID:12738762
Molecular Function	GO:0005515	protein binding	Fer	IPI	PR:P52332	Mouse	PMID:12738762
Molecular Function	GO:0004672	protein kinase activity	Fer	IDA		Mouse	PMID:12192036
Molecular Function	GO:0008157	protein phosphatase 1 binding	Fer	IPI	UniProtKB:P62136	Mouse	MGI:MGI:5319613\|PMID:16732323
Cellular Component	GO:0015629	actin cytoskeleton	FER	IDA		Human	PMID:19738202
Cellular Component	GO:0005912	adherens junction	Fer	IDA		Rat	PMID:12700184\|RGD:2291909
Cellular Component	GO:0030054	cell junction	FER	IDA		Human	PMID:12972546
Cellular Component	GO:0000785	chromatin	FER	IDA		Human	PMID:1990274
Cellular Component	GO:0005737	cytoplasm	FER	IDA		Human	PMID:1990274
Cellular Component	GO:0005829	cytosol	FER	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	FER	IDA		Human	PMID:19738202
Cellular Component	GO:0030027	lamellipodium	FER	IDA		Human	PMID:19738202
Cellular Component	GO:0015630	microtubule cytoskeleton	FER	IDA		Human	PMID:12972546
Cellular Component	GO:0005634	nucleus	FER	IDA		Human	PMID:19147545
Cellular Component	GO:0032991	protein-containing complex	Fer	IDA		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0031532	actin cytoskeleton reorganization	Fer	IMP		Mouse	MGI:MGI:3620305\|PMID:16176974
Biological Process	GO:0034333	adherens junction assembly	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0120179	adherens junction disassembly	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0001568	blood vessel development	fer	IMP	ZFIN:ZDB-MRPHLNO-180427-1	Zfish	PMID:29168762
Biological Process	GO:0007155	cell adhesion	Fer	IMP	MGI:MGI:2180299	Mouse	PMID:12192036
Biological Process	GO:0044331	cell-cell adhesion mediated by cadherin	Fer	IMP		Mouse	MGI:MGI:3620305\|PMID:16176974
Biological Process	GO:0032869	cellular response to insulin stimulus	Fer	IDA		Mouse	MGI:MGI:1928184\|PMID:11006284
Biological Process	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	FER	IMP		Human	PMID:9722593
Biological Process	GO:0034614	cellular response to reactive oxygen species	Fer	IMP		Mouse	MGI:MGI:3723409\|PMID:17606629
Biological Process	GO:0006935	chemotaxis	Fer	IMP	MGI:MGI:2180299	Mouse	PMID:12192036
Biological Process	GO:0060027	convergent extension involved in gastrulation	fer	IMP	ZFIN:ZDB-MRPHLNO-141208-2	Zfish	PMID:25184253
Biological Process	GO:0019221	cytokine-mediated signaling pathway	FER	IMP		Human	PMID:9722593
Biological Process	GO:0050904	diapedesis	Fer	IMP		Mouse	MGI:MGI:5319615\|PMID:16009680
Biological Process	GO:0048821	erythrocyte development	fer	IMP	ZFIN:ZDB-MRPHLNO-180427-1	Zfish	PMID:29168762
Biological Process	GO:0035426	extracellular matrix-cell signaling	Fer	IMP		Mouse	MGI:MGI:3723409\|PMID:17606629
Biological Process	GO:0038095	Fc-epsilon receptor signaling pathway	Fer	IMP		Mouse	MGI:MGI:2385502\|PMID:12192036
Biological Process	GO:0007281	germ cell development	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	Fer	IDA		Mouse	MGI:MGI:1928184\|PMID:11006284
Biological Process	GO:0070102	interleukin-6-mediated signaling pathway	FER	IMP		Human	PMID:19147545
Biological Process	GO:0038109	Kit signaling pathway	Fer	IMP		Mouse	MGI:MGI:2385502\|PMID:12192036
Biological Process	GO:0008584	male gonad development	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0000226	microtubule cytoskeleton organization	FER	IMP		Human	PMID:12972546
Biological Process	GO:0033007	negative regulation of mast cell activation involved in immune response	Fer	IMP		Mouse	MGI:MGI:3694314\|PMID:16731527
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	FER	IDA		Human	PMID:12972546
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	FER	IDA		Human	PMID:19738202
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Fer	IDA		Mouse	MGI:MGI:5319623\|PMID:7623846
Biological Process	GO:0030838	positive regulation of actin filament polymerization	FER	IMP		Human	PMID:19738202
Biological Process	GO:0030335	positive regulation of cell migration	FER	IMP		Human	PMID:19738202
Biological Process	GO:0008284	positive regulation of cell population proliferation	FER	IMP		Human	PMID:25540073
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	FER	IMP		Human	PMID:21518868
Biological Process	GO:0046777	protein autophosphorylation	FER	IDA		Human	PMID:7623846
Biological Process	GO:0046777	protein autophosphorylation	Fer	IDA		Mouse	PMID:12192036
Biological Process	GO:0006468	protein phosphorylation	Fer	IDA		Mouse	PMID:12192036
Biological Process	GO:0042058	regulation of epidermal growth factor receptor signaling pathway	FER	IMP		Human	PMID:21518868
Biological Process	GO:0010762	regulation of fibroblast migration	Fer	IMP		Mouse	MGI:MGI:3723409\|PMID:17606629
Biological Process	GO:0010591	regulation of lamellipodium assembly	FER	IDA		Human	PMID:19738202
Biological Process	GO:0001932	regulation of protein phosphorylation	Fer	IMP		Mouse	MGI:MGI:5319613\|PMID:16732323
Biological Process	GO:0032496	response to lipopolysaccharide	Fer	IMP		Mouse	MGI:MGI:5319615\|PMID:16009680
Biological Process	GO:0036119	response to platelet-derived growth factor	Fer	IDA		Mouse	MGI:MGI:5319623\|PMID:7623846
Biological Process	GO:0072520	seminiferous tubule development	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0060009	Sertoli cell development	Fer	IEP		Rat	PMID:12700184\|RGD:2291909
Biological Process	GO:0007165	signal transduction	Fer	IDA		Mouse	PMID:12192036
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Fer	IMP		Mouse	MGI:MGI:3620305\|PMID:16176974
Biological Process	GO:0007260	tyrosine phosphorylation of STAT protein	FER	IDA		Human	PMID:19147545

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.