Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FERMT1
  • Mouse genes Fermt1
  • Rat genes Fermt1
  • Zfish genes fermt1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fermt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Fermt1	IDA		Mouse	PMID:16876785
Cellular Component	GO:0030054	cell junction	FERMT1	IDA		Human	PMID:17012746
Cellular Component	GO:0071944	cell periphery	FERMT1	IDA		Human	PMID:18528435
Cellular Component	GO:0005737	cytoplasm	FERMT1	IDA		Human	PMID:18528435
Cellular Component	GO:0005829	cytosol	FERMT1	IDA		Human	PMID:17012746
Cellular Component	GO:0005925	focal adhesion	FERMT1	IDA		Human	PMID:18528435
Cellular Component	GO:0005925	focal adhesion	Fermt1	IDA		Mouse	PMID:16876785
Biological Process	GO:0071711	basement membrane organization	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0007155	cell adhesion	FERMT1	IDA		Human	PMID:17012746
Biological Process	GO:0007155	cell adhesion	FERMT1	IGI	UniProtKB:Q96AC1	Human	PMID:21356350
Biological Process	GO:0090162	establishment of epithelial cell polarity	FERMT1	IDA		Human	PMID:17012746
Biological Process	GO:0051546	keratinocyte migration	FERMT1	IDA		Human	PMID:17012746
Biological Process	GO:0043616	keratinocyte proliferation	FERMT1	IDA		Human	PMID:17012746
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0010629	negative regulation of gene expression	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0042308	negative regulation of protein import into nucleus	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0051886	negative regulation of timing of anagen	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0033625	positive regulation of integrin activation	FERMT1	IGI	UniProtKB:Q96AC1	Human	PMID:21356350
Biological Process	GO:0071636	positive regulation of transforming growth factor beta production	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	Fermt1	IMP		Mouse	MGI:MGI:5571208|PMID:24681597
Biological Process	GO:1903691	positive regulation of wound healing, spreading of epidermal cells	FERMT1	IGI	UniProtKB:Q96AC1	Human	PMID:21356350

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern