Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FES
  • Mouse genes Fes
  • Rat genes Fes
  • Zfish genes fes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fes

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034987	immunoglobulin receptor binding	FES	IDA		Human	PMID:19001085
Molecular Function	GO:0008017	microtubule binding	Fes	IDA		Mouse	PMID:14551201
Molecular Function	GO:0004715	non-membrane spanning protein tyrosine kinase activity	FES	IDA		Human	PMID:15485904
Molecular Function	GO:0035091	phosphatidylinositol binding	FES	IDA		Human	PMID:19001085
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P15311	Human	PMID:18046454
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P15924	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	FES	IPI	UniProtKB:P15924	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Fes	IPI	UniProtKB:P01901|UniProtKB:P35235	Mouse	MGI:MGI:5432331|PMID:22522491
Molecular Function	GO:0004672	protein kinase activity	Fes	IDA		Mouse	PMID:12192036
Molecular Function	GO:0004713	protein tyrosine kinase activity	FES	IDA		Human	PMID:11509660
Cellular Component	GO:0005737	cytoplasm	FES	IDA		Human	PMID:11339827
Cellular Component	GO:0031410	cytoplasmic vesicle	FES	IDA		Human	PMID:11339827
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	FES	IDA		Human	PMID:18046454
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	FES	IDA		Human	PMID:19001085
Cellular Component	GO:0005925	focal adhesion	FES	IDA		Human	PMID:18046454
Cellular Component	GO:0015630	microtubule cytoskeleton	FES	IDA		Human	PMID:15485904
Cellular Component	GO:0015630	microtubule cytoskeleton	Fes	IDA		Mouse	PMID:14551201
Biological Process	GO:0060038	cardiac muscle cell proliferation	Fes	IEP		Rat	PMID:2447874|RGD:151665807
Biological Process	GO:0071305	cellular response to vitamin D	FES	IMP		Human	PMID:28389358
Biological Process	GO:0007098	centrosome cycle	Fes	IMP		Mouse	PMID:14551201
Biological Process	GO:0001578	microtubule bundle formation	Fes	IDA		Mouse	PMID:14551201
Biological Process	GO:0051450	myoblast proliferation	Fes	IEP		Rat	PMID:2425941|RGD:151667421
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	FES	IDA		Human	PMID:11509660
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	FES	IDA		Human	PMID:15485904
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	FES	IMP		Human	PMID:15302586
Biological Process	GO:0031116	positive regulation of microtubule polymerization	FES	IMP		Human	PMID:15485904
Biological Process	GO:0045657	positive regulation of monocyte differentiation	FES	IMP		Human	PMID:28389358
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	FES	IMP		Human	PMID:2656706
Biological Process	GO:0010976	positive regulation of neuron projection development	FES	IMP		Human	PMID:15302586
Biological Process	GO:0046777	protein autophosphorylation	FES	IDA		Human	PMID:7687763
Biological Process	GO:0030155	regulation of cell adhesion	FES	IMP		Human	PMID:11509660
Biological Process	GO:0045595	regulation of cell differentiation	FES	IMP		Human	PMID:15302586
Biological Process	GO:2000145	regulation of cell motility	FES	IMP		Human	PMID:18046454
Biological Process	GO:0042127	regulation of cell population proliferation	FES	IMP		Human	PMID:11509660
Biological Process	GO:0008360	regulation of cell shape	FES	IMP		Human	PMID:11509660
Biological Process	GO:0008360	regulation of cell shape	FES	IMP		Human	PMID:18046454
Biological Process	GO:0043304	regulation of mast cell degranulation	FES	IMP		Human	PMID:19001085

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern