Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FEZ1
  • Mouse genes Fez1
  • Rat genes Fez1
  • Zfish genes fez1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fez1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043015	gamma-tubulin binding	Fez1	IDA		Mouse	PMID:15649943
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:Q96PY6	Human	PMID:14690447
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:P42858	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:Q9P2H0	Human	PMID:15383276
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:O14530	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:P17210	Human	PMID:20547877
Molecular Function	GO:0005515	protein binding	FEZ1	IPI	UniProtKB:P42858	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Fez1	IPI	PR:P25233	Mouse	PMID:15649943
Molecular Function	GO:0005515	protein binding	Fez1	IPI	PR:Q9QZ04	Mouse	PMID:15649943
Molecular Function	GO:0005515	protein binding	Fez1	IPI	RGD:621559	Rat	PMID:17669366|RGD:2316312
Molecular Function	GO:0005515	protein binding	Fez1	IPI	RGD:3399	Rat	PMID:9971736|RGD:728650
Molecular Function	GO:0005080	protein kinase C binding	Fez1	IPI	RGD:3399	Rat	PMID:9971736|RGD:728650
Cellular Component	GO:0030424	axon	Fez1	IDA		Rat	PMID:17173861|RGD:13208824
Cellular Component	GO:0030424	axon	Fez1	IDA		Rat	PMID:19199094|RGD:2316311
Cellular Component	GO:0042995	cell projection	Fez1	IDA		Rat	PMID:19199094|RGD:2316311
Cellular Component	GO:0005813	centrosome	Fez1	IDA		Mouse	PMID:15649943
Cellular Component	GO:0005737	cytoplasm	Fez1	IDA		Mouse	PMID:15649943
Cellular Component	GO:0005737	cytoplasm	Fez1	IDA		Rat	PMID:19199094|RGD:2316311
Cellular Component	GO:0030425	dendrite	Fez1	IDA		Rat	PMID:17173861|RGD:13208824
Cellular Component	GO:0030425	dendrite	Fez1	IDA		Rat	PMID:19199094|RGD:2316311
Cellular Component	GO:0005794	Golgi apparatus	FEZ1	IDA		Human	PMID:25495476
Cellular Component	GO:0030426	growth cone	Fez1	IDA		Rat	PMID:12874605|RGD:13208828
Cellular Component	GO:0005739	mitochondrion	Fez1	IDA		Rat	PMID:17669366|RGD:2316312
Cellular Component	GO:0043025	neuronal cell body	Fez1	IDA		Rat	PMID:17173861|RGD:13208824
Cellular Component	GO:0005886	plasma membrane	Fez1	IDA		Rat	PMID:9971736|RGD:728650
Biological Process	GO:0071363	cellular response to growth factor stimulus	Fez1	IEP		Rat	PMID:17669366|RGD:2316312
Biological Process	GO:0030010	establishment of cell polarity	Fez1	IMP		Rat	PMID:17173861|RGD:13208824
Biological Process	GO:0051654	establishment of mitochondrion localization	Fez1	IMP		Rat	PMID:17669366|RGD:2316312
Biological Process	GO:0021766	hippocampus development	Fez1	IEP		Rat	PMID:14992819|RGD:13208825
Biological Process	GO:0070584	mitochondrion morphogenesis	Fez1	IMP		Rat	PMID:17173861|RGD:13208824
Biological Process	GO:1902902	negative regulation of autophagosome assembly	FEZ1	IMP		Human	PMID:25495476
Biological Process	GO:0061881	positive regulation of anterograde axonal transport of mitochondrion	Fez1	IMP		Rat	PMID:17173861|RGD:13208824
Biological Process	GO:0010976	positive regulation of neuron projection development	Fez1	IMP		Rat	PMID:17669366|RGD:2316312

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern