Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGD2
  • Mouse genes Fgd2
  • Rat genes Fgd2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Fgd2	IDA		Mouse	PMID:18838382
Molecular Function	GO:1901981	phosphatidylinositol phosphate binding	Fgd2	IDA		Mouse	PMID:18838382
Molecular Function	GO:0005515	protein binding	FGD2	IPI	UniProtKB:Q53G59	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGD2	IPI	UniProtKB:Q8WW34	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FGD2	IPI	UniProtKB:Q58EX7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FGD2	IPI	UniProtKB:Q9NS64	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Fgd2	IDA		Mouse	PMID:18838382
Cellular Component	GO:0005769	early endosome	Fgd2	IDA		Mouse	PMID:18838382
Cellular Component	GO:0005634	nucleus	Fgd2	IDA		Mouse	PMID:18838382
Cellular Component	GO:0001726	ruffle	Fgd2	IDA		Mouse	PMID:18838382
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Fgd2	IGI	MGI:MGI:106211	Mouse	PMID:18838382

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern