Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGD4
  • Mouse genes Fgd4
  • Rat genes Fgd4
  • Zfish genes fgd4a,fgd4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgd4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Fgd4	IDA		Rat	PMID:9668039|RGD:1299389
Molecular Function	GO:0051015	actin filament binding	Fgd4	IMP		Rat	PMID:9668039|RGD:1299389
Cellular Component	GO:0030175	filopodium	Fgd4	IDA		Mouse	PMID:11527409
Cellular Component	GO:0030027	lamellipodium	Fgd4	IDA		Mouse	PMID:11527409
Biological Process	GO:0030032	lamellipodium assembly	Fgd4	IDA		Mouse	PMID:11527409
Biological Process	GO:0030035	microspike assembly	Fgd4	IDA		Mouse	PMID:11527409
Biological Process	GO:0046330	positive regulation of JNK cascade	Fgd4	IMP		Rat	PMID:9668039|RGD:1299389
Biological Process	GO:0043507	positive regulation of JUN kinase activity	Fgd4	IDA		Rat	PMID:9668039|RGD:1299389
Biological Process	GO:0008360	regulation of cell shape	Fgd4	IMP		Rat	PMID:9668039|RGD:1299389

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern