Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGF22
  • Mouse genes Fgf22
  • Rat genes Fgf22
  • Zfish genes fgf22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgf22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Fgf22	IPI	PR:O70514	Mouse	PMID:15806171
Cellular Component	GO:0009986	cell surface	Fgf22	IDA		Mouse	PMID:12837279
Cellular Component	GO:0005794	Golgi apparatus	Fgf22	IDA		Mouse	PMID:12837279
Cellular Component	GO:0005730	nucleolus	Fgf22	IDA		Mouse	PMID:12837279
Biological Process	GO:0033278	cell proliferation in midbrain	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-1	Zfish	PMID:23789101
Biological Process	GO:0033278	cell proliferation in midbrain	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-2	Zfish	PMID:23789101
Biological Process	GO:0030901	midbrain development	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-1	Zfish	PMID:23789101
Biological Process	GO:0030901	midbrain development	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-2	Zfish	PMID:23789101
Biological Process	GO:0030917	midbrain-hindbrain boundary development	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-2	Zfish	PMID:23789101
Biological Process	GO:0030917	midbrain-hindbrain boundary development	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-1	Zfish	PMID:23789101
Biological Process	GO:0021509	roof plate formation	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-2	Zfish	PMID:23789101
Biological Process	GO:0021509	roof plate formation	fgf22	IMP	ZFIN:ZDB-MRPHLNO-130911-1	Zfish	PMID:23789101

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern