Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGG
  • Mouse genes Fgg
  • Rat genes Fgg
  • Zfish genes fgg
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	FGG	IPI	UniProtKB:P05362	Human	PMID:7822297
Molecular Function	GO:0005201	extracellular matrix structural constituent	FGG	HDA		Human	PMID:28344315
Molecular Function	GO:0042802	identical protein binding	Fgg	IPI	RGD:2613	Rat	PMID:21448983|RGD:11352703
Molecular Function	GO:0005515	protein binding	FGG	IPI	UniProtKB:P14738	Human	PMID:10788510
Molecular Function	GO:0005515	protein binding	FGG	IPI	UniProtKB:Q2G015	Human	PMID:10788510
Molecular Function	GO:0005515	protein binding	FGG	IPI	UniProtKB:P75358	Human	PMID:21546586
Molecular Function	GO:0005515	protein binding	FGG	IPI	UniProtKB:Q2FZB8	Human	PMID:26627825
Molecular Function	GO:0005102	signaling receptor binding	FGG	IPI	UniProtKB:P05362	Human	PMID:7822297
Molecular Function	GO:0005198	structural molecule activity	FGG	IDA		Human	PMID:8910396
Cellular Component	GO:0072562	blood microparticle	FGG	HDA		Human	PMID:22516433
Cellular Component	GO:0072562	blood microparticle	Fgg	IDA		Rat	PMID:22014850|RGD:5688769
Cellular Component	GO:0005938	cell cortex	Fgg	IDA		Mouse	PMID:15914557
Cellular Component	GO:0009986	cell surface	FGG	IDA		Human	PMID:6777381
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FGG	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FGG	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FGG	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FGG	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Fgg	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Fgg	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	Fgg	IDA		Rat	PMID:21685370|RGD:7175292
Cellular Component	GO:0009897	external side of plasma membrane	FGG	IDA		Human	PMID:6777381
Cellular Component	GO:0070062	extracellular exosome	FGG	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FGG	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	FGG	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	FGG	IDA		Human	PMID:6777381
Cellular Component	GO:0005577	fibrinogen complex	FGG	IDA		Human	PMID:16846481
Cellular Component	GO:0005577	fibrinogen complex	FGG	IDA		Human	PMID:18676163
Cellular Component	GO:0005577	fibrinogen complex	FGG	IDA		Human	PMID:6451630
Cellular Component	GO:0005577	fibrinogen complex	FGG	IDA		Human	PMID:8470043
Cellular Component	GO:0005577	fibrinogen complex	FGG	IDA		Human	PMID:8910396
Cellular Component	GO:0031091	platelet alpha granule	FGG	IDA		Human	PMID:6777381
Cellular Component	GO:0045202	synapse	Fgg	EXP		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Fgg	IDA		Mouse	PMID:16452087
Biological Process	GO:0072378	blood coagulation, fibrin clot formation	FGG	IMP		Human	PMID:11001902
Biological Process	GO:0072378	blood coagulation, fibrin clot formation	FGG	IDA		Human	PMID:16846481
Biological Process	GO:0072378	blood coagulation, fibrin clot formation	fgg	IGI	ZFIN:ZDB-MRPHLNO-140115-3,ZFIN:ZDB-MRPHLNO-140115-4,ZFIN:ZDB-MRPHLNO-140115-5	Zfish	PMID:24098662
Biological Process	GO:0007160	cell-matrix adhesion	FGG	IDA		Human	PMID:10903502
Biological Process	GO:0071347	cellular response to interleukin-1	Fgg	IEP		Rat	PMID:11071643|RGD:731198
Biological Process	GO:0071354	cellular response to interleukin-6	Fgg	IEP		Rat	PMID:11071643|RGD:731198
Biological Process	GO:0042730	fibrinolysis	FGG	IDA		Human	PMID:16846481
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	FGG	IDA		Human	PMID:10903502
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	FGG	IDA		Human	PMID:10903502
Biological Process	GO:0090331	negative regulation of platelet aggregation	Fgg	IDA		Rat	PMID:22985603|RGD:11352706
Biological Process	GO:0031639	plasminogen activation	FGG	IDA		Human	PMID:16846481
Biological Process	GO:0070527	platelet aggregation	FGG	IDA		Human	PMID:6281794
Biological Process	GO:0036345	platelet maturation	Fgg	IEP		Rat	PMID:1991167|RGD:11352701
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	FGG	IDA		Human	PMID:10903502
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	FGG	IDA		Human	PMID:19193866
Biological Process	GO:0045921	positive regulation of exocytosis	FGG	IDA		Human	PMID:19193866
Biological Process	GO:0034116	positive regulation of heterotypic cell-cell adhesion	FGG	IDA		Human	PMID:8100742
Biological Process	GO:0090277	positive regulation of peptide hormone secretion	FGG	IDA		Human	PMID:19193866
Biological Process	GO:0050714	positive regulation of protein secretion	FGG	IDA		Human	PMID:19193866
Biological Process	GO:0045907	positive regulation of vasoconstriction	FGG	IDA		Human	PMID:15739255
Biological Process	GO:0051258	protein polymerization	FGG	IMP		Human	PMID:12706644
Biological Process	GO:0009306	protein secretion	FGG	IMP		Human	PMID:18676163
Biological Process	GO:0065003	protein-containing complex assembly	FGG	IDA		Human	PMID:8910396
Biological Process	GO:0051592	response to calcium ion	FGG	IDA		Human	PMID:6777381

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern