Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGL2
  • Mouse genes Fgl2
  • Rat genes Fgl2
  • Zfish genes fgl2a,fgl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0062023	collagen-containing extracellular matrix	FGL2	HDA		Human	PMID:28327460
Cellular Component	GO:0070062	extracellular exosome	FGL2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FGL2	HDA		Human	PMID:23533145
Biological Process	GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118
Biological Process	GO:0050687	negative regulation of defense response to virus	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118
Biological Process	GO:0002605	negative regulation of dendritic cell antigen processing and presentation	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118
Biological Process	GO:0002617	negative regulation of macrophage antigen processing and presentation	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118
Biological Process	GO:0043381	negative regulation of memory T cell differentiation	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118
Biological Process	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	Fgl2	IMP	MGI:MGI:3582343	Mouse	PMID:29341118

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern