Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FHIT
  • Mouse genes Fhit
  • Rat genes Fhit
  • Zfish genes fhit
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fhit

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043530	adenosine 5'-monophosphoramidase activity	FHIT	IDA		Human	PMID:18694747
Molecular Function	GO:0047627	adenylylsulfatase activity	FHIT	IDA		Human	PMID:18694747
Molecular Function	GO:0047352	adenylylsulfate-ammonia adenylyltransferase activity	FHIT	IDA		Human	PMID:26181368
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	FHIT	IDA		Human	PMID:8794732
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	FHIT	IDA		Human	PMID:9323207
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	FHIT	IDA		Human	PMID:9543008
Molecular Function	GO:0047710	bis(5'-adenosyl)-triphosphatase activity	Fhit	IDA		Rat	PMID:16359767|RGD:2289929
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:18077326
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:24722188
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:27107012
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:32296183
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:9261067
Molecular Function	GO:0042802	identical protein binding	FHIT	IPI	UniProtKB:P49789	Human	PMID:9576908
Molecular Function	GO:0016151	nickel cation binding	Fhit	IDA		Rat	PMID:11768238|RGD:632724
Molecular Function	GO:0005515	protein binding	FHIT	IPI	UniProtKB:P35222	Human	PMID:18077326
Molecular Function	GO:0005515	protein binding	FHIT	IPI	UniProtKB:Q9UJU2	Human	PMID:18077326
Molecular Function	GO:0005515	protein binding	FHIT	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FHIT	IPI	UniProtKB:Q00987	Human	PMID:15313915
Cellular Component	GO:0005737	cytoplasm	FHIT	IDA		Human	PMID:15007172
Cellular Component	GO:0005737	cytoplasm	Fhit	IDA		Mouse	MGI:MGI:1276252|PMID:9699672
Cellular Component	GO:0005829	cytosol	FHIT	IDA		Human	PMID:15313915
Cellular Component	GO:0005829	cytosol	Fhit	IDA		Rat	PMID:16359767|RGD:2289929
Cellular Component	GO:0001650	fibrillar center	FHIT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Fhit	IDA		Rat	PMID:11768238|RGD:632724
Cellular Component	GO:0005886	plasma membrane	FHIT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Fhit	IDA		Rat	PMID:11768238|RGD:632724
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	FHIT	IDA		Human	PMID:8794732
Biological Process	GO:0015964	diadenosine triphosphate catabolic process	Fhit	IDA		Rat	PMID:16359767|RGD:2289929
Biological Process	GO:0006260	DNA replication	Fhit	IDA		Mouse	PMID:15254237
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	FHIT	IMP		Human	PMID:15313915
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	FHIT	IMP		Human	PMID:15313915
Biological Process	GO:0006163	purine nucleotide metabolic process	FHIT	IDA		Human	PMID:9323207

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern