Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FHL2
  • Mouse genes Fhl2
  • Rat genes Fhl2
  • Zfish genes fhl2a,fhl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fhl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043425	bHLH transcription factor binding	Fhl2	IPI	UniProtKB:Q64279	Mouse	MGI:MGI:3511603|PMID:15509787
Molecular Function	GO:0042802	identical protein binding	FHL2	IPI	UniProtKB:Q14192	Human	PMID:10906324
Molecular Function	GO:0042802	identical protein binding	FHL2	IPI	UniProtKB:Q14192	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P38398	Human	PMID:14550570
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q12778	Human	PMID:15692560
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q96EB6	Human	PMID:15692560
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P51610-1	Human	PMID:16624878
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NYA1	Human	PMID:16888242
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9ERP3	Human	PMID:17360532
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P18847	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q02535	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9H9D4	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q15327	Human	PMID:19608030
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P48380	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P38398	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UBI6	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q13492	Human	PMID:22829078
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O43699	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P14923	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P48380	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P52739-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q02086	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q0VD86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q16656	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q49A26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q53HC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q5T5P2-6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q5VZL5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q63ZY3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q86UW9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8IYX7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8TAU3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9BRR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9BZQ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9H2G9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NPI6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NTW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UBI6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9Y5P3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:W5RWE1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:A0A0S2Z5G4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:B4DE54	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N9N5-2	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N9N5-7	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NYN1	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q711Q0	Human	PMID:28717008
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P48380	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NTW7	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P05814	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P14923	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P48380	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q0VD86	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q49A26	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q53HC0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8IYX7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N9N5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NPI6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NTW7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UBI6	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9Y5P3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:A0PJW8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:A2BDD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:E9PSE9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O14639-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O15535	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O43189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O75155	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O75398	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O94993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O95863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P05814	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P13984	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P14923	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P17027	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P25490	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P32780	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P33176	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P48380	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P50150	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P52739-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P52747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P55347	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P80217-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:P98182	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q02086-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q02535	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q0D2K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q12772	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q13422-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q14005-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q2TAL8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q3KP44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q49A12	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q49A26-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q53HC0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q53TS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q5SW96	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q5T3J3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q658L1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q6F5E7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q6IS01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q6MZQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q7L5A3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q7Z3K3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q7Z5V6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q86UV6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q86VK4-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8IVT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8IZP0-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8ND83	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8TAG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8TDR4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8WWY6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q8WXI9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q96BD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q96KN3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9BZQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9C004	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9H1P6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9H8W3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NPI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NQ31	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NQ94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NQV5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NQX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NYA3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9NYN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UBI6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UJ55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UKD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9UMQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9Y4X4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9Y5P3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FHL2	IPI	UniProtKB:Q9C0C2	Human	PMID:33787085
Molecular Function	GO:0005515	protein binding	Fhl2	IPI	UniProtKB:Q8CIH5	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Fhl2	IPI	RGD:620048	Rat	PMID:16888242|RGD:2311372
Molecular Function	GO:0003714	transcription corepressor activity	Fhl2	IDA		Mouse	MGI:MGI:3511603|PMID:15509787
Molecular Function	GO:0008134	transcription factor binding	FHL2	IPI	UniProtKB:Q12778	Human	PMID:15692560
Cellular Component	GO:0005925	focal adhesion	FHL2	HDA		Human	PMID:21423176
Cellular Component	GO:0031430	M band	Fhl2	IDA		Rat	PMID:11062252|RGD:1582480
Cellular Component	GO:0005634	nucleus	Fhl2	IDA		Mouse	PMID:12151099
Cellular Component	GO:0005634	nucleus	Fhl2	IDA		Mouse	PMID:15509787
Cellular Component	GO:0030018	Z disc	Fhl2	IDA		Mouse	MGI:MGI:5444535|PMID:22851699
Cellular Component	GO:0030018	Z disc	Fhl2	IDA		Rat	PMID:11062252|RGD:1582480
Cellular Component	GO:0030018	Z disc	Fhl2	IDA		Rat	PMID:22851699|RGD:13601990
Biological Process	GO:0055014	atrial cardiac muscle cell development	Fhl2	IEP		Mouse	MGI:MGI:3511603|PMID:15509787
Biological Process	GO:0060347	heart trabecula formation	Fhl2	IEP		Mouse	MGI:MGI:3511603|PMID:15509787
Biological Process	GO:0043066	negative regulation of apoptotic process	FHL2	IDA		Human	PMID:15692560
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	FHL2	IMP		Human	PMID:22851699
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	Fhl2	IMP		Mouse	MGI:MGI:5444535|PMID:22851699
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	Fhl2	IMP		Rat	PMID:22851699|RGD:13601990
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FHL2	IDA		Human	PMID:15692560
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Fhl2	IDA		Mouse	MGI:MGI:3511603|PMID:15509787
Biological Process	GO:0001649	osteoblast differentiation	Fhl2	IEP		Mouse	MGI:MGI:3828402|PMID:16311053
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Fhl2	IDA		Mouse	PMID:12151099
Biological Process	GO:0009725	response to hormone	FHL2	IMP		Human	PMID:17975004
Biological Process	GO:0055015	ventricular cardiac muscle cell development	Fhl2	IEP		Mouse	MGI:MGI:3511603|PMID:15509787

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern