Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FKBP8
  • Mouse genes Fkbp8
  • Rat genes Fkbp8
  • Zfish genes fkbp8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fkbp8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	FKBP8	EXP		Human	PMID:20707607
Molecular Function	GO:0005516	calmodulin binding	FKBP8	EXP		Human	PMID:24145868
Molecular Function	GO:0005516	calmodulin binding	FKBP8	IPI	UniProtKB:P0DP23	Human	PMID:24145868
Molecular Function	GO:0097718	disordered domain specific binding	FKBP8	IPI	UniProtKB:P10415	Human	PMID:15733859
Molecular Function	GO:0042802	identical protein binding	FKBP8	IPI	UniProtKB:Q14318	Human	PMID:17024179
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O39474	Human	PMID:16844119
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O39474	Human	PMID:17024179
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P07900	Human	PMID:17024179
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q5T4F4	Human	PMID:17082457
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9GZT9	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9P035	Human	PMID:18160438
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:18216108
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q5T4F4	Human	PMID:18459960
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P00533	Human	PMID:20029029
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P07900	Human	PMID:21360678
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:24169621
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O75344	Human	PMID:26567527
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:26567527
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:C5E526	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P03431	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q1K9H5	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q5EP37	Human	PMID:28169297
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O95166,UniProtKB:P60520,UniProtKB:Q9BXW4,UniProtKB:Q9GZQ8,UniProtKB:Q9H0R8,UniProtKB:Q9H492	Human	PMID:28381481
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O95166,UniProtKB:Q9GZQ8,UniProtKB:Q9H492	Human	PMID:28381481
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O95166,UniProtKB:Q9H492	Human	PMID:28381481
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9GZQ8	Human	PMID:31908024
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O00623	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P11912	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P25025	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:P78383	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q3SXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q53TN4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q6NTF9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q86VR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q8TBM7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q8TBP5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q92915-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q96B21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q96HE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9BS91	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9BTV4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9H3N1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9NY72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FKBP8	IPI	UniProtKB:Q9Y282	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fkbp8	IPI	PR:Q8VHE6	Mouse	PMID:29916806
Molecular Function	GO:0005515	protein binding	Fkbp8	IPI	PR:Q99ML0	Mouse	PMID:29916806
Molecular Function	GO:0044183	protein folding chaperone	FKBP8	IMP		Human	PMID:29916806
Molecular Function	GO:0044183	protein folding chaperone	Fkbp8	IMP		Mouse	PMID:29916806
Cellular Component	GO:0005829	cytosol	FKBP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	FKBP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Fkbp8	IDA		Mouse	PMID:15105374
Cellular Component	GO:0016020	membrane	FKBP8	HDA		Human	PMID:19946888
Cellular Component	GO:0005740	mitochondrial envelope	Fkbp8	IDA		Mouse	PMID:15105374
Cellular Component	GO:0005739	mitochondrion	FKBP8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Fkbp8	HDA		Mouse	PMID:18614015
Cellular Component	GO:0032991	protein-containing complex	FKBP8	IMP		Human	PMID:15733859
Biological Process	GO:0006915	apoptotic process	Fkbp8	IMP	MGI:MGI:3775614	Mouse	PMID:18003640
Biological Process	GO:0030509	BMP signaling pathway	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:18590716
Biological Process	GO:0043010	camera-type eye development	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:15105374
Biological Process	GO:0001708	cell fate specification	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Fkbp8	IGI	MGI:MGI:107689	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Fkbp8	IGI	MGI:MGI:95728	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Fkbp8	IMP	MGI:MGI:3775614	Mouse	PMID:18003640
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Fkbp8	IDA		Mouse	PMID:18590716
Biological Process	GO:0009953	dorsal/ventral pattern formation	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:15105374
Biological Process	GO:0035264	multicellular organism growth	Fkbp8	IGI	MGI:MGI:108075	Mouse	PMID:18590716
Biological Process	GO:0043066	negative regulation of apoptotic process	Fkbp8	IMP	MGI:MGI:3775614	Mouse	PMID:18003640
Biological Process	GO:0001933	negative regulation of protein phosphorylation	FKBP8	IMP		Human	PMID:15733859
Biological Process	GO:0021915	neural tube development	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:18590716
Biological Process	GO:0048665	neuron fate specification	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:15105374
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:18590716
Biological Process	GO:0006457	protein folding	FKBP8	IMP		Human	PMID:29916806
Biological Process	GO:0006457	protein folding	Fkbp8	IMP		Mouse	PMID:29916806
Biological Process	GO:0070585	protein localization to mitochondrion	FKBP8	IPI	UniProtKB:Q9GZQ8	Human	PMID:31908024
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	FKBP8	IDA		Human	PMID:28381481
Biological Process	GO:1903146	regulation of autophagy of mitochondrion	FKBP8	IDA		Human	PMID:31908024
Biological Process	GO:0030510	regulation of BMP signaling pathway	Fkbp8	IGI	MGI:MGI:95728	Mouse	PMID:18590716
Biological Process	GO:0010468	regulation of gene expression	Fkbp8	IGI	MGI:MGI:108075	Mouse	PMID:18590716
Biological Process	GO:0007224	smoothened signaling pathway	Fkbp8	IMP	MGI:MGI:3042750	Mouse	PMID:15105374
Biological Process	GO:0007224	smoothened signaling pathway	Fkbp8	IGI	MGI:MGI:98297	Mouse	PMID:15105374

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern