Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLG2
  • Mouse genes Flg2
  • Rat genes Flg2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Cellular Component	GO:0001533	cornified envelope	Flg2	IDA		Mouse	PMID:26644517
Cellular Component	GO:0005737	cytoplasm	FLG2	IDA		Human	PMID:19384417
Cellular Component	GO:0005634	nucleus	FLG2	HDA		Human	PMID:21630459
Biological Process	GO:0007155	cell adhesion	FLG2	IMP		Human	PMID:29758285
Biological Process	GO:0048730	epidermis morphogenesis	FLG2	IMP		Human	PMID:29505760
Biological Process	GO:0048730	epidermis morphogenesis	FLG2	IMP		Human	PMID:29758285
Biological Process	GO:0061436	establishment of skin barrier	FLG2	IEP		Human	PMID:23403047

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern