Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLII
  • Mouse genes Flii
  • Rat genes Flii
  • Zfish genes flii
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flii

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	FLII	IDA		Human	PMID:9525888
Molecular Function	GO:0005515	protein binding	FLII	IPI	UniProtKB:Q32MZ4	Human	PMID:10366446
Molecular Function	GO:0005515	protein binding	FLII	IPI	UniProtKB:Q9Y608	Human	PMID:10366446
Molecular Function	GO:0005515	protein binding	FLII	IPI	UniProtKB:Q32MZ4	Human	PMID:9671805
Molecular Function	GO:0005515	protein binding	Flii	IPI	UniProtKB:Q6PHZ2	Mouse	MGI:MGI:5512959|PMID:18588881
Molecular Function	GO:0005515	protein binding	Flii	IPI	PR:Q3UZ39	Mouse	PMID:19265123
Molecular Function	GO:0005515	protein binding	Flii	IPI	PR:Q91WK0	Mouse	PMID:19265123
Molecular Function	GO:0005515	protein binding	Flii	IPI	PR:P22366	Mouse	PMID:19265123
Cellular Component	GO:0005903	brush border	Flii	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0034451	centriolar satellite	FLII	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	FLII	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FLII	IDA		Human	GO_REF:0000052
Biological Process	GO:0007275	multicellular organism development	Flii	IMP	MGI:MGI:2179825	Mouse	PMID:11971982
Biological Process	GO:0045214	sarcomere organization	flii	IMP	ZFIN:ZDB-GENO-110831-1	Zfish	PMID:21554867

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern