Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLNB
  • Mouse genes Flnb
  • Rat genes Flnb
  • Zfish genes flnb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flnb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	FLNB	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	FLNB	IPI	UniProtKB:O75369	Human	PMID:12393796
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:O14640	Human	PMID:10644691
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:O14641	Human	PMID:10644691
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P05556	Human	PMID:10676904
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P21333	Human	PMID:12393796
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P62993	Human	PMID:12577067
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:Q9NP98	Human	PMID:16076904
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:Q9UBF9	Human	PMID:16076904
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P05161	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:P63000	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:Q13233	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	FLNB	IPI	UniProtKB:Q9Y6R4	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	Flnb	IPI	PR:Q7TS73	Mouse	PMID:24436304
Molecular Function	GO:0005515	protein binding	Flnb	IPI	PR:Q8BTM8	Mouse	PMID:12393796
Molecular Function	GO:0005515	protein binding	Flnb	IPI	PR:Q5SVD0	Mouse	PMID:24436304
Molecular Function	GO:0003723	RNA binding	FLNB	HDA		Human	PMID:22681889
Cellular Component	GO:0005903	brush border	Flnb	IDA		Mouse	MGI:MGI:5621262|PMID:22114352
Cellular Component	GO:0005737	cytoplasm	FLNB	HDA		Human	PMID:16791210
Cellular Component	GO:0005829	cytosol	FLNB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	FLNB	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FLNB	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	FLNB	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Flnb	IDA		Mouse	PMID:11807098
Cellular Component	GO:0043005	neuron projection	Flnb	IDA		Rat	PMID:12393796|RGD:12791264
Cellular Component	GO:0043025	neuronal cell body	Flnb	IDA		Rat	PMID:12393796|RGD:12791264
Cellular Component	GO:0005634	nucleus	Flnb	IDA		Rat	PMID:12393796|RGD:12791264
Cellular Component	GO:0045335	phagocytic vesicle	Flnb	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005886	plasma membrane	FLNB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001725	stress fiber	Flnb	IDA		Mouse	PMID:11807098
Biological Process	GO:0030036	actin cytoskeleton organization	Flnb	IMP		Mouse	PMID:24012369
Biological Process	GO:0071346	cellular response to type II interferon	Flnb	IDA		Mouse	PMID:19144319
Biological Process	GO:0003382	epithelial cell morphogenesis	Flnb	IMP		Mouse	PMID:24012369
Biological Process	GO:0003334	keratinocyte development	Flnb	IMP		Mouse	PMID:24012369
Biological Process	GO:0007519	skeletal muscle tissue development	Flnb	IDA		Mouse	PMID:11807098

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern