Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Flrt3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FLRT3
- Mouse genes Flrt3
- Rat genes Flrt3
- Zfish genes flrt3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flrt3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045499	chemorepellent activity	Flrt3	IDA		Mouse	PMID:21673655
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	Flrt3	IPI	UniProtKB:P16092	Mouse	MGI:MGI:3662950\|PMID:16872596
Molecular Function	GO:0005515	protein binding	FLRT3	IPI	UniProtKB:Q8IZJ1	Human	PMID:26235030
Molecular Function	GO:0005515	protein binding	FLRT3	IPI	UniProtKB:Q8K1S2	Human	PMID:26235030
Molecular Function	GO:0005515	protein binding	FLRT3	IPI	UniProtKB:Q9HAR2	Human	PMID:26235030
Molecular Function	GO:0005515	protein binding	FLRT3	IPI	UniProtKB:P05067-4	Human	PMID:26960425
Molecular Function	GO:0005515	protein binding	Flrt3	IPI	UniProtKB:Q80TS3	Mouse	MGI:MGI:5693672\|PMID:26235031
Molecular Function	GO:0005515	protein binding	Flrt3	IPI	UniProtKB:P12023	Mouse	MGI:MGI:6274968\|PMID:26960425
Molecular Function	GO:0005515	protein binding	Flrt3	IPI	PR:Q8K1S3	Mouse	PMID:21673655
Molecular Function	GO:0005515	protein binding	flrt3	IPI	UniProtKB:A4JYD4	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	flrt3	IPI	UniProtKB:A4JYH4	Zfish	PMID:19765300
Molecular Function	GO:0005515	protein binding	flrt3	IPI	UniProtKB:A4JYG3	Zfish	PMID:19765300
Molecular Function	GO:0042803	protein homodimerization activity	FLRT3	IDA		Human	PMID:26235030
Cellular Component	GO:0043679	axon terminus	Flrt3	IDA		Rat	PMID:15485775\|RGD:1579783
Cellular Component	GO:0044295	axonal growth cone	Flrt3	IDA		Mouse	MGI:MGI:5688822\|PMID:24560577
Cellular Component	GO:0030054	cell junction	FLRT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005911	cell-cell junction	Flrt3	IDA		Mouse	MGI:MGI:3662950\|PMID:16872596
Cellular Component	GO:0005911	cell-cell junction	Flrt3	IDA		Mouse	MGI:MGI:5688833\|PMID:22405201
Cellular Component	GO:0005829	cytosol	FLRT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005615	extracellular space	Flrt3	IDA		Mouse	PMID:21673655
Cellular Component	GO:0005925	focal adhesion	Flrt3	IDA		Mouse	MGI:MGI:3662950\|PMID:16872596
Cellular Component	GO:0098978	glutamatergic synapse	Flrt3	IDA		Mouse	PMID:22405201
Cellular Component	GO:0098978	glutamatergic synapse	Flrt3	IMP		Mouse	PMID:22405201
Cellular Component	GO:0098978	glutamatergic synapse	Flrt3	IEP		Mouse	PMID:22405201
Cellular Component	GO:0005886	plasma membrane	FLRT3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FLRT3	IDA		Human	PMID:14706654
Cellular Component	GO:0005886	plasma membrane	FLRT3	IDA		Human	PMID:26235030
Cellular Component	GO:0005886	plasma membrane	Flrt3	IDA		Mouse	MGI:MGI:5688833\|PMID:22405201
Cellular Component	GO:0005886	plasma membrane	Flrt3	IDA		Mouse	MGI:MGI:5688822\|PMID:24560577
Cellular Component	GO:0005886	plasma membrane	Flrt3	IDA		Mouse	MGI:MGI:3662950\|PMID:16872596
Cellular Component	GO:0005886	plasma membrane	Flrt3	IDA		Rat	PMID:15485775\|RGD:1579783
Cellular Component	GO:0014069	postsynaptic density	Flrt3	IDA		Rat	PMID:22405201\|RGD:12050131
Cellular Component	GO:0045211	postsynaptic membrane	Flrt3	IDA		Mouse	PMID:22405201
Cellular Component	GO:0045211	postsynaptic membrane	Flrt3	IMP		Mouse	PMID:22405201
Cellular Component	GO:0045211	postsynaptic membrane	Flrt3	IEP		Mouse	PMID:22405201
Cellular Component	GO:0045211	postsynaptic membrane	Flrt3	IDA		Rat	PMID:22405201\|RGD:12050131
Cellular Component	GO:0097060	synaptic membrane	Flrt3	IDA		Rat	PMID:15485775\|RGD:1579783
Biological Process	GO:0007411	axon guidance	Flrt3	IMP		Mouse	MGI:MGI:5688822\|PMID:24560577
Biological Process	GO:0007411	axon guidance	Flrt3	IGI	UniProtKB:O08722	Rat	PMID:21673655\|RGD:8554719
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	FLRT3	IDA		Human	PMID:26235030
Biological Process	GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	Flrt3	IMP		Mouse	MGI:MGI:5688833\|PMID:22405201
Biological Process	GO:0048598	embryonic morphogenesis	Flrt3	IMP		Mouse	MGI:MGI:3796818\|PMID:18448090
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Flrt3	IMP		Mouse	MGI:MGI:3662950\|PMID:16872596
Biological Process	GO:0060322	head development	Flrt3	IMP		Mouse	MGI:MGI:3796818\|PMID:18448090
Biological Process	GO:0007507	heart development	Flrt3	IMP		Mouse	MGI:MGI:3796818\|PMID:18448090
Biological Process	GO:0031175	neuron projection development	Flrt3	IMP		Mouse	MGI:MGI:5688833\|PMID:22405201
Biological Process	GO:0031175	neuron projection development	Flrt3	IMP		Rat	PMID:15485775\|RGD:1579783
Biological Process	GO:1990138	neuron projection extension	FLRT3	IMP		Human	PMID:14706654
Biological Process	GO:1990138	neuron projection extension	Flrt3	IMP		Rat	PMID:15485775\|RGD:1579783
Biological Process	GO:0051965	positive regulation of synapse assembly	Flrt3	IDA		Mouse	PMID:24613359
Biological Process	GO:0003345	proepicardium cell migration involved in pericardium morphogenesis	Flrt3	IMP		Mouse	MGI:MGI:3796818\|PMID:18448090
Biological Process	GO:0048678	response to axon injury	Flrt3	IMP		Rat	PMID:15485775\|RGD:1579783
Biological Process	GO:0007416	synapse assembly	Flrt3	IMP		Mouse	MGI:MGI:5688833\|PMID:22405201
Biological Process	GO:0050808	synapse organization	Flrt3	IMP		Rat	PMID:22405201\|RGD:12050131
Biological Process	GO:0099560	synaptic membrane adhesion	Flrt3	IDA		Mouse	PMID:22405201
Biological Process	GO:0099560	synaptic membrane adhesion	Flrt3	IMP		Mouse	PMID:22405201

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.