Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FLT3LG
  • Mouse genes Flt3l
  • Rat genes Flt3lg
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Flt3l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FLT3LG	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Flt3l	IDA		Mouse	PMID:7531700
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Flt3l	IPI	PR:Q00342	Mouse	PMID:7505204
Cellular Component	GO:0009986	cell surface	Flt3l	IDA		Mouse	PMID:7630197
Cellular Component	GO:0009897	external side of plasma membrane	Flt3l	IDA		Mouse	PMID:7505204
Cellular Component	GO:0005615	extracellular space	Flt3l	IDA		Mouse	PMID:7505204
Biological Process	GO:0035162	embryonic hemopoiesis	FLT3LG	IDA		Human	PMID:21149635
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Flt3l	IGI	MGI:MGI:97799	Mouse	PMID:21048959
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Flt3l	IDA		Mouse	PMID:21048959
Biological Process	GO:0030098	lymphocyte differentiation	Flt3l	IMP	MGI:MGI:2158499	Mouse	PMID:12387740
Biological Process	GO:0001779	natural killer cell differentiation	Flt3l	IMP	MGI:MGI:2158499	Mouse	PMID:14607906
Biological Process	GO:0071866	negative regulation of apoptotic process in bone marrow cell	Flt3l	IGI	MGI:MGI:97799	Mouse	PMID:21048959
Biological Process	GO:0045787	positive regulation of cell cycle	Flt3l	IDA		Mouse	PMID:21048959
Biological Process	GO:0008284	positive regulation of cell population proliferation	FLT3LG	IDA		Human	PMID:8180375
Biological Process	GO:0008284	positive regulation of cell population proliferation	Flt3l	IDA		Mouse	PMID:7505204
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	Flt3l	IGI	MGI:MGI:97799	Mouse	PMID:21048959
Biological Process	GO:0071864	positive regulation of cell proliferation in bone marrow	Flt3l	IGI	MGI:MGI:96559	Mouse	PMID:21048959
Biological Process	GO:0045663	positive regulation of myoblast differentiation	Flt3l	IMP		Mouse	PMID:23844157
Biological Process	GO:1901741	positive regulation of myoblast fusion	Flt3l	IMP		Mouse	PMID:23844157
Biological Process	GO:0032825	positive regulation of natural killer cell differentiation	Flt3l	IMP	MGI:MGI:2158499	Mouse	PMID:14607906
Biological Process	GO:0032819	positive regulation of natural killer cell proliferation	Flt3lg	IDA		Rat	PMID:16528542|RGD:11049499
Biological Process	GO:0090290	positive regulation of osteoclast proliferation	Flt3l	IGI	MGI:MGI:97799	Mouse	PMID:21048959
Biological Process	GO:0090290	positive regulation of osteoclast proliferation	Flt3l	IDA		Mouse	PMID:21048959
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Flt3l	IGI	MGI:MGI:1344336	Mouse	PMID:20360400
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Flt3l	IGI	MGI:MGI:95559	Mouse	PMID:20360400
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Flt3l	IDA		Mouse	PMID:21048959
Biological Process	GO:0006468	protein phosphorylation	Flt3l	IGI	MGI:MGI:95559	Mouse	PMID:20360400
Biological Process	GO:0006468	protein phosphorylation	Flt3l	IGI	MGI:MGI:1344336	Mouse	PMID:20360400
Biological Process	GO:0030885	regulation of myeloid dendritic cell activation	Flt3l	IMP	MGI:MGI:2158499	Mouse	PMID:23913046

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern