Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMN2
  • Mouse genes Fmn2
  • Rat genes Fmn2
  • Zfish genes fmn2a,fmn2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmn2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	FMN2	IDA		Human	PMID:20082305
Cellular Component	GO:0015629	actin cytoskeleton	FMN2	IDA		Human	PMID:20082305
Cellular Component	GO:0005938	cell cortex	Fmn2	IDA		Mouse	MGI:MGI:5305386|PMID:21983562
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	Fmn2	IDA		Mouse	MGI:MGI:5305386|PMID:21983562
Cellular Component	GO:0005829	cytosol	FMN2	IDA		Human	PMID:20082305
Cellular Component	GO:0005783	endoplasmic reticulum	Fmn2	IDA		Mouse	MGI:MGI:6467696|PMID:28992324
Cellular Component	GO:0005783	endoplasmic reticulum	Fmn2	IDA		Mouse	PMID:23439682
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Fmn2	IDA		Mouse	PMID:23439682
Cellular Component	GO:0005902	microvillus	Fmn2	IDA		Mouse	PMID:23439682
Cellular Component	GO:0005730	nucleolus	FMN2	IDA		Human	PMID:23375502
Cellular Component	GO:0005634	nucleus	FMN2	IDA		Human	PMID:26287480
Cellular Component	GO:0005819	spindle	Fmn2	IDA		Mouse	PMID:23439682
Biological Process	GO:0031532	actin cytoskeleton reorganization	FMN2	IMP		Human	PMID:24223803
Biological Process	GO:0051017	actin filament bundle assembly	Fmn2	IMP		Mouse	PMID:23439682
Biological Process	GO:0016477	cell migration	FMN2	IMP		Human	PMID:24223803
Biological Process	GO:0071456	cellular response to hypoxia	FMN2	IMP		Human	PMID:23375502
Biological Process	GO:0006974	DNA damage response	FMN2	IMP		Human	PMID:23375502
Biological Process	GO:0006974	DNA damage response	FMN2	IDA		Human	PMID:26287480
Biological Process	GO:0051295	establishment of meiotic spindle localization	Fmn2	IMP		Mouse	MGI:MGI:2448435|PMID:12447394
Biological Process	GO:0051295	establishment of meiotic spindle localization	Fmn2	IMP		Mouse	MGI:MGI:5050782|PMID:21620703
Biological Process	GO:0070649	formin-nucleated actin cable assembly	FMN2	IDA		Human	PMID:26287480
Biological Process	GO:0070649	formin-nucleated actin cable assembly	Fmn2	IMP		Mouse	MGI:MGI:5050782|PMID:21620703
Biological Process	GO:0051758	homologous chromosome movement towards spindle pole in meiosis I anaphase	Fmn2	IMP		Mouse	MGI:MGI:2448435|PMID:12447394
Biological Process	GO:0046907	intracellular transport	Fmn2	IMP		Mouse	MGI:MGI:5305386|PMID:21983562
Biological Process	GO:0016344	meiotic chromosome movement towards spindle pole	Fmn2	IMP		Mouse	PMID:23439682
Biological Process	GO:0043066	negative regulation of apoptotic process	FMN2	IMP		Human	PMID:23375502
Biological Process	GO:0042177	negative regulation of protein catabolic process	FMN2	IMP		Human	PMID:23375502
Biological Process	GO:0048477	oogenesis	Fmn2	IMP		Mouse	MGI:MGI:2448435|PMID:12447394
Biological Process	GO:0040038	polar body extrusion after meiotic divisions	Fmn2	IMP		Mouse	MGI:MGI:2448435|PMID:12447394
Biological Process	GO:2000781	positive regulation of double-strand break repair	FMN2	IDA		Human	PMID:26287480
Biological Process	GO:0016192	vesicle-mediated transport	Fmn2	IMP		Mouse	MGI:MGI:5305386|PMID:21983562

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern