Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMNL1
  • Mouse genes Fmnl1
  • Rat genes Fmnl1
  • Zfish genes fmnl1a,fmnl1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmnl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Molecular Function	GO:0032794	GTPase activating protein binding	FMNL1	IDA		Human	PMID:21148482
Molecular Function	GO:0032794	GTPase activating protein binding	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Molecular Function	GO:0005522	profilin binding	Fmnl1	IDA		Mouse	PMID:10958683
Molecular Function	GO:0005515	protein binding	FMNL1	IPI	UniProtKB:O75044	Human	PMID:21148482
Molecular Function	GO:0005515	protein binding	FMNL1	IPI	UniProtKB:D0ZIB5	Human	PMID:34237247
Molecular Function	GO:0005515	protein binding	Fmnl1	IPI	UniProtKB:D0ZIB5	Mouse	MGI:MGI:6810806|PMID:34237247
Molecular Function	GO:0031267	small GTPase binding	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Cellular Component	GO:0005829	cytosol	FMNL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Cellular Component	GO:0005829	cytosol	Fmnl1	IDA		Mouse	PMID:10958683
Cellular Component	GO:0070062	extracellular exosome	FMNL1	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	FMNL1	HDA		Human	PMID:19946888
Cellular Component	GO:0045335	phagocytic vesicle	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Cellular Component	GO:0005886	plasma membrane	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Biological Process	GO:0051014	actin filament severing	Fmnl1	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Biological Process	GO:0030866	cortical actin cytoskeleton organization	FMNL1	IMP		Human	PMID:21834987
Biological Process	GO:0008360	regulation of cell shape	FMNL1	IMP		Human	PMID:21834987
Biological Process	GO:0006929	substrate-dependent cell migration	Fmnl1	IMP		Mouse	PMID:10958683

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern