Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMNL2
  • Mouse genes Fmnl2
  • Rat genes Fmnl2
  • Zfish genes fmnl2a,fmnl2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmnl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	FMNL2	HDA		Human	PMID:25468996
Biological Process	GO:0030866	cortical actin cytoskeleton organization	FMNL2	IMP		Human	PMID:21834987
Biological Process	GO:0007010	cytoskeleton organization	FMNL2	IMP		Human	PMID:21834987
Biological Process	GO:0060857	establishment of glial blood-brain barrier	fmnl2b	IMP	ZFIN:ZDB-MRPHLNO-150420-4	Zfish	PMID:35608697
Biological Process	GO:0060857	establishment of glial blood-brain barrier	fmnl2a	IMP	ZFIN:ZDB-MRPHLNO-150420-3	Zfish	PMID:35608697
Biological Process	GO:0022604	regulation of cell morphogenesis	FMNL2	IMP		Human	PMID:21834987

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern