Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMNL3
  • Mouse genes Fmnl3
  • Rat genes Fmnl3
  • Zfish genes fmnl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmnl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032794	GTPase activating protein binding	Fmnl3	IDA		Mouse	MGI:MGI:5426775|PMID:21148482
Molecular Function	GO:0005515	protein binding	Fmnl3	IPI	UniProtKB:P68135	Mouse	MGI:MGI:5917797|PMID:23222643
Molecular Function	GO:0005515	protein binding	Fmnl3	IPI	PR:Q9R1C7	Mouse	PMID:9171351
Molecular Function	GO:0005515	protein binding	fmnl3	IPI	ZFIN:ZDB-GENE-030131-1571	Zfish	PMID:25584797
Molecular Function	GO:0005515	protein binding	fmnl3	IPI	ZFIN:ZDB-GENE-030131-8783	Zfish	PMID:25584797
Cellular Component	GO:0005737	cytoplasm	FMNL3	IDA		Human	PMID:21834987
Cellular Component	GO:0005829	cytosol	FMNL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	FMNL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	FMNL3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FMNL3	IDA		Human	GO_REF:0000052
Biological Process	GO:0031532	actin cytoskeleton reorganization	FMNL3	IMP		Human	PMID:24223803
Biological Process	GO:0030041	actin filament polymerization	fmnl3	IDA		Zfish	PMID:25584797
Biological Process	GO:0001525	angiogenesis	fmnl3	IMP	ZFIN:ZDB-MRPHLNO-120503-2	Zfish	PMID:22275430
Biological Process	GO:0016477	cell migration	FMNL3	IMP		Human	PMID:21834987
Biological Process	GO:0016477	cell migration	FMNL3	IMP		Human	PMID:24223803
Biological Process	GO:0007010	cytoskeleton organization	FMNL3	IMP		Human	PMID:21834987
Biological Process	GO:0046847	filopodium assembly	FMNL3	IDA		Human	PMID:24223803
Biological Process	GO:0046847	filopodium assembly	fmnl3	IMP	ZFIN:ZDB-MRPHLNO-120503-2	Zfish	PMID:25584797
Biological Process	GO:0008360	regulation of cell shape	FMNL3	IMP		Human	PMID:21834987
Biological Process	GO:0002040	sprouting angiogenesis	fmnl3	IGI	ZFIN:ZDB-GENE-030131-7745	Zfish	PMID:25584797
Biological Process	GO:0002040	sprouting angiogenesis	fmnl3	IGI	ZFIN:ZDB-GENE-070618-1,ZFIN:ZDB-GENE-070618-2	Zfish	PMID:25584797
Biological Process	GO:0002040	sprouting angiogenesis	fmnl3	IMP	ZFIN:ZDB-MRPHLNO-120503-2	Zfish	PMID:25584797

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern