Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMO1
  • Mouse genes Fmo1
  • Rat genes Fmo1
  • Zfish genes fmo5,si:dkey-239i20.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047822	hypotaurine dehydrogenase activity	FMO1	EXP		Human	PMID:32156684
Molecular Function	GO:0047822	hypotaurine dehydrogenase activity	FMO1	IDA		Human	PMID:32156684
Molecular Function	GO:0047822	hypotaurine dehydrogenase activity	Fmo1	IMP		Mouse	MGI:MGI:6881635|PMID:32156684
Molecular Function	GO:0004497	monooxygenase activity	FMO1	IDA		Human	PMID:19262426
Molecular Function	GO:0004497	monooxygenase activity	Fmo1	IMP	MGI:MGI:5487815	Mouse	PMID:19262426
Molecular Function	GO:0004497	monooxygenase activity	Fmo1	IDA		Rat	PMID:8504165|RGD:728615
Molecular Function	GO:0004499	N,N-dimethylaniline monooxygenase activity	FMO1	IDA		Human	PMID:15144220
Molecular Function	GO:0004499	N,N-dimethylaniline monooxygenase activity	Fmo1	IDA		Rat	PMID:8504165|RGD:728615
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:Q5SR56	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:Q7Z429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO1	IPI	UniProtKB:Q9H6H4	Human	PMID:32296183
Molecular Function	GO:0034899	trimethylamine monooxygenase activity	Fmo1	IDA		Rat	PMID:8504165|RGD:728615
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Fmo1	IDA		Rat	PMID:19307449|RGD:2316309
Biological Process	GO:0097009	energy homeostasis	Fmo1	IGI	MGI:1916776,MGI:2429497	Mouse	PMID:24792439
Biological Process	GO:0070995	NADPH oxidation	FMO1	IDA		Human	PMID:15144220
Biological Process	GO:0046322	negative regulation of fatty acid oxidation	Fmo1	IGI	MGI:1916776,MGI:2429497	Mouse	PMID:24792439
Biological Process	GO:0006082	organic acid metabolic process	FMO1	IDA		Human	PMID:15144220
Biological Process	GO:0032496	response to lipopolysaccharide	Fmo1	IEP		Rat	PMID:19779138|RGD:2316301
Biological Process	GO:0006970	response to osmotic stress	Fmo1	IEP		Rat	PMID:19429252|RGD:2316303
Biological Process	GO:0042412	taurine biosynthetic process	FMO1	IDA		Human	PMID:32156684
Biological Process	GO:0042412	taurine biosynthetic process	Fmo1	IMP		Mouse	MGI:MGI:6881635|PMID:32156684
Biological Process	GO:0009404	toxin metabolic process	FMO1	IDA		Human	PMID:15144220
Biological Process	GO:0006805	xenobiotic metabolic process	Fmo1	IMP	MGI:MGI:5487815	Mouse	PMID:19262426

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern