Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FMO3
  • Mouse genes Fmo3
  • Rat genes Fmo3
  • Zfish genes fmo5,si:dkey-239i20.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmo3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Fmo3	IPI	PubChem_Compound:105024	Rat	PMID:17173378|RGD:1626480
Molecular Function	GO:0047822	hypotaurine dehydrogenase activity	FMO3	IDA		Human	PMID:32156684
Molecular Function	GO:0004499	N,N-dimethylaniline monooxygenase activity	Fmo3	IDA		Rat	PMID:17173378|RGD:1626480
Molecular Function	GO:0004499	N,N-dimethylaniline monooxygenase activity	Fmo3	IDA		Rat	PMID:18775983|RGD:2325184
Molecular Function	GO:0050661	NADP binding	Fmo3	IPI	CHEBI:16474	Rat	PMID:17173378|RGD:1626480
Molecular Function	GO:0005515	protein binding	FMO3	IPI	UniProtKB:O43889-2	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FMO3	IPI	UniProtKB:O43889-2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FMO3	IPI	UniProtKB:Q8IUN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO3	IPI	UniProtKB:Q96HU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FMO3	IPI	UniProtKB:Q9NTJ5	Human	PMID:32296183
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Fmo3	IDA		Rat	PMID:11414682|RGD:632683
Biological Process	GO:0042412	taurine biosynthetic process	FMO3	IDA		Human	PMID:32156684
Biological Process	GO:0006805	xenobiotic metabolic process	Fmo3	IDA		Rat	PMID:17173378|RGD:1626480

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern