Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Fmr1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FMR1
- Mouse genes Fmr1
- Rat genes Fmr1
- Zfish genes fmr1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fmr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Fmr1	IDA		Mouse	MGI:MGI:5602914\|PMID:24813610
Molecular Function	GO:0003677	DNA binding	FMR1	EXP		Human	PMID:10496225
Molecular Function	GO:0070840	dynein complex binding	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Molecular Function	GO:0002151	G-quadruplex RNA binding	FMR1	IDA		Human	PMID:18653529
Molecular Function	GO:0002151	G-quadruplex RNA binding	FMR1	IDA		Human	PMID:25464849
Molecular Function	GO:0042802	identical protein binding	FMR1	IDA		Human	PMID:11157796
Molecular Function	GO:0042802	identical protein binding	FMR1	IPI	UniProtKB:Q06787	Human	PMID:17850748
Molecular Function	GO:0042802	identical protein binding	FMR1	IPI	UniProtKB:Q06787	Human	PMID:21446998
Molecular Function	GO:0042802	identical protein binding	FMR1	IPI	UniProtKB:Q06787	Human	PMID:31413325
Molecular Function	GO:0035064	methylated histone binding	FMR1	IDA		Human	PMID:24813610
Molecular Function	GO:0008017	microtubule binding	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Molecular Function	GO:0008017	microtubule binding	Fmr1	IDA		Mouse	PMID:17881655
Molecular Function	GO:0035198	miRNA binding	FMR1	IDA		Human	PMID:17057366
Molecular Function	GO:0035198	miRNA binding	Fmr1	IDA		Mouse	MGI:MGI:4868681\|PMID:20159450
Molecular Function	GO:0140693	molecular condensate scaffold activity	FMR1	IDA		Human	PMID:30765518
Molecular Function	GO:0140693	molecular condensate scaffold activity	FMR1	EXP		Human	PMID:31439799
Molecular Function	GO:0140693	molecular condensate scaffold activity	FMR1	IDA		Human	PMID:31439799
Molecular Function	GO:0003730	mRNA 3'-UTR binding	FMR1	IDA		Human	PMID:17417632
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Fmr1	IDA		Mouse	MGI:MGI:2684495\|PMID:14613971
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Fmr1	IDA		Mouse	MGI:MGI:5767073\|PMID:11376146
Molecular Function	GO:0048027	mRNA 5'-UTR binding	FMR1	IDA		Human	PMID:19166269
Molecular Function	GO:0003729	mRNA binding	FMR1	IDA		Human	PMID:11157796
Molecular Function	GO:0003729	mRNA binding	FMR1	IDA		Human	PMID:18936162
Molecular Function	GO:0003729	mRNA binding	FMR1	IDA		Human	PMID:25561520
Molecular Function	GO:0003729	mRNA binding	FMR1	IDA		Human	PMID:30765518
Molecular Function	GO:0003729	mRNA binding	FMR1	IDA		Human	PMID:31439799
Molecular Function	GO:0003729	mRNA binding	Fmr1	IDA		Mouse	MGI:MGI:2684495\|PMID:14613971
Molecular Function	GO:0003729	mRNA binding	Fmr1	IPI	RGD:3165	Rat	PMID:24338128\|RGD:11667958
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	FMR1	IDA		Human	PMID:31753916
Molecular Function	GO:1990247	N6-methyladenosine-containing RNA binding	Fmr1	IDA		Mouse	PMID:31340148
Molecular Function	GO:0034046	poly(G) binding	FMR1	IDA		Human	PMID:7688265
Molecular Function	GO:0008266	poly(U) RNA binding	FMR1	IDA		Human	PMID:7688265
Molecular Function	GO:0008266	poly(U) RNA binding	FMR1	IDA		Human	PMID:8156595
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q9QXX8	Human	PMID:10556305
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q9UHK0	Human	PMID:10556305
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:11157796
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51116	Human	PMID:11157796
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q7L576	Human	PMID:11438699
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q96F07	Human	PMID:11438699
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q7Z417	Human	PMID:12837692
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P05388	Human	PMID:15380484
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:15380484
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q96S59	Human	PMID:15381419
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q7Z417	Human	PMID:16407062
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q96EZ8	Human	PMID:16571602
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q16637	Human	PMID:18093976
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q9UBU9	Human	PMID:18936162
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51116	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q5JVS0	Human	PMID:21771594
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P03466	Human	PMID:24514761
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P19338	Human	PMID:24658146
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q96F07	Human	PMID:24658146
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51116	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q13835	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q9Y446	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q9HCE1	Human	PMID:25464849
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:O00154	Human	PMID:26949739
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:26949739
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51116	Human	PMID:26949739
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:Q14444	Human	PMID:31439799
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51114	Human	PMID:7489725
Molecular Function	GO:0005515	protein binding	FMR1	IPI	UniProtKB:P51116	Human	PMID:7489725
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P23249	Mouse	MGI:MGI:5780533\|PMID:25464849
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P62960	Mouse	MGI:MGI:5767075\|PMID:11162447
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:Q3UNA4	Mouse	MGI:MGI:5770077\|PMID:16790844
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P54282\|UniProtKB:Q05152	Mouse	MGI:MGI:5770038\|PMID:24709664
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:Q5SQX6\|UniProtKB:Q7TMB8	Mouse	MGI:MGI:3036554\|PMID:11438699
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:Q7TMB8	Mouse	MGI:MGI:4418608\|PMID:18805096
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P69566	Mouse	MGI:MGI:5763380\|PMID:15381419
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P33175	Mouse	MGI:MGI:3798322\|PMID:18539120
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:Q9JHG6	Mouse	MGI:MGI:5441164\|PMID:22863780
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:P09405\|UniProtKB:Q61584\|UniProtKB:Q9WVR4	Mouse	MGI:MGI:5767076\|PMID:10567518
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	PR:O35066	Mouse	PMID:17881655
Molecular Function	GO:0005515	protein binding	Fmr1	IPI	UniProtKB:Q9R0N3	Rat	PMID:24882364\|RGD:8693368
Molecular Function	GO:0019904	protein domain specific binding	Fmr1	IDA		Rat	PMID:24882364\|RGD:8693368
Molecular Function	GO:0046982	protein heterodimerization activity	FMR1	IDA		Human	PMID:7489725
Molecular Function	GO:0042803	protein homodimerization activity	FMR1	IDA		Human	PMID:7489725
Molecular Function	GO:0019901	protein kinase binding	Fmr1	IPI	RGD:620683	Rat	PMID:23831253\|RGD:11667971
Molecular Function	GO:0019903	protein phosphatase binding	Fmr1	IDA		Rat	PMID:23831253\|RGD:11667971
Molecular Function	GO:0043022	ribosome binding	FMR1	IPI	UniProtKB:P05388	Human	PMID:24658146
Molecular Function	GO:0000340	RNA 7-methylguanosine cap binding	Fmr1	IDA		Rat	PMID:25453757\|RGD:11558007
Molecular Function	GO:0003723	RNA binding	FMR1	IMP		Human	PMID:10496225
Molecular Function	GO:0003723	RNA binding	FMR1	IDA		Human	PMID:15381419
Molecular Function	GO:0003723	RNA binding	FMR1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	FMR1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	FMR1	IMP		Human	PMID:25225333
Molecular Function	GO:0003723	RNA binding	Fmr1	IDA		Mouse	PMID:24349419
Molecular Function	GO:0003723	RNA binding	Fmr1	IDA		Rat	PMID:12417734\|RGD:628492
Molecular Function	GO:0035613	RNA stem-loop binding	FMR1	IDA		Human	PMID:15805463
Molecular Function	GO:0035613	RNA stem-loop binding	FMR1	IDA		Human	PMID:19166269
Molecular Function	GO:0033592	RNA strand annealing activity	FMR1	IDA		Human	PMID:17057366
Molecular Function	GO:1990825	sequence-specific mRNA binding	FMR1	IDA		Human	PMID:12927206
Molecular Function	GO:1990825	sequence-specific mRNA binding	FMR1	IDA		Human	PMID:23235829
Molecular Function	GO:0035591	signaling adaptor activity	FMR1	IDA		Human	PMID:31439799
Molecular Function	GO:0035197	siRNA binding	FMR1	IDA		Human	PMID:17057366
Molecular Function	GO:0031369	translation initiation factor binding	FMR1	IPI	UniProtKB:P55010	Human	PMID:24658146
Molecular Function	GO:0045182	translation regulator activity	FMR1	IDA		Human	PMID:30765518
Molecular Function	GO:0045182	translation regulator activity	FMR1	IDA		Human	PMID:31439799
Molecular Function	GO:0045182	translation regulator activity	Fmr1	IDA		Mouse	PMID:12032354
Molecular Function	GO:0045182	translation regulator activity	Fmr1	IMP		Mouse	PMID:12032354
Molecular Function	GO:0045182	translation regulator activity	Fmr1	IDA		Rat	PMID:24709664\|RGD:11059581
Molecular Function	GO:0045182	translation regulator activity	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Molecular Function	GO:0030371	translation repressor activity	FMR1	IDA		Human	PMID:11157796
Molecular Function	GO:0030371	translation repressor activity	Fmr1	IDA		Mouse	MGI:MGI:5767073\|PMID:11376146
Molecular Function	GO:0044325	transmembrane transporter binding	FMR1	IPI	UniProtKB:Q9JIN6	Human	PMID:25561520
Cellular Component	GO:0030424	axon	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0030424	axon	Fmr1	IDA		Mouse	MGI:MGI:3833000\|PMID:19193898
Cellular Component	GO:0030424	axon	Fmr1	IDA		Rat	PMID:16809002\|RGD:10043167
Cellular Component	GO:0043679	axon terminus	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0044297	cell body	Fmr1	IDA		Rat	PMID:17881655\|RGD:8553560
Cellular Component	GO:0042995	cell projection	FMR1	IDA		Human	PMID:15380484
Cellular Component	GO:0010369	chromocenter	Fmr1	IDA		Mouse	MGI:MGI:5602914\|PMID:24813610
Cellular Component	GO:0005694	chromosome	Fmr1	IDA		Mouse	MGI:MGI:5602914\|PMID:24813610
Cellular Component	GO:0005737	cytoplasm	FMR1	IDA		Human	PMID:9259278
Cellular Component	GO:0005737	cytoplasm	FMR1	IDA		Human	PMID:15381419
Cellular Component	GO:0005737	cytoplasm	FMR1	IDA		Human	PMID:16571602
Cellular Component	GO:0005737	cytoplasm	FMR1	IDA		Human	PMID:18936162
Cellular Component	GO:0005737	cytoplasm	FMR1	IDA		Human	PMID:9659908
Cellular Component	GO:0005737	cytoplasm	Fmr1	IDA		Mouse	MGI:MGI:5770077\|PMID:16790844
Cellular Component	GO:0005737	cytoplasm	Fmr1	IDA		Mouse	MGI:MGI:5770038\|PMID:24709664
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	FMR1	IDA		Human	PMID:15121898
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	FMR1	IDA		Human	PMID:15380484
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	FMR1	IDA		Human	PMID:18093976
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	Fmr1	IDA		Rat	PMID:16098134\|RGD:1601176
Cellular Component	GO:0010494	cytoplasmic stress granule	FMR1	IDA		Human	PMID:12417522
Cellular Component	GO:0010494	cytoplasmic stress granule	Fmr1	IDA		Mouse	PMID:21933836
Cellular Component	GO:0010494	cytoplasmic stress granule	Fmr1	IDA		Rat	PMID:16510718\|RGD:11667962
Cellular Component	GO:0010494	cytoplasmic stress granule	Fmr1	IDA		Rat	PMID:16919243\|RGD:10059582
Cellular Component	GO:0005829	cytosol	FMR1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Fmr1	IDA		Rat	PMID:22817682\|RGD:11566024
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Mouse	MGI:MGI:3833000\|PMID:19193898
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Mouse	PMID:22022532
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Rat	PMID:15564573\|RGD:1601175
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Rat	PMID:16571602\|RGD:9587849
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0030425	dendrite	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:1902737	dendritic filopodium	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Cellular Component	GO:1902737	dendritic filopodium	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:1902737	dendritic filopodium	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Cellular Component	GO:1902737	dendritic filopodium	Fmr1	IDA		Rat	PMID:16098134\|RGD:1601176
Cellular Component	GO:0043197	dendritic spine	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0043197	dendritic spine	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Cellular Component	GO:0043197	dendritic spine	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0043197	dendritic spine	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0044327	dendritic spine head	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Cellular Component	GO:0044326	dendritic spine neck	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Cellular Component	GO:0019897	extrinsic component of plasma membrane	Fmr1	IDA		Mouse	MGI:MGI:5770038\|PMID:24709664
Cellular Component	GO:0032433	filopodium tip	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0097386	glial cell projection	Fmr1	IDA		Rat	PMID:14613971\|RGD:11059587
Cellular Component	GO:0098978	glutamatergic synapse	Fmr1	IDA		Mouse	PMID:19193898
Cellular Component	GO:0098978	glutamatergic synapse	Fmr1	IDA		Rat	PMID:24709664\|RGD:11059581
Cellular Component	GO:0098978	glutamatergic synapse	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Cellular Component	GO:0098978	glutamatergic synapse	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0030426	growth cone	FMR1	IDA		Human	PMID:15380484
Cellular Component	GO:0030426	growth cone	Fmr1	IDA		Rat	PMID:16098134\|RGD:1601176
Cellular Component	GO:1990812	growth cone filopodium	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Fmr1	IDA		Mouse	PMID:19193898
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	FMR1	IDA		Human	PMID:30765518
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	FMR1	IDA		Human	PMID:31439799
Cellular Component	GO:0016020	membrane	FMR1	HDA		Human	PMID:19946888
Cellular Component	GO:1990124	messenger ribonucleoprotein complex	FMR1	IDA		Human	PMID:25225333
Cellular Component	GO:0015630	microtubule cytoskeleton	Fmr1	IDA		Rat	PMID:17881655\|RGD:8553560
Cellular Component	GO:0005845	mRNA cap binding complex	Fmr1	IDA		Mouse	MGI:MGI:4418608\|PMID:18805096
Cellular Component	GO:0043005	neuron projection	FMR1	IDA		Human	PMID:18093976
Cellular Component	GO:0043005	neuron projection	Fmr1	IDA		Rat	PMID:15564573\|RGD:1601175
Cellular Component	GO:0043005	neuron projection	Fmr1	IDA		Rat	PMID:24709664\|RGD:11059581
Cellular Component	GO:0043025	neuronal cell body	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	FMR1	IDA		Human	PMID:30765518
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	Fmr1	IDA		Mouse	PMID:21933836
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	Fmr1	IDA		Rat	PMID:17881655\|RGD:8553560
Cellular Component	GO:0005730	nucleolus	FMR1	IDA		Human	PMID:16571602
Cellular Component	GO:0005730	nucleolus	FMR1	IDA		Human	PMID:24658146
Cellular Component	GO:0005654	nucleoplasm	FMR1	IDA		Human	PMID:16571602
Cellular Component	GO:0005654	nucleoplasm	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0005634	nucleus	FMR1	IDA		Human	PMID:31753916
Cellular Component	GO:0005634	nucleus	FMR1	IDA		Human	PMID:18936162
Cellular Component	GO:0005634	nucleus	Fmr1	IDA		Mouse	PMID:12700164
Cellular Component	GO:0005634	nucleus	Fmr1	IDA		Rat	PMID:22817682\|RGD:11566024
Cellular Component	GO:0005634	nucleus	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0005634	nucleus	fmr1	IDA		Zfish	PMID:15818485
Cellular Component	GO:0043204	perikaryon	FMR1	IDA		Human	PMID:15380484
Cellular Component	GO:0043204	perikaryon	FMR1	IDA		Human	PMID:18093976
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Mouse	MGI:MGI:2684495\|PMID:14613971
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Mouse	MGI:MGI:3833000\|PMID:19193898
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:12112448\|RGD:11566026
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:14613971\|RGD:11059587
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:16571602\|RGD:9587849
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:24709664\|RGD:11059581
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0043204	perikaryon	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0048471	perinuclear region of cytoplasm	FMR1	IDA		Human	PMID:24658146
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Fmr1	IDA		Mouse	MGI:MGI:5770077\|PMID:16790844
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Fmr1	IDA		Rat	PMID:23831253\|RGD:11667971
Cellular Component	GO:0005844	polysome	FMR1	IDA		Human	PMID:19097999
Cellular Component	GO:0005844	polysome	FMR1	IDA		Human	PMID:25464849
Cellular Component	GO:0005844	polysome	FMR1	IDA		Human	PMID:25561520
Cellular Component	GO:0005844	polysome	FMR1	IDA		Human	PMID:9659908
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Mouse	MGI:MGI:2684495\|PMID:14613971
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Mouse	MGI:MGI:3575838\|PMID:15805463
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Rat	PMID:16098134\|RGD:1601176
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Rat	PMID:14613971\|RGD:11059587
Cellular Component	GO:0005844	polysome	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0098794	postsynapse	Fmr1	IDA		Mouse	MGI:MGI:3717507\|PMID:17254795
Cellular Component	GO:0098794	postsynapse	Fmr1	IDA		Mouse	MGI:MGI:3833000\|PMID:19193898
Cellular Component	GO:0099524	postsynaptic cytosol	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0014069	postsynaptic density	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0098793	presynapse	Fmr1	IDA		Mouse	MGI:MGI:3833000\|PMID:19193898
Cellular Component	GO:0099523	presynaptic cytosol	Fmr1	IDA		Mouse	PMID:19193898
Cellular Component	GO:1990635	proximal dendrite	Fmr1	IDA		Rat	PMID:12112448\|RGD:11566026
Cellular Component	GO:1990904	ribonucleoprotein complex	FMR1	IDA		Human	PMID:19097999
Cellular Component	GO:1990904	ribonucleoprotein complex	FMR1	IDA		Human	PMID:9659908
Cellular Component	GO:0005791	rough endoplasmic reticulum	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Fmr1	IMP		Mouse	PMID:12032354
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Fmr1	IDA		Mouse	PMID:12032354
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Cellular Component	GO:0032797	SMN complex	Fmr1	IDA		Mouse	MGI:MGI:5763366\|PMID:18093976
Cellular Component	GO:0005790	smooth endoplasmic reticulum	Fmr1	IDA		Rat	PMID:12112448\|RGD:11566026
Cellular Component	GO:0097444	spine apparatus	Fmr1	IDA		Rat	PMID:9030614\|RGD:11041080
Cellular Component	GO:0045202	synapse	Fmr1	IDA		Mouse	MGI:MGI:3655188\|PMID:16631377
Cellular Component	GO:0043195	terminal bouton	Fmr1	IDA		Rat	PMID:15028757\|RGD:1300188
Biological Process	GO:0008089	anterograde axonal transport	Fmr1	IMP		Mouse	MGI:MGI:5704269\|PMID:26586091
Biological Process	GO:0007420	brain development	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:0048755	branching morphogenesis of a nerve	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:0051216	cartilage development	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:1905232	cellular response to L-glutamate	Fmr1	IEP		Rat	PMID:22817682\|RGD:11566024
Biological Process	GO:0035865	cellular response to potassium ion	Fmr1	IEP		Rat	PMID:15028757\|RGD:1300188
Biological Process	GO:0098586	cellular response to virus	FMR1	IDA		Human	PMID:24514761
Biological Process	GO:0007417	central nervous system development	Fmr1	IMP	MGI:MGI:2451086	Mouse	PMID:12700164
Biological Process	GO:0050890	cognition	fmr1	IMP	ZFIN:ZDB-GENO-100528-8	Zfish	PMID:23536755
Biological Process	GO:0060996	dendritic spine development	Fmr1	IGI	MGI:MGI:1339656	Mouse	PMID:23509247
Biological Process	GO:0060996	dendritic spine development	Fmr1	IGI	MGI:MGI:1339975	Mouse	PMID:23509247
Biological Process	GO:0060996	dendritic spine development	Fmr1	IGI	MGI:MGI:1339984	Mouse	PMID:23509247
Biological Process	GO:0060996	dendritic spine development	Fmr1	IGI	MGI:MGI:1917834	Mouse	PMID:23509247
Biological Process	GO:0050974	detection of mechanical stimulus involved in sensory perception	Fmr1	IEP		Rat	PMID:12591163\|RGD:11570504
Biological Process	GO:0006281	DNA repair	FMR1	IDA		Human	PMID:24813610
Biological Process	GO:0006281	DNA repair	Fmr1	IDA		Mouse	MGI:MGI:5602914\|PMID:24813610
Biological Process	GO:0098976	excitatory chemical synaptic transmission	Fmr1	IMP	MGI:MGI:1857169	Mouse	PMID:30679017
Biological Process	GO:0021905	forebrain-midbrain boundary formation	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:0007215	glutamate receptor signaling pathway	Fmr1	IMP		Mouse	MGI:MGI:3710908\|PMID:17417632
Biological Process	GO:0007215	glutamate receptor signaling pathway	Fmr1	IMP		Mouse	MGI:MGI:2136541\|PMID:11438589
Biological Process	GO:0007215	glutamate receptor signaling pathway	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Biological Process	GO:0007215	glutamate receptor signaling pathway	Fmr1	IDA		Rat	PMID:9144248\|RGD:11059594
Biological Process	GO:0098977	inhibitory chemical synaptic transmission	Fmr1	IMP	MGI:MGI:1857169	Mouse	PMID:30679017
Biological Process	GO:0044830	modulation by host of viral RNA genome replication	FMR1	IMP		Human	PMID:24514761
Biological Process	GO:0006406	mRNA export from nucleus	FMR1	IDA		Human	PMID:31753916
Biological Process	GO:0006406	mRNA export from nucleus	Fmr1	IDA		Mouse	PMID:31340148
Biological Process	GO:0051028	mRNA transport	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Biological Process	GO:2000766	negative regulation of cytoplasmic translation	Fmr1	IDA		Mouse	MGI:MGI:5767073\|PMID:11376146
Biological Process	GO:0010629	negative regulation of gene expression	Fmr1	IMP		Mouse	MGI:MGI:5473740\|PMID:23235829
Biological Process	GO:0010629	negative regulation of gene expression	Fmr1	IMP		Rat	PMID:24338128\|RGD:11667958
Biological Process	GO:1900453	negative regulation of long-term synaptic depression	Fmr1	IMP		Mouse	MGI:MGI:2136541\|PMID:11438589
Biological Process	GO:1902373	negative regulation of mRNA catabolic process	FMR1	IMP		Human	PMID:25225333
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Fmr1	IMP		Rat	PMID:22817682\|RGD:11566024
Biological Process	GO:0045665	negative regulation of neuron differentiation	Fmr1	IMP		Rat	PMID:24338128\|RGD:11667958
Biological Process	GO:0010955	negative regulation of protein processing	Fmr1	IMP		Rat	PMID:22817682\|RGD:11566024
Biological Process	GO:0002091	negative regulation of receptor internalization	Fmr1	IMP		Rat	PMID:17881561\|RGD:12050150
Biological Process	GO:2000301	negative regulation of synaptic vesicle exocytosis	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Biological Process	GO:0017148	negative regulation of translation	FMR1	IDA		Human	PMID:12417522
Biological Process	GO:0017148	negative regulation of translation	FMR1	IDA		Human	PMID:30765518
Biological Process	GO:0017148	negative regulation of translation	FMR1	IDA		Human	PMID:31439799
Biological Process	GO:0017148	negative regulation of translation	Fmr1	IDA		Mouse	MGI:MGI:2684495\|PMID:14613971
Biological Process	GO:0017148	negative regulation of translation	Fmr1	IMP		Mouse	MGI:MGI:5904573\|PMID:27666021
Biological Process	GO:0045947	negative regulation of translational initiation	Fmr1	IDA		Mouse	MGI:MGI:4418608\|PMID:18805096
Biological Process	GO:1901386	negative regulation of voltage-gated calcium channel activity	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Biological Process	GO:0014036	neural crest cell fate specification	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:0048812	neuron projection morphogenesis	fmr1	IMP	ZFIN:ZDB-MRPHLNO-070108-4,ZFIN:ZDB-MRPHLNO-070108-5	Zfish	PMID:17065172
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	FMR1	IDA		Human	PMID:30765518
Biological Process	GO:0140694	non-membrane-bounded organelle assembly	FMR1	IDA		Human	PMID:31439799
Biological Process	GO:0001541	ovarian follicle development	Fmr1	IEP		Rat	PMID:23401597\|RGD:11566032
Biological Process	GO:0060999	positive regulation of dendritic spine development	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Biological Process	GO:0051491	positive regulation of filopodium assembly	Fmr1	IDA		Mouse	MGI:MGI:3798322\|PMID:18539120
Biological Process	GO:0010628	positive regulation of gene expression	Fmr1	IMP		Rat	PMID:22817682\|RGD:11566024
Biological Process	GO:1901254	positive regulation of intracellular transport of viral material	FMR1	IMP		Human	PMID:24514761
Biological Process	GO:0048170	positive regulation of long-term neuronal synaptic plasticity	Fmr1	IMP		Rat	PMID:28894415\|RGD:38501107
Biological Process	GO:1900454	positive regulation of long-term synaptic depression	Fmr1	IMP		Rat	PMID:28894415\|RGD:38501107
Biological Process	GO:1900273	positive regulation of long-term synaptic potentiation	Fmr1	IMP		Rat	PMID:28894415\|RGD:38501107
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	FMR1	IDA		Human	PMID:17057366
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	Fmr1	IDA		Mouse	MGI:MGI:4868681\|PMID:20159450
Biological Process	GO:1902416	positive regulation of mRNA binding	FMR1	IDA		Human	PMID:25464849
Biological Process	GO:1901800	positive regulation of proteasomal protein catabolic process	Fmr1	IDA		Mouse	MGI:MGI:5770038\|PMID:24709664
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Fmr1	IMP		Rat	PMID:22817682\|RGD:11566024
Biological Process	GO:0002092	positive regulation of receptor internalization	FMR1	IDA		Human	PMID:25561520
Biological Process	GO:0050806	positive regulation of synaptic transmission	Fmr1	IMP		Rat	PMID:28894415\|RGD:38501107
Biological Process	GO:0045727	positive regulation of translation	FMR1	IDA		Human	PMID:19097999
Biological Process	GO:0045727	positive regulation of translation	FMR1	IDA		Human	PMID:19166269
Biological Process	GO:0045727	positive regulation of translation	Fmr1	IMP		Mouse	MGI:MGI:3831580\|PMID:19166269
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	FMR1	IDA		Human	PMID:18653529
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Fmr1	IDA		Mouse	MGI:MGI:5009520\|PMID:18653529
Biological Process	GO:0060998	regulation of dendritic spine development	FMR1	IDA		Human	PMID:16631377
Biological Process	GO:0060998	regulation of dendritic spine development	Fmr1	IMP		Mouse	MGI:MGI:3655188\|PMID:16631377
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	fmr1	IMP	ZFIN:ZDB-GENO-230215-5	Zfish	PMID:35875841
Biological Process	GO:0051489	regulation of filopodium assembly	FMR1	IDA		Human	PMID:16631377
Biological Process	GO:0051489	regulation of filopodium assembly	Fmr1	IMP		Mouse	MGI:MGI:3655188\|PMID:16631377
Biological Process	GO:0060964	regulation of miRNA-mediated gene silencing	FMR1	IMP		Human	PMID:25464849
Biological Process	GO:1905244	regulation of modification of synaptic structure	Fmr1	IMP		Mouse	MGI:MGI:3590387\|PMID:16055059
Biological Process	GO:0090365	regulation of mRNA modification	fmr1	IMP	ZFIN:ZDB-GENO-100528-8	Zfish	PMID:26637167
Biological Process	GO:0043488	regulation of mRNA stability	Fmr1	IMP		Mouse	MGI:MGI:3710908\|PMID:17417632
Biological Process	GO:0098908	regulation of neuronal action potential	FMR1	IDA		Human	PMID:25561520
Biological Process	GO:0098908	regulation of neuronal action potential	Fmr1	IMP		Rat	PMID:27465362\|RGD:38548926
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Fmr1	IMP		Mouse	MGI:MGI:3834811\|PMID:18614030
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Fmr1	IMP		Mouse	PMID:12032354
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Fmr1	IDA		Mouse	PMID:12032354
Biological Process	GO:0099577	regulation of translation at presynapse, modulating synaptic transmission	Fmr1	IDA		Rat	PMID:24709664\|RGD:11059581
Biological Process	GO:0099577	regulation of translation at presynapse, modulating synaptic transmission	Fmr1	IMP		Rat	PMID:24709664\|RGD:11059581
Biological Process	GO:0014823	response to activity	Fmr1	IEP		Rat	PMID:11001622\|RGD:11667957
Biological Process	GO:0042220	response to cocaine	Fmr1	IEP		Rat	PMID:24810662\|RGD:11667955
Biological Process	GO:0051602	response to electrical stimulus	Fmr1	IEP		Rat	PMID:10686356\|RGD:11566033
Biological Process	GO:0034698	response to gonadotropin	Fmr1	IEP		Rat	PMID:23401597\|RGD:11566032
Biological Process	GO:0070555	response to interleukin-1	Fmr1	IEP		Rat	PMID:10587350\|RGD:11566034
Biological Process	GO:0097396	response to interleukin-17	Fmr1	IMP	MGI:MGI:1857169	Mouse	PMID:31853066
Biological Process	GO:0009416	response to light stimulus	Fmr1	IEP		Rat	PMID:15564573\|RGD:1601175
Biological Process	GO:0035176	social behavior	Fmr1	IMP	MGI:MGI:1857169	Mouse	PMID:31853066
Biological Process	GO:0035176	social behavior	Fmr1	IMP	MGI:MGI:2677631	Mouse	PMID:31853066
Biological Process	GO:0035176	social behavior	Fmr1	IMP	MGI:MGI:4949738	Mouse	PMID:31853066
Biological Process	GO:0034063	stress granule assembly	FMR1	IDA		Human	PMID:12417522
Biological Process	GO:0019226	transmission of nerve impulse	Fmr1	IMP	MGI:MGI:3808885	Mouse	PMID:29901787

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.