Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CHURC1-FNTB,FNTB
  • Mouse genes Fntb
  • Rat genes Fntb
  • Zfish genes fntb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fntb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004311	farnesyltranstransferase activity	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Molecular Function	GO:0042277	peptide binding	Fntb	IDA		Rat	PMID:9705207|RGD:2302975
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:11687658
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:12036349
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:12825937
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:15170324
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:15248757
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:15451670
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:A5PL33-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:O43711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P21549	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:P49354	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:Q8N4L8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:Q8N5M1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:Q9BWW8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:Q9H0W8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FNTB	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:10377218|RGD:8553653
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:10673434|RGD:11041072
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:12657282|RGD:8554767
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:12657283|RGD:8554769
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:12657284|RGD:8554772
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:12667062|RGD:8554159
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:12699757|RGD:8554635
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:15170324|RGD:8553865
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:15451670|RGD:8553417
Molecular Function	GO:0005515	protein binding	Fntb	IPI	UniProtKB:Q04631	Rat	PMID:9065406|RGD:13432295
Molecular Function	GO:0004660	protein farnesyltransferase activity	FNTB	IDA		Human	PMID:19228685
Molecular Function	GO:0004660	protein farnesyltransferase activity	FNTB	IDA		Human	PMID:16893176
Molecular Function	GO:0004660	protein farnesyltransferase activity	Fntb	IDA		Rat	PMID:8089111|RGD:2302973
Molecular Function	GO:0004660	protein farnesyltransferase activity	Fntb	IDA		Rat	PMID:1855253|RGD:728425
Molecular Function	GO:0008270	zinc ion binding	FNTB	IDA		Human	PMID:16893176
Cellular Component	GO:0005875	microtubule associated complex	FNTB	IDA		Human	PMID:19228685
Cellular Component	GO:0005965	protein farnesyltransferase complex	FNTB	IDA		Human	PMID:16893176
Biological Process	GO:0003231	cardiac ventricle development	fntb	IMP	ZFIN:ZDB-MRPHLNO-150318-1	Zfish	PMID:25517466
Biological Process	GO:0008283	cell population proliferation	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Biological Process	GO:0048144	fibroblast proliferation	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Biological Process	GO:0045787	positive regulation of cell cycle	Fntb	IMP		Rat	PMID:10544242|RGD:2302976
Biological Process	GO:0008284	positive regulation of cell population proliferation	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Biological Process	GO:0008284	positive regulation of cell population proliferation	Fntb	IMP		Rat	PMID:10544242|RGD:2302976
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621
Biological Process	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process	Fntb	IMP		Rat	PMID:9153192|RGD:2302974
Biological Process	GO:0018343	protein farnesylation	FNTB	IDA		Human	PMID:16893176
Biological Process	GO:0018343	protein farnesylation	FNTB	IDA		Human	PMID:19228685
Biological Process	GO:0048145	regulation of fibroblast proliferation	Fntb	IMP		Mouse	PMID:23686339
Biological Process	GO:0034097	response to cytokine	Fntb	IMP		Rat	PMID:9153192|RGD:2302974
Biological Process	GO:0010035	response to inorganic substance	Fntb	IMP		Rat	PMID:18957540|RGD:2302981
Biological Process	GO:0014070	response to organic cyclic compound	Fntb	IMP		Rat	PMID:16257390|RGD:2302979
Biological Process	GO:0042060	wound healing	Fntb	IMP	MGI:MGI:3581448	Mouse	PMID:15837621

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern