Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOLR2,FOLR3
  • Mouse genes Folr2
  • Rat genes Folr2
  • Zfish genes folr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Folr2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005542	folic acid binding	FOLR2	IDA		Human	PMID:19116913
Molecular Function	GO:0005542	folic acid binding	FOLR2	IDA		Human	PMID:25015955
Molecular Function	GO:0005542	folic acid binding	FOLR2	IDA		Human	PMID:4066659
Molecular Function	GO:0061714	folic acid receptor activity	FOLR2	IDA		Human	PMID:4066659
Molecular Function	GO:0005515	protein binding	FOLR3	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOLR3	IPI	UniProtKB:X5D778	Human	PMID:32296183
Cellular Component	GO:0009986	cell surface	FOLR2	IDA		Human	PMID:25015955
Cellular Component	GO:0009897	external side of plasma membrane	FOLR2	IDA		Human	PMID:4066659
Biological Process	GO:0015884	folic acid transport	FOLR2	IDA		Human	PMID:4066659
Biological Process	GO:0008284	positive regulation of cell population proliferation	FOLR2	IMP		Human	PMID:19116913
Biological Process	GO:0010628	positive regulation of gene expression	Folr2	HMP		Rat	PMID:33633725|RGD:151665761

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern