Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOSL2
  • Mouse genes Fosl2
  • Rat genes Fosl2
  • Zfish genes fosl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fosl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Fosl2	IDA		Mouse	PMID:25547114
Molecular Function	GO:0003677	DNA binding	Fosl2	IDA		Rat	PMID:12358739|RGD:628397
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOSL2	IDA		Human	PMID:13679379
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Fosl2	IMP		Rat	PMID:10830307|RGD:1626699
Molecular Function	GO:0003690	double-stranded DNA binding	Fosl2	IDA		Rat	PMID:10830307|RGD:1626699
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17275	Human	PMID:19321746
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P05412	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P15336	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17275	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17535	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17544	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P35638	Human	PMID:20102225
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P35638-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q02930-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q13077	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q53SE7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q96EY1-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9HD26	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9P127	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P05412	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17275	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17535	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P35638	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q02930-3	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q13077	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P05412	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P15336	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17275	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17535	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9BYV9	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q13643	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9HD26	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P05412	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P15336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P17275	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P35638	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P62487	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q15438	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q5T3J3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q68G74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FOSL2	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOSL2	IDA		Human	PMID:13679379
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Fosl2	IDA		Mouse	PMID:19289495
Molecular Function	GO:0043565	sequence-specific DNA binding	Fosl2	IDA		Rat	PMID:10830307|RGD:1626699
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Fosl2	IDA		Rat	PMID:21367864|RGD:7247438
Cellular Component	GO:0005654	nucleoplasm	FOSL2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Fosl2	IDA		Mouse	PMID:25547114
Cellular Component	GO:0005634	nucleus	Fosl2	IDA		Rat	PMID:10830307|RGD:1626699
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	FOSL2	IPI		Human	PMID:20102225
Biological Process	GO:0007568	aging	Fosl2	IEP		Rat	PMID:11389931|RGD:2293789
Biological Process	GO:0007623	circadian rhythm	Fosl2	IEP		Rat	PMID:10987819|RGD:2293795
Biological Process	GO:0007623	circadian rhythm	Fosl2	IEP		Rat	PMID:21367864|RGD:7247438
Biological Process	GO:0001661	conditioned taste aversion	Fosl2	IEP		Rat	PMID:18374904|RGD:2293760
Biological Process	GO:0007565	female pregnancy	Fosl2	IEP		Rat	PMID:12080023|RGD:2293785
Biological Process	GO:0003334	keratinocyte development	Fosl2	IMP		Mouse	PMID:25547114
Biological Process	GO:0009648	photoperiodism	Fosl2	IEP		Rat	PMID:16962714|RGD:2293767
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fosl2	IDA		Mouse	MGI:MGI:5438169|PMID:22585681
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fosl2	IDA		Rat	PMID:11340164|RGD:628507
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Fosl2	IDA		Mouse	PMID:7936655
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOSL2	IDA		Human	PMID:13679379
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Fosl2	IDA		Mouse	PMID:25547114
Biological Process	GO:2000690	regulation of cardiac muscle cell myoblast differentiation	fosl2	IMP	ZFIN:ZDB-GENO-160531-4	Zfish	PMID:26732840
Biological Process	GO:2000690	regulation of cardiac muscle cell myoblast differentiation	fosl2	IMP	ZFIN:ZDB-GENO-160531-5	Zfish	PMID:26732840
Biological Process	GO:0051591	response to cAMP	Fosl2	IEP		Rat	PMID:18280640|RGD:2293762
Biological Process	GO:0009409	response to cold	Fosl2	IEP		Rat	PMID:16169632|RGD:2293774
Biological Process	GO:0034097	response to cytokine	Fosl2	IEP		Rat	PMID:18280640|RGD:2293762
Biological Process	GO:0032355	response to estradiol	Fosl2	IMP		Rat	PMID:12021174|RGD:625744
Biological Process	GO:0001666	response to hypoxia	Fosl2	IMP		Rat	PMID:15892448|RGD:2293775
Biological Process	GO:0035902	response to immobilization stress	Fosl2	IEP		Rat	PMID:17936518|RGD:2293763
Biological Process	GO:0009416	response to light stimulus	Fosl2	IEP		Rat	PMID:11146118|RGD:2293791
Biological Process	GO:0009612	response to mechanical stimulus	Fosl2	IEP		Rat	PMID:16373449|RGD:2293772
Biological Process	GO:0014070	response to organic cyclic compound	Fosl2	IEP		Rat	PMID:11113530|RGD:2293792
Biological Process	GO:0043434	response to peptide hormone	Fosl2	IEP		Rat	PMID:10934195|RGD:2293796
Biological Process	GO:0032570	response to progesterone	Fosl2	IEP		Rat	PMID:12080023|RGD:2293785
Biological Process	GO:0009636	response to toxic substance	Fosl2	IEP		Rat	PMID:11295234|RGD:2293790
Biological Process	GO:0030431	sleep	Fosl2	IEP		Rat	PMID:16690212|RGD:2293769
Biological Process	GO:0006366	transcription by RNA polymerase II	Fosl2	IMP		Rat	PMID:10830307|RGD:1626699

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern