Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxd3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FOXD3
- Mouse genes Foxd3
- Rat genes Foxd3
- Zfish genes foxd3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Foxd3	IDA		Rat	PMID:7683413\|RGD:632667
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxd3	IDA		Mouse	MGI:MGI:82951\|PMID:8798505
Molecular Function	GO:0003700	DNA-binding transcription factor activity	foxd3	IDA		Zfish	PMID:16386728
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	FOXD3	IDA		Human	PMID:22306510
Molecular Function	GO:0003690	double-stranded DNA binding	Foxd3	IMP		Rat	PMID:7683413\|RGD:632667
Molecular Function	GO:0005515	protein binding	FOXD3	IPI	UniProtKB:Q01860	Human	PMID:11891324
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXD3	IDA		Human	PMID:22306510
Molecular Function	GO:0043565	sequence-specific DNA binding	foxd3	IDA		Zfish	PMID:18068699
Molecular Function	GO:0043565	sequence-specific DNA binding	foxd3	IDA		Zfish	PMID:16386728
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXD3	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxd3	IDA		Mouse	PMID:7958446
Cellular Component	GO:0000785	chromatin	FOXD3	IDA		Human	PMID:22306510
Biological Process	GO:0051216	cartilage development	foxd3	IMP	ZFIN:ZDB-MRPHLNO-050818-7	Zfish	PMID:16364284
Biological Process	GO:0060351	cartilage development involved in endochondral bone morphogenesis	foxd3	IMP	ZFIN:ZDB-GENO-100624-1	Zfish	PMID:21931719
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Foxd3	IEP		Mouse	PMID:20439489
Biological Process	GO:0001892	embryonic placenta development	Foxd3	IMP	MGI:MGI:2388719	Mouse	PMID:16039639
Biological Process	GO:0048484	enteric nervous system development	foxd3	IMP	ZFIN:ZDB-MRPHLNO-050818-7	Zfish	PMID:16364284
Biological Process	GO:0048484	enteric nervous system development	foxd3	IMP	ZFIN:ZDB-GENO-060519-2	Zfish	PMID:16499899
Biological Process	GO:0001701	in utero embryonic development	Foxd3	IDA		Mouse	MGI:MGI:2388404\|PMID:12381664
Biological Process	GO:0050935	iridophore differentiation	foxd3	IMP	ZFIN:ZDB-MRPHLNO-050818-7	Zfish	PMID:16364284
Biological Process	GO:0048937	lateral line nerve glial cell development	foxd3	IMP	ZFIN:ZDB-MRPHLNO-050818-7	Zfish	PMID:16364284
Biological Process	GO:0030318	melanocyte differentiation	foxd3	IGI	ZFIN:ZDB-GENO-071220-28,ZFIN:ZDB-MRPHLNO-060522-7	Zfish	PMID:18068699
Biological Process	GO:0030318	melanocyte differentiation	foxd3	IGI	ZFIN:ZDB-GENO-080804-2	Zfish	PMID:18068699
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	foxd3	IDA		Zfish	PMID:19527705
Biological Process	GO:0010629	negative regulation of gene expression	foxd3	IMP	ZFIN:ZDB-GENO-100511-4	Zfish	PMID:19527705
Biological Process	GO:0010629	negative regulation of gene expression	foxd3	IGI	ZFIN:ZDB-GENE-990910-11	Zfish	PMID:19527705
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FOXD3	IDA		Human	PMID:22306510
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxd3	IDA		Mouse	MGI:MGI:82951\|PMID:8798505
Biological Process	GO:0014032	neural crest cell development	foxd3	IGI	ZFIN:ZDB-GENO-120530-2	Zfish	PMID:21963426
Biological Process	GO:0014032	neural crest cell development	foxd3	IGI	ZFIN:ZDB-GENO-110803-2	Zfish	PMID:19955371
Biological Process	GO:0014032	neural crest cell development	foxd3	IGI	ZFIN:ZDB-GENO-120530-3	Zfish	PMID:21963426
Biological Process	GO:0014032	neural crest cell development	foxd3	IMP	ZFIN:ZDB-GENO-980202-246	Zfish	PMID:17013879
Biological Process	GO:0014032	neural crest cell development	foxd3	IGI	ZFIN:ZDB-GENO-120220-11	Zfish	PMID:19439494
Biological Process	GO:0014032	neural crest cell development	foxd3	IMP	ZFIN:ZDB-GENO-130314-3	Zfish	PMID:23228892
Biological Process	GO:0001755	neural crest cell migration	foxd3	IMP	ZFIN:ZDB-GENO-060519-2	Zfish	PMID:16499899
Biological Process	GO:0007422	peripheral nervous system development	foxd3	IMP	ZFIN:ZDB-MRPHLNO-050818-7	Zfish	PMID:16364284
Biological Process	GO:0050931	pigment cell differentiation	foxd3	IGI	ZFIN:ZDB-GENO-120220-11	Zfish	PMID:19439494
Biological Process	GO:0050931	pigment cell differentiation	foxd3	IMP	ZFIN:ZDB-GENO-060519-2	Zfish	PMID:16499899
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXD3	IDA		Human	PMID:11891324
Biological Process	GO:0097066	response to thyroid hormone	foxd3	IDA		Zfish	PMID:27832141
Biological Process	GO:0048485	sympathetic nervous system development	foxd3	IMP	ZFIN:ZDB-GENO-060519-2	Zfish	PMID:16499899
Biological Process	GO:0006366	transcription by RNA polymerase II	foxd3	IDA		Zfish	PMID:16386728
Biological Process	GO:0001829	trophectodermal cell differentiation	Foxd3	IMP	MGI:MGI:2388719	Mouse	PMID:16039639

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.