Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXE3
  • Mouse genes Foxe3
  • Rat genes Foxe3
  • Zfish genes foxe3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxe3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	FOXE3	IDA		Human	PMID:25504734
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXE3	IDA		Human	PMID:10652278
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXE3	IDA		Human	PMID:25504734
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxe3	IDA		Mouse	MGI:MGI:2179783|PMID:11980846
Cellular Component	GO:0005634	nucleus	FOXE3	IDA		Human	PMID:25504734
Cellular Component	GO:0005634	nucleus	Foxe3	IDA		Mouse	MGI:MGI:3703484|PMID:17064680
Cellular Component	GO:0005667	transcription regulator complex	FOXE3	IDA		Human	PMID:10652278
Biological Process	GO:0035904	aorta development	foxe3	IGI	ZFIN:ZDB-MRPHLNO-080801-6,ZFIN:ZDB-MRPHLNO-160909-1	Zfish	PMID:26854927
Biological Process	GO:0035904	aorta development	foxe3	IMP	ZFIN:ZDB-MRPHLNO-080801-6	Zfish	PMID:26854927
Biological Process	GO:0043010	camera-type eye development	Foxe3	IMP	MGI:MGI:2387330	Mouse	PMID:11309658
Biological Process	GO:0048468	cell development	Foxe3	IMP	MGI:MGI:3604211	Mouse	PMID:16199865
Biological Process	GO:0061073	ciliary body morphogenesis	Foxe3	IMP		Mouse	MGI:MGI:3703484|PMID:17064680
Biological Process	GO:0061303	cornea development in camera-type eye	Foxe3	IMP		Mouse	MGI:MGI:3703484|PMID:17064680
Biological Process	GO:0050673	epithelial cell proliferation	Foxe3	IMP	MGI:MGI:3604211	Mouse	PMID:16199865
Biological Process	GO:0001654	eye development	FOXE3	IMP		Human	PMID:27218149
Biological Process	GO:0001654	eye development	Foxe3	IMP	MGI:MGI:1856851	Mouse	PMID:10652278
Biological Process	GO:0001654	eye development	foxe3	IMP	ZFIN:ZDB-MRPHLNO-061215-1	Zfish	PMID:16963235
Biological Process	GO:0061072	iris morphogenesis	Foxe3	IMP		Mouse	MGI:MGI:3703484|PMID:17064680
Biological Process	GO:0002088	lens development in camera-type eye	FOXE3	IMP		Human	PMID:27218149
Biological Process	GO:0002088	lens development in camera-type eye	Foxe3	IMP		Mouse	MGI:MGI:3703484|PMID:17064680
Biological Process	GO:0002088	lens development in camera-type eye	foxe3	IMP	ZFIN:ZDB-MRPHLNO-061215-1	Zfish	PMID:16963235
Biological Process	GO:0002089	lens morphogenesis in camera-type eye	foxe3	IMP	ZFIN:ZDB-MRPHLNO-080801-6	Zfish	PMID:18327772
Biological Process	GO:0042789	mRNA transcription by RNA polymerase II	FOXE3	IDA		Human	PMID:27218149
Biological Process	GO:0043066	negative regulation of apoptotic process	FOXE3	IMP		Human	PMID:22527307
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	Foxe3	IMP		Mouse	MGI:MGI:1861492|PMID:10890982
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	Foxe3	IMP		Mouse	MGI:MGI:3603877|PMID:16199865
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	Foxe3	IMP		Mouse	MGI:MGI:1352262|PMID:10652278
Biological Process	GO:1902747	negative regulation of lens fiber cell differentiation	foxe3	IMP	ZFIN:ZDB-GENO-181022-1	Zfish	PMID:29713869
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Foxe3	IMP	MGI:MGI:3604211	Mouse	PMID:16199865
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	FOXE3	IMP		Human	PMID:22527307
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	Foxe3	IMP		Mouse	MGI:MGI:3603877|PMID:16199865
Biological Process	GO:2001111	positive regulation of lens epithelial cell proliferation	Foxe3	IMP		Mouse	MGI:MGI:1352262|PMID:10652278
Biological Process	GO:0051726	regulation of cell cycle	FOXE3	IMP		Human	PMID:22527307
Biological Process	GO:0002930	trabecular meshwork development	Foxe3	IMP		Mouse	MGI:MGI:3703484|PMID:17064680
Biological Process	GO:0006366	transcription by RNA polymerase II	FOXE3	IDA		Human	PMID:10652278

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern