Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXF2
  • Mouse genes Foxf2
  • Rat genes
  • Zfish genes foxf2a,foxf2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	FOXF2	IDA		Human	PMID:7957066
Molecular Function	GO:0003677	DNA binding	Foxf2	IDA		Mouse	PMID:9676429
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXF2	IDA		Human	PMID:8626802
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXF2	IMP		Human	PMID:8626802
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXF2	IDA		Human	PMID:9722567
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxf2	IDA		Mouse	PMID:9676429
Molecular Function	GO:0140296	general transcription initiation factor binding	FOXF2	IPI	UniProtKB:P20226	Human	PMID:9722567
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXF2	IDA		Human	PMID:8626802
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXF2	IDA		Human	PMID:7957066
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXF2	IDA		Human	PMID:8626802
Molecular Function	GO:0001093	TFIIB-class transcription factor binding	FOXF2	IPI	UniProtKB:Q00403	Human	PMID:9722567
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	FOXF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	FOXF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FOXF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FOXF2	IDA		Human	PMID:29374064
Cellular Component	GO:0005634	nucleus	FOXF2	IDA		Human	PMID:9722567
Cellular Component	GO:0005634	nucleus	FOXF2	IDA		Human	PMID:9799607
Cellular Component	GO:0005634	nucleus	Foxf2	IDA		Mouse	PMID:17261592
Cellular Component	GO:0005667	transcription regulator complex	FOXF2	IDA		Human	PMID:9722567
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	Foxf2	IMP		Mouse	MGI:MGI:5297296|PMID:22022403
Biological Process	GO:0048566	embryonic digestive tract development	Foxf2	IGI	MGI:MGI:1347470	Mouse	PMID:16439479
Biological Process	GO:0042249	establishment of planar polarity of embryonic epithelium	Foxf2	IGI	MGI:MGI:1347470	Mouse	PMID:16439479
Biological Process	GO:0042249	establishment of planar polarity of embryonic epithelium	Foxf2	IMP	MGI:MGI:2667134	Mouse	PMID:16439479
Biological Process	GO:0030198	extracellular matrix organization	Foxf2	IGI	MGI:MGI:1347470	Mouse	PMID:16439479
Biological Process	GO:0030198	extracellular matrix organization	Foxf2	IMP	MGI:MGI:2667134	Mouse	PMID:16439479
Biological Process	GO:0048806	genitalia development	FOXF2	IMP		Human	PMID:19276632
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Foxf2	IDA		Mouse	PMID:9676429
Biological Process	GO:1904238	pericyte cell differentiation	foxf2b	IMP	ZFIN:ZDB-GENO-160809-1	Zfish	PMID:27068588
Biological Process	GO:1904238	pericyte cell differentiation	foxf2b	IMP	ZFIN:ZDB-GENO-160809-2	Zfish	PMID:27068588
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXF2	IDA		Human	PMID:8626802
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXF2	IDA		Human	PMID:8626802
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXF2	IMP		Human	PMID:8626802
Biological Process	GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	FOXF2	IDA		Human	PMID:29374064
Biological Process	GO:1902914	regulation of protein polyubiquitination	FOXF2	IDA		Human	PMID:29374064
Biological Process	GO:0060021	roof of mouth development	FOXF2	IMP		Human	PMID:19276632
Biological Process	GO:0097084	vascular associated smooth muscle cell development	foxf2b	IMP	ZFIN:ZDB-GENO-160809-2	Zfish	PMID:27068588
Biological Process	GO:0097084	vascular associated smooth muscle cell development	foxf2b	IMP	ZFIN:ZDB-GENO-160809-1	Zfish	PMID:27068588

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern