About   Help   FAQ
Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxh1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxh1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0043425bHLH transcription factor bindingFOXH1IPIUniProtKB:P15923HumanPMID:21828274
Molecular FunctionGO:0043425bHLH transcription factor bindingFOXH1IPIUniProtKB:Q99081HumanPMID:21828274
Molecular FunctionGO:0070410co-SMAD bindingFOXH1IMPHumanPMID:16120611
Molecular FunctionGO:0003677DNA bindingFOXH1IDAHumanPMID:9389648
Molecular FunctionGO:0003677DNA bindingFoxh1IDAMousePMID:9702197
Molecular FunctionGO:0003677DNA bindingFoxh1IDAMousePMID:15363409
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificFoxh1IDAMousePMID:18331719
Molecular FunctionGO:0003700DNA-binding transcription factor activityFOXH1IDAHumanPMID:17438144
Molecular FunctionGO:0003700DNA-binding transcription factor activityFoxh1IDAMousePMID:9702197
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:17306248
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificfoxh1IDAZfishPMID:17306248
Molecular FunctionGO:0000981DNA-binding transcription factor activity, RNA polymerase II-specificfoxh1IGIZFIN:ZDB-MRPHLNO-070529-5ZfishPMID:17306248
Molecular FunctionGO:0140297DNA-binding transcription factor bindingFOXH1IPIUniProtKB:Q7T103HumanPMID:18922797
Molecular FunctionGO:0001227DNA-binding transcription repressor activity, RNA polymerase II-specificfoxh1IDAZfishPMID:26618989
Molecular FunctionGO:0050681nuclear androgen receptor bindingFOXH1IPIUniProtKB:P10275HumanPMID:16120611
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P10275HumanPMID:16120611
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P16333HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P15923HumanPMID:21828274
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P84022HumanPMID:21828274
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q99081HumanPMID:21828274
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:A1KXE4-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:A8MQ03HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:A8MTQ0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O15496HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O43186HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O43711HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O60548HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O75864HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:O95416HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P05813HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P0C7T5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P19801HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P35548HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P40199HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P49639HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P84022HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:P86480HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q03989HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q14774HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q14847-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q15038HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q15796HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q15915HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q3LHN2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q3LI70HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q3SY46HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q3SYF9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q53HC5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q5BKX5-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q5SWW7HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q5T6F2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q6NVU6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q6ZRY4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q86UY5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q86WV8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q8IUC1HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q8IUC3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q8N1L9HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q8TBY0HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q8TDS5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q92734HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q96F45HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q96K80HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q96M29HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q96PV4HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9BSH5HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9BYR6HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9BYR8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9H5F2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9UGK8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9ULV5-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9Y5J3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9Y5V3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q9Y6H3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingFOXH1IPIUniProtKB:Q15796HumanPMID:9702198
Molecular FunctionGO:0005515protein bindingFoxh1IPIPR:P42582MousePMID:15363409
Molecular FunctionGO:0005515protein bindingFoxh1IPIPR:Q9D6N5MousePMID:12471260
Molecular FunctionGO:0005515protein bindingFoxh1IPIPR:Q02591MousePMID:17568773
Molecular FunctionGO:0005515protein bindingFoxh1IPIPR:Q62432MousePMID:9702197
Molecular FunctionGO:0019904protein domain specific bindingFOXH1IPIUniProtKB:Q15796HumanPMID:9702198
Molecular FunctionGO:0070412R-SMAD bindingFOXH1IMPHumanPMID:16120611
Molecular FunctionGO:0070412R-SMAD bindingFOXH1IPIUniProtKB:Q15796HumanPMID:9389648
Molecular FunctionGO:0070412R-SMAD bindingFOXH1IPIUniProtKB:Q15796HumanPMID:9702198
Molecular FunctionGO:0070412R-SMAD bindingFoxh1IDAMouseMGI:MGI:1321467|PMID:9858566
Molecular FunctionGO:0000977RNA polymerase II transcription regulatory region sequence-specific DNA bindingfoxh1IDAZfishPMID:26618989
Molecular FunctionGO:0043565sequence-specific DNA bindingFOXH1IDAHumanPMID:9702198
Molecular FunctionGO:0043565sequence-specific DNA bindingFoxh1IDAMousePMID:17568773
Molecular FunctionGO:0043565sequence-specific DNA bindingfoxh1IDAZfishPMID:26618989
Molecular FunctionGO:0043565sequence-specific DNA bindingfoxh1IMPZFIN:ZDB-GENO-111207-3ZfishPMID:21637786
Molecular FunctionGO:0046332SMAD bindingFOXH1IPIUniProtKB:P84022HumanPMID:21828274
Molecular FunctionGO:0046332SMAD bindingFoxh1IPIUniProtKB:Q62432MouseMGI:MGI:1276222|PMID:9702197
Molecular FunctionGO:0046332SMAD bindingfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Molecular FunctionGO:0000976transcription cis-regulatory region bindingFoxh1IDAMouseMGI:MGI:1321467|PMID:9858566
Molecular FunctionGO:0000976transcription cis-regulatory region bindingfoxh1IDAZfishPMID:26618989
Cellular ComponentGO:0032444activin responsive factor complexFOXH1IDAHumanPMID:9389648
Cellular ComponentGO:0032444activin responsive factor complexFoxh1IDAMouseMGI:MGI:1328655|PMID:10349617
Cellular ComponentGO:0032444activin responsive factor complexFoxh1IDAMouseMGI:MGI:1321467|PMID:9858566
Cellular ComponentGO:0000785chromatinFOXH1IDAHumanPMID:21828274
Cellular ComponentGO:0000785chromatinfoxh1IDAZfishPMID:26618989
Cellular ComponentGO:0005634nucleusFOXH1IDAHumanPMID:16120611
Cellular ComponentGO:0005634nucleusFoxh1IDAMousePMID:9702197
Cellular ComponentGO:0005667transcription regulator complexFOXH1IDAHumanPMID:17438144
Cellular ComponentGO:0005667transcription regulator complexFoxh1IDAMousePMID:17568773
Cellular ComponentGO:0005667transcription regulator complexFoxh1IDAMousePMID:9702197
Biological ProcessGO:0009952anterior/posterior pattern specificationFoxh1IMPMGI:MGI:2387775MousePMID:11358868
Biological ProcessGO:0035909aorta morphogenesisFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0048318axial mesoderm developmentFoxh1IMPMGI:MGI:2179442MousePMID:11358869
Biological ProcessGO:0048319axial mesoderm morphogenesisfoxh1IMPZFIN:ZDB-GENO-111207-3ZfishPMID:21637786
Biological ProcessGO:0048327axial mesodermal cell fate specificationfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:0001568blood vessel developmentfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:17306248
Biological ProcessGO:0048854brain morphogenesisfoxh1IMPZFIN:ZDB-GENO-980202-260ZfishPMID:9007238
Biological ProcessGO:0003215cardiac right ventricle morphogenesisFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0042074cell migration involved in gastrulationfoxh1IMPZFIN:ZDB-MRPHLNO-080110-2ZfishPMID:17719025
Biological ProcessGO:0042074cell migration involved in gastrulationfoxh1IMPZFIN:ZDB-MRPHLNO-080110-1ZfishPMID:17719025
Biological ProcessGO:0071345cellular response to cytokine stimulusFOXH1IMPHumanPMID:14671321
Biological ProcessGO:0007368determination of left/right symmetryFoxh1IMPMGI:MGI:2387775MousePMID:12642485
Biological ProcessGO:0007368determination of left/right symmetryfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:10903181
Biological ProcessGO:0007368determination of left/right symmetryfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:9334285
Biological ProcessGO:0009953dorsal/ventral pattern formationfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:10996071
Biological ProcessGO:0035054embryonic heart tube anterior/posterior pattern specificationFoxh1IMPMGI:MGI:2179442MousePMID:15363409
Biological ProcessGO:0060971embryonic heart tube left/right pattern formationfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:0003143embryonic heart tube morphogenesisfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:9334285
Biological ProcessGO:0001706endoderm formationfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:10996071
Biological ProcessGO:0033504floor plate developmentfoxh1IMPZFIN:ZDB-GENO-980202-260ZfishPMID:9007234
Biological ProcessGO:0021508floor plate formationfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:10694427
Biological ProcessGO:0001947heart loopingFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0001947heart loopingfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:9334285
Biological ProcessGO:0070365hepatocyte differentiationFoxh1IEPRatPMID:22715131|RGD:155791677
Biological ProcessGO:0021854hypothalamus developmentfoxh1IMPZFIN:ZDB-GENO-980202-260ZfishPMID:9007238
Biological ProcessGO:0046619lens placode formation involved in camera-type eye formationfoxh1IMPZFIN:ZDB-GENO-980202-260ZfishPMID:9007234
Biological ProcessGO:0048382mesendoderm developmentfoxh1IGIZFIN:ZDB-GENE-001228-1,ZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:0001707mesoderm formationfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:10996071
Biological ProcessGO:0060766negative regulation of androgen receptor signaling pathwayFOXH1IDAHumanPMID:16120611
Biological ProcessGO:0043433negative regulation of DNA-binding transcription factor activityFOXH1IDAHumanPMID:16120611
Biological ProcessGO:0033147negative regulation of intracellular estrogen receptor signaling pathwayFOXH1IDAHumanPMID:16120611
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIFoxh1IGIMGI:MGI:95841MousePMID:17568773
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIfoxh1IDAZfishPMID:26618989
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:17306248
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IIfoxh1IDAZfishPMID:17306248
Biological ProcessGO:0030903notochord developmentfoxh1IMPZFIN:ZDB-GENO-980202-260ZfishPMID:9007234
Biological ProcessGO:0014028notochord formationfoxh1IMPZFIN:ZDB-GENO-111207-3ZfishPMID:21637786
Biological ProcessGO:0014028notochord formationfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:0003151outflow tract morphogenesisFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionFOXH1IDAHumanPMID:9389648
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionFOXH1IDAHumanPMID:9702198
Biological ProcessGO:0045893positive regulation of DNA-templated transcriptionFoxh1IDAMouseMGI:MGI:1328655|PMID:10349617
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIFOXH1IMPHumanPMID:14671321
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIFOXH1IDAHumanPMID:9702198
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIFoxh1IDAMouseMGI:MGI:1321467|PMID:9858566
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIFoxh1IDAMouseMGI:MGI:1328655|PMID:10349617
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IIFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0021501prechordal plate formationfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:2000223regulation of BMP signaling pathway involved in heart joggingfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:9334285
Biological ProcessGO:2000223regulation of BMP signaling pathway involved in heart joggingfoxh1IMPZFIN:ZDB-GENO-141202-2ZfishPMID:23358434
Biological ProcessGO:0010468regulation of gene expressionfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:10996071
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIFoxh1IDAMousePMID:9702197
Biological ProcessGO:0006357regulation of transcription by RNA polymerase IIfoxh1IGIZFIN:ZDB-MRPHLNO-070529-5ZfishPMID:17306248
Biological ProcessGO:0003139secondary heart field specificationFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0032525somite rostral/caudal axis specificationfoxh1IMPZFIN:ZDB-GENO-111207-2ZfishPMID:21637786
Biological ProcessGO:0010159specification of animal organ positionfoxh1IMPZFIN:ZDB-GENO-980202-1029ZfishPMID:10903181
Biological ProcessGO:0060063Spemann organizer formation at the embryonic shieldfoxh1IMPZFIN:ZDB-GENO-070529-4ZfishPMID:10996071
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayFoxh1IDAMouseMGI:MGI:1328655|PMID:10349617
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayFoxh1IMPMouseMGI:MGI:1321467|PMID:9858566
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayFoxh1IDAMouseMGI:MGI:3055632|PMID:15363409
Biological ProcessGO:0003222ventricular trabecula myocardium morphogenesisFoxh1IMPMouseMGI:MGI:3055632|PMID:15363409

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory