Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXN1
  • Mouse genes Foxn1
  • Rat genes Foxn1
  • Zfish genes foxn1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Foxn1	IDA		Mouse	MGI:MGI:87160|PMID:9108066
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Foxn1	IMP		Mouse	MGI:MGI:87160|PMID:9108066
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:O60336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:O75865-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:P32320	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q08117-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q68G74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q9BXA7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q9H0A9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q9NQL9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXN1	IPI	UniProtKB:Q9UJX2	Human	PMID:32296183
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxn1	IDA		Mouse	MGI:MGI:87160|PMID:9108066
Molecular Function	GO:0000976	transcription cis-regulatory region binding	foxn1	IPI	ZFIN:ZDB-GENE-020419-24	Zfish	PMID:23213226
Biological Process	GO:0048514	blood vessel morphogenesis	Foxn1	IMP		Mouse	MGI:MGI:4413531|PMID:19853842
Biological Process	GO:0008544	epidermis development	Foxn1	IMP	MGI:MGI:5297717	Mouse	PMID:22072979
Biological Process	GO:0001942	hair follicle development	Foxn1	IMP	MGI:MGI:1856108	Mouse	PMID:21191399
Biological Process	GO:0030097	hemopoiesis	Foxn1	IMP		Mouse	MGI:MGI:5554515|PMID:24184560
Biological Process	GO:0030216	keratinocyte differentiation	Foxn1	IDA		Mouse	PMID:11841548
Biological Process	GO:0030216	keratinocyte differentiation	Foxn1	IMP		Rat	PMID:8790387|RGD:1300512
Biological Process	GO:0002260	lymphocyte homeostasis	Foxn1	IMP	MGI:MGI:5297717	Mouse	PMID:22072979
Biological Process	GO:0097535	lymphoid lineage cell migration into thymus	Foxn1	IMP		Mouse	MGI:MGI:4413531|PMID:19853842
Biological Process	GO:0035878	nail development	Foxn1	IMP	MGI:MGI:1856108	Mouse	PMID:21191399
Biological Process	GO:0030858	positive regulation of epithelial cell differentiation	FOXN1	IDA		Human	PMID:24383669
Biological Process	GO:0051798	positive regulation of hair follicle development	Foxn1	IMP		Mouse	MGI:MGI:5437206|PMID:21109991
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxn1	IMP		Mouse	MGI:MGI:87160|PMID:9108066
Biological Process	GO:0010468	regulation of gene expression	Foxn1	IMP		Mouse	PMID:17683113
Biological Process	GO:1902232	regulation of positive thymic T cell selection	Foxn1	IMP		Mouse	MGI:MGI:5554515|PMID:24184560
Biological Process	GO:0033081	regulation of T cell differentiation in thymus	Foxn1	IMP	MGI:MGI:5297717	Mouse	PMID:22072979
Biological Process	GO:0043029	T cell homeostasis	Foxn1	IMP		Mouse	MGI:MGI:5554515|PMID:24184560
Biological Process	GO:0002360	T cell lineage commitment	Foxn1	IMP		Mouse	MGI:MGI:5554515|PMID:24184560
Biological Process	GO:0048538	thymus development	Foxn1	IMP	MGI:MGI:5297717	Mouse	PMID:22072979
Biological Process	GO:0048538	thymus development	Foxn1	IMP		Rat	PMID:8790387|RGD:1300512
Biological Process	GO:0048538	thymus development	foxn1	IMP	ZFIN:ZDB-MRPHLNO-101026-3	Zfish	PMID:19559469
Biological Process	GO:0048538	thymus development	foxn1	IMP	ZFIN:ZDB-MRPHLNO-101026-3	Zfish	PMID:23213226
Biological Process	GO:0097536	thymus epithelium morphogenesis	Foxn1	IMP		Mouse	MGI:MGI:5437206|PMID:21109991

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern