Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FOXP1
- Mouse genes Foxp1
- Rat genes Foxp1
- Zfish genes foxp1a,foxp1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Foxp1	IDA		Mouse	PMID:18347093
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	FOXP1	IDA		Human	PMID:28218735
Molecular Function	GO:0003677	DNA binding	Foxp1	IDA		Mouse	PMID:14701752
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxp1	IDA		Mouse	PMID:19797899
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxp1	IDA		Mouse	PMID:17428829
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Foxp1	IGI	MGI:MGI:1337080	Mouse	PMID:18347093
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Foxp1	IDA		Mouse	PMID:16819554
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Foxp1	IDA		Mouse	MGI:MGI:2137760\|PMID:11358962
Molecular Function	GO:0042802	identical protein binding	FOXP1	IPI	UniProtKB:Q9H334	Human	PMID:25609649
Molecular Function	GO:0042802	identical protein binding	FOXP1	IPI	UniProtKB:Q9H334	Human	PMID:25853299
Molecular Function	GO:0042802	identical protein binding	FOXP1	IPI	UniProtKB:Q9H334	Human	PMID:26647308
Molecular Function	GO:0042802	identical protein binding	Foxp1	IPI	PR:P58462	Mouse	PMID:14701752
Molecular Function	GO:0050681	nuclear androgen receptor binding	FOXP1	IDA		Human	PMID:18640093
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:Q9WU42	Human	PMID:18347093
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:P10275	Human	PMID:18640093
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:19907493
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:24893771
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:25027557
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:Q8IVH2	Human	PMID:25027557
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:Q8IVH2	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:25853299
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O15409	Human	PMID:26647308
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:O14965	Human	PMID:28218735
Molecular Function	GO:0005515	protein binding	FOXP1	IPI	UniProtKB:Q16650	Human	PMID:30250039
Molecular Function	GO:0005515	protein binding	Foxp1	IPI	PR:Q9DBY0	Mouse	PMID:14701752
Molecular Function	GO:0005515	protein binding	Foxp1	IPI	PR:P58463	Mouse	PMID:14701752
Molecular Function	GO:0043621	protein self-association	FOXP1	IMP		Human	PMID:26647308
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Foxp1	IMP		Mouse	MGI:MGI:3606794\|PMID:14701752
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXP1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxp1	IDA		Rat	PMID:21606195\|RGD:11561924
Molecular Function	GO:0001221	transcription coregulator binding	Foxp1	IPI	UniProtKB:O88712	Mouse	MGI:MGI:3606794\|PMID:14701752
Cellular Component	GO:0005737	cytoplasm	Foxp1	IDA		Rat	PMID:26842647\|RGD:11561903
Cellular Component	GO:0005634	nucleus	FOXP1	IDA		Human	PMID:25027557
Cellular Component	GO:0005634	nucleus	FOXP1	IDA		Human	PMID:26647308
Cellular Component	GO:0005634	nucleus	Foxp1	IDA		Mouse	PMID:16819554
Cellular Component	GO:0005634	nucleus	Foxp1	IDA		Mouse	PMID:23610558
Cellular Component	GO:0005634	nucleus	Foxp1	IDA		Mouse	PMID:19797899
Cellular Component	GO:0005634	nucleus	Foxp1	IDA		Rat	PMID:26842647\|RGD:11561903
Biological Process	GO:0055007	cardiac muscle cell differentiation	Foxp1	IMP	MGI:MGI:4829787	Mouse	PMID:20713518
Biological Process	GO:0055007	cardiac muscle cell differentiation	Foxp1	IMP	MGI:MGI:3056542	Mouse	PMID:15342473
Biological Process	GO:1904637	cellular response to ionomycin	Foxp1	IDA		Rat	PMID:21606195\|RGD:11561924
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Foxp1	IEP		Rat	PMID:26842647\|RGD:11561903
Biological Process	GO:0006974	DNA damage response	FOXP1	IMP		Human	PMID:30111844
Biological Process	GO:0009790	embryo development	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:16819554
Biological Process	GO:0009790	embryo development	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:0042118	endothelial cell activation	FOXP1	IMP		Human	PMID:24023716
Biological Process	GO:0030900	forebrain development	Foxp1	IEP		Rat	PMID:18561326\|RGD:11561932
Biological Process	GO:0007507	heart development	Foxp1	IMP	MGI:MGI:3056542	Mouse	PMID:15342473
Biological Process	GO:0033152	immunoglobulin V(D)J recombination	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:16819554
Biological Process	GO:0098582	innate vocalization behavior	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:26494785
Biological Process	GO:0030324	lung development	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:0061140	lung secretory cell differentiation	Foxp1	IGI	MGI:MGI:1921373	Mouse	PMID:22675208
Biological Process	GO:0042116	macrophage activation	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0042117	monocyte activation	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0008045	motor neuron axon guidance	Foxp1	IMP		Mouse	MGI:MGI:4849611\|PMID:20711475
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	FOXP1	IDA		Human	PMID:18640093
Biological Process	GO:0002903	negative regulation of B cell apoptotic process	FOXP1	IDA		Human	PMID:25267198
Biological Process	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development	Foxp1	IMP		Rat	PMID:26333362\|RGD:11561912
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP1	IDA		Human	PMID:20950788
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP1	IMP		Human	PMID:26647308
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Foxp1	IDA		Mouse	PMID:11358962
Biological Process	GO:0010629	negative regulation of gene expression	FOXP1	IDA		Human	PMID:30111844
Biological Process	GO:1901250	negative regulation of lung goblet cell differentiation	Foxp1	IGI	MGI:MGI:1921373	Mouse	PMID:22675208
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IDA		Mouse	MGI:MGI:2137760\|PMID:11358962
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IDA		Mouse	PMID:20713518
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IDA		Mouse	PMID:14701752
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IDA		Mouse	PMID:17428829
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IGI	MGI:MGI:1337080	Mouse	PMID:18347093
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp1	IMP		Rat	PMID:21606195\|RGD:11561924
Biological Process	GO:0036035	osteoclast development	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0030316	osteoclast differentiation	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0050861	positive regulation of B cell receptor signaling pathway	FOXP1	IMP		Human	PMID:30111844
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxp1	IMP		Mouse	MGI:MGI:4849611\|PMID:20711475
Biological Process	GO:0010595	positive regulation of endothelial cell migration	FOXP1	IMP		Human	PMID:24023716
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	Foxp1	IMP		Rat	PMID:26333362\|RGD:11561912
Biological Process	GO:0002639	positive regulation of immunoglobulin production	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:16819554
Biological Process	GO:0032745	positive regulation of interleukin-21 production	Foxp1	IDA		Mouse	MGI:MGI:5607369\|PMID:24859450
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	FOXP1	IMP		Human	PMID:24023716
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxp1	IMP	MGI:MGI:4829787	Mouse	PMID:20713518
Biological Process	GO:0002329	pre-B cell differentiation	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:16819554
Biological Process	GO:0098900	regulation of action potential	Foxp1	IMP	MGI:MGI:3711150	Mouse	PMID:26494785
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	Foxp1	IMP		Mouse	PMID:20713518
Biological Process	GO:0060043	regulation of cardiac muscle cell proliferation	Foxp1	IGI	MGI:MGI:1891346	Mouse	PMID:20713518
Biological Process	GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:1900424	regulation of defense response to bacterium	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:1901509	regulation of endothelial tube morphogenesis	FOXP1	IMP		Human	PMID:24023716
Biological Process	GO:0010468	regulation of gene expression	FOXP1	IMP		Human	PMID:28218735
Biological Process	GO:0050727	regulation of inflammatory response	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0032651	regulation of interleukin-1 beta production	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0032655	regulation of interleukin-12 production	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:1901249	regulation of lung goblet cell differentiation	Foxp1	IGI	MGI:MGI:1921373	Mouse	PMID:22675208
Biological Process	GO:1901249	regulation of lung goblet cell differentiation	Foxp1	IGI	MGI:MGI:1344405	Mouse	PMID:22675208
Biological Process	GO:1901256	regulation of macrophage colony-stimulating factor production	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0045655	regulation of monocyte differentiation	FOXP1	IDA		Human	PMID:15286807
Biological Process	GO:0032680	regulation of tumor necrosis factor production	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0032496	response to lipopolysaccharide	FOXP1	IDA		Human	PMID:18799727
Biological Process	GO:0033574	response to testosterone	Foxp1	IEP		Rat	PMID:25247470\|RGD:11536003
Biological Process	GO:0007519	skeletal muscle tissue development	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:0048745	smooth muscle tissue development	Foxp1	IGI	MGI:MGI:2148705	Mouse	PMID:17428829
Biological Process	GO:0021756	striatum development	Foxp1	IEP		Rat	PMID:12815709\|RGD:11536004
Biological Process	GO:0061470	T follicular helper cell differentiation	Foxp1	IDA		Mouse	MGI:MGI:5607369\|PMID:24859450
Biological Process	GO:0006366	transcription by RNA polymerase II	Foxp1	IMP	MGI:MGI:4829787	Mouse	PMID:20713518
Biological Process	GO:0021517	ventral spinal cord development	Foxp1	IEP		Mouse	MGI:MGI:4849611\|PMID:20711475

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.