Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Foxp3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes FOXP3
- Mouse genes Foxp3
- Rat genes Foxp3
- Zfish genes foxp3a,foxp3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	FOXP3	IMP		Human	PMID:21458306
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXP3	IDA		Human	PMID:11483607
Molecular Function	GO:0003700	DNA-binding transcription factor activity	FOXP3	IDA		Human	PMID:32644293
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Foxp3	IDA		Mouse	PMID:17028180
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	Foxp3	IDA		Mouse	PMID:17028180
Molecular Function	GO:0035035	histone acetyltransferase binding	FOXP3	IPI	UniProtKB:Q92993	Human	PMID:17360565
Molecular Function	GO:0042826	histone deacetylase binding	FOXP3	IPI	UniProtKB:Q8WUI4	Human	PMID:17360565
Molecular Function	GO:0042826	histone deacetylase binding	FOXP3	IPI	UniProtKB:Q9UKV0	Human	PMID:17360565
Molecular Function	GO:0042802	identical protein binding	Foxp3	IPI	PR:Q99JB6	Mouse	PMID:16769892
Molecular Function	GO:0051525	NFAT protein binding	FOXP3	IPI	UniProtKB:Q13469	Human	PMID:16873067
Molecular Function	GO:0051525	NFAT protein binding	FOXP3	IPI	UniProtKB:Q13469	Human	PMID:21458306
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q09472	Human	PMID:16652169
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q01196	Human	PMID:17377532
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P35398-4	Human	PMID:18354202
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P51449	Human	PMID:18368049
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q9UKT9	Human	PMID:20676092
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P62136	Human	PMID:23396208
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q8TF47-3	Human	PMID:23543754
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q9UNE7	Human	PMID:23973223
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:O14737	Human	PMID:24012345
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P86479	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P86478	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q93062-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P86478	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q93062	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P86478	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q93062	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P53539	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P86480	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q8IUC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:Q9H0E7	Human	PMID:32644293
Molecular Function	GO:0005515	protein binding	FOXP3	IPI	UniProtKB:P0DTD1:PRO_0000449621	Human	PMID:34019767
Molecular Function	GO:0005515	protein binding	Foxp3	IPI	UniProtKB:Q8C2S0	Mouse	MGI:MGI:6478069\|PMID:32644293
Molecular Function	GO:0005515	protein binding	Foxp3	IPI	UniProtKB:Q03347	Mouse	MGI:MGI:3710039\|PMID:17377532
Molecular Function	GO:0005515	protein binding	Foxp3	IPI	UniProtKB:Q13469\|UniProtKB:Q13761\|UniProtKB:Q13950	Mouse	MGI:MGI:3710039\|PMID:17377532
Molecular Function	GO:0005515	protein binding	Foxp3	IPI	UniProtKB:P51450	Mouse	MGI:MGI:3795336\|PMID:18368049
Molecular Function	GO:0042803	protein homodimerization activity	FOXP3	IPI	UniProtKB:Q9BZS1	Human	PMID:16920951
Molecular Function	GO:0042803	protein homodimerization activity	FOXP3	IDA		Human	PMID:21458306
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Foxp3	IDA		Mouse	MGI:MGI:3710039\|PMID:17377532
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXP3	IDA		Human	PMID:11483607
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXP3	IDA		Human	PMID:16873067
Molecular Function	GO:0043565	sequence-specific DNA binding	FOXP3	IDA		Human	PMID:19276356
Molecular Function	GO:0043565	sequence-specific DNA binding	Foxp3	IDA		Mouse	PMID:17028180
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FOXP3	IDA		Human	PMID:28473536
Molecular Function	GO:0003714	transcription corepressor activity	Foxp3	IDA		Mouse	PMID:15790681
Cellular Component	GO:0005737	cytoplasm	FOXP3	IDA		Human	PMID:22678915
Cellular Component	GO:0005737	cytoplasm	Foxp3	IDA		Mouse	PMID:17028180
Cellular Component	GO:0005622	intracellular anatomical structure	Foxp3	IDA		Mouse	PMID:19015308
Cellular Component	GO:0005654	nucleoplasm	FOXP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:32644293
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:11483607
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:16873067
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:16920951
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:22678915
Cellular Component	GO:0005634	nucleus	FOXP3	IDA		Human	PMID:24012345
Cellular Component	GO:0005634	nucleus	Foxp3	IDA		Mouse	MGI:MGI:3795336\|PMID:18368049
Cellular Component	GO:0005634	nucleus	Foxp3	IDA		Mouse	MGI:MGI:3710039\|PMID:17377532
Cellular Component	GO:0005634	nucleus	Foxp3	IDA		Mouse	PMID:17028180
Cellular Component	GO:0005634	nucleus	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0046633	alpha-beta T cell proliferation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0001782	B cell homeostasis	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:10072494
Biological Process	GO:0043367	CD4-positive, alpha-beta T cell differentiation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0035739	CD4-positive, alpha-beta T cell proliferation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:18573908
Biological Process	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16301745
Biological Process	GO:0006338	chromatin remodeling	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0001816	cytokine production	Foxp3	IDA		Mouse	PMID:15790681
Biological Process	GO:0001816	cytokine production	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:10072494
Biological Process	GO:0001816	cytokine production	Foxp3	IGI	MGI:MGI:88335	Mouse	PMID:7930593
Biological Process	GO:0001816	cytokine production	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:7930593
Biological Process	GO:0001816	cytokine production	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:8566060
Biological Process	GO:0006351	DNA-templated transcription	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0014045	establishment of endothelial blood-brain barrier	Foxp3	IEP		Rat	PMID:31027862\|RGD:38549575
Biological Process	GO:0010467	gene expression	Foxp3	IMP		Mouse	PMID:28396406
Biological Process	GO:0033080	immature T cell proliferation in thymus	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16230479
Biological Process	GO:0006954	inflammatory response	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16203996
Biological Process	GO:0032613	interleukin-10 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032623	interleukin-2 production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032623	interleukin-2 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032633	interleukin-4 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032633	interleukin-4 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032634	interleukin-5 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032634	interleukin-5 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032635	interleukin-6 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0048289	isotype switching to IgE isotypes	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0046651	lymphocyte proliferation	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0046651	lymphocyte proliferation	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:16227984
Biological Process	GO:0002262	myeloid cell homeostasis	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:10072494
Biological Process	GO:0046642	negative regulation of alpha-beta T cell proliferation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0008285	negative regulation of cell population proliferation	FOXP3	IDA		Human	PMID:15652505
Biological Process	GO:0002677	negative regulation of chronic inflammatory response	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0002677	negative regulation of chronic inflammatory response	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032792	negative regulation of CREB transcription factor activity	FOXP3	IDA		Human	PMID:16652169
Biological Process	GO:0001818	negative regulation of cytokine production	FOXP3	IDA		Human	PMID:11483607
Biological Process	GO:0050687	negative regulation of defense response to virus	Foxp3	IMP		Rat	PMID:17878294\|RGD:2325989
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	FOXP3	IDA		Human	PMID:16873067
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IDA		Human	PMID:11483607
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IDA		Human	PMID:16920951
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IDA		Human	PMID:17360565
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IMP		Human	PMID:21458306
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IDA		Human	PMID:22678915
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Foxp3	IDA		Mouse	PMID:15100250
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Foxp3	IDA		Mouse	PMID:15790681
Biological Process	GO:0010629	negative regulation of gene expression	Foxp3	IDA		Mouse	PMID:24501220
Biological Process	GO:0031064	negative regulation of histone deacetylation	FOXP3	IGI	UniProtKB:P56524	Human	PMID:19276356
Biological Process	GO:0050777	negative regulation of immune response	FOXP3	IDA		Human	PMID:15652505
Biological Process	GO:0050728	negative regulation of inflammatory response	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16203996
Biological Process	GO:0032693	negative regulation of interleukin-10 production	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0032693	negative regulation of interleukin-10 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032700	negative regulation of interleukin-17 production	FOXP3	IMP		Human	PMID:18368049
Biological Process	GO:0032700	negative regulation of interleukin-17 production	Foxp3	IMP		Mouse	MGI:MGI:3795336\|PMID:18368049
Biological Process	GO:0032703	negative regulation of interleukin-2 production	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0032703	negative regulation of interleukin-2 production	FOXP3	IMP		Human	PMID:16873067
Biological Process	GO:0032703	negative regulation of interleukin-2 production	FOXP3	IDA		Human	PMID:17360565
Biological Process	GO:0032703	negative regulation of interleukin-2 production	FOXP3	IDA		Human	PMID:17377532
Biological Process	GO:0032703	negative regulation of interleukin-2 production	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Foxp3	IMP		Mouse	MGI:MGI:3795336\|PMID:18368049
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Foxp3	IDA		Mouse	MGI:MGI:3710039\|PMID:17377532
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032703	negative regulation of interleukin-2 production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032713	negative regulation of interleukin-4 production	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0032713	negative regulation of interleukin-4 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032713	negative regulation of interleukin-4 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032714	negative regulation of interleukin-5 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032714	negative regulation of interleukin-5 production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032715	negative regulation of interleukin-6 production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0048294	negative regulation of isotype switching to IgE isotypes	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0050672	negative regulation of lymphocyte proliferation	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0050672	negative regulation of lymphocyte proliferation	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:16227984
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	FOXP3	IDA		Human	PMID:16652169
Biological Process	GO:0002725	negative regulation of T cell cytokine production	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0002725	negative regulation of T cell cytokine production	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0042130	negative regulation of T cell proliferation	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0042130	negative regulation of T cell proliferation	FOXP3	IMP		Human	PMID:21458306
Biological Process	GO:0042130	negative regulation of T cell proliferation	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0042130	negative regulation of T cell proliferation	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0042130	negative regulation of T cell proliferation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16203996
Biological Process	GO:2000320	negative regulation of T-helper 17 cell differentiation	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp3	IDA		Mouse	PMID:16230479
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16230479
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032689	negative regulation of type II interferon production	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0032689	negative regulation of type II interferon production	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0032689	negative regulation of type II interferon production	Foxp3	IDA		Mouse	MGI:MGI:3710039\|PMID:17377532
Biological Process	GO:0032689	negative regulation of type II interferon production	Foxp3	IMP		Mouse	MGI:MGI:3795336\|PMID:18368049
Biological Process	GO:0032689	negative regulation of type II interferon production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032689	negative regulation of type II interferon production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032689	negative regulation of type II interferon production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16301745
Biological Process	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:12612578
Biological Process	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:18573908
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXP3	IMP		Human	PMID:19276356
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXP3	IMP		Human	PMID:21458306
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXP3	IMP		Human	PMID:23169781
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxp3	IMP		Mouse	MGI:MGI:3710039\|PMID:17377532
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0010628	positive regulation of gene expression	Foxp3	IDA		Mouse	PMID:20706986
Biological Process	GO:0010628	positive regulation of gene expression	Foxp3	IDA		Mouse	PMID:24501220
Biological Process	GO:0035066	positive regulation of histone acetylation	FOXP3	IMP		Human	PMID:19276356
Biological Process	GO:0033092	positive regulation of immature T cell proliferation in thymus	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16230479
Biological Process	GO:0032753	positive regulation of interleukin-4 production	Foxp3	IMP		Mouse	PMID:20944002
Biological Process	GO:0002851	positive regulation of peripheral T cell tolerance induction	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:16532000
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	FOXP3	IDA		Human	PMID:30513302
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:12522256
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:15100250
Biological Process	GO:0045591	positive regulation of regulatory T cell differentiation	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:15780990
Biological Process	GO:0002669	positive regulation of T cell anergy	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0002666	positive regulation of T cell tolerance induction	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXP3	IMP		Human	PMID:19276356
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0032914	positive regulation of transforming growth factor beta1 production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0002637	regulation of immunoglobulin production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0048302	regulation of isotype switching to IgG isotypes	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0002667	regulation of T cell anergy	Foxp3	IMP		Mouse	MGI:MGI:3710039\|PMID:17377532
Biological Process	GO:0042129	regulation of T cell proliferation	foxp3a	IMP	ZFIN:ZDB-GENO-171106-5	Zfish	PMID:28365195
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Foxp3	IGI	MGI:MGI:95663	Mouse	PMID:18997793
Biological Process	GO:0045066	regulatory T cell differentiation	FOXP3	IDA		Human	PMID:32644293
Biological Process	GO:0045066	regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0045066	regulatory T cell differentiation	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032496	response to lipopolysaccharide	Foxp3	IEP		Rat	PMID:19998507\|RGD:38455980
Biological Process	GO:0009314	response to radiation	Foxp3	IEP		Rat	PMID:30328796\|RGD:38549363
Biological Process	GO:1901355	response to rapamycin	Foxp3	IEP		Rat	PMID:24507682\|RGD:38599141
Biological Process	GO:0009615	response to virus	FOXP3	IEP		Human	PMID:20583921
Biological Process	GO:0042110	T cell activation	FOXP3	IDA		Human	PMID:15466453
Biological Process	GO:0042110	T cell activation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:10072494
Biological Process	GO:0002870	T cell anergy	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0002456	T cell mediated immunity	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:11714795
Biological Process	GO:0042098	T cell proliferation	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0042098	T cell proliferation	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16203996
Biological Process	GO:0050852	T cell receptor signaling pathway	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:11265635
Biological Process	GO:0050852	T cell receptor signaling pathway	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:10072494
Biological Process	GO:0002517	T cell tolerance induction	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0002507	tolerance induction	Foxp3	IDA		Mouse	PMID:15809349
Biological Process	GO:0002513	tolerance induction to self antigen	Foxp3	IMP	MGI:MGI:2654936	Mouse	PMID:15780990
Biological Process	GO:0006366	transcription by RNA polymerase II	Foxp3	IMP	MGI:MGI:1857034	Mouse	PMID:16945588
Biological Process	GO:0006366	transcription by RNA polymerase II	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032905	transforming growth factor beta1 production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032640	tumor necrosis factor production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384
Biological Process	GO:0032609	type II interferon production	Foxp3	IDA		Mouse	PMID:16769892
Biological Process	GO:0032609	type II interferon production	Foxp3	IDA		Mouse	PMID:17028180
Biological Process	GO:0032609	type II interferon production	Foxp3	IMP	MGI:MGI:3696705	Mouse	PMID:16275384

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.