Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FPGS
  • Mouse genes Fpgs
  • Rat genes Fpgs
  • Zfish genes fpgs
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fpgs

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	FPGS	IDA		Human	PMID:3619447
Molecular Function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity	Fpgs	IDA		Rat	PMID:6892914|RGD:2315105
Cellular Component	GO:0005739	mitochondrion	Fpgs	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Fpgs	HDA		Mouse	PMID:14651853
Biological Process	GO:0031100	animal organ regeneration	Fpgs	IEP		Rat	PMID:3654111|RGD:2315103
Biological Process	GO:0007420	brain development	Fpgs	IEP		Rat	PMID:1435744|RGD:2315102
Biological Process	GO:0006760	folic acid-containing compound metabolic process	FPGS	IDA		Human	PMID:3619447
Biological Process	GO:0006536	glutamate metabolic process	FPGS	IDA		Human	PMID:3619447
Biological Process	GO:0001889	liver development	Fpgs	IEP		Rat	PMID:1435744|RGD:2315102
Biological Process	GO:0046901	tetrahydrofolylpolyglutamate biosynthetic process	FPGS	IDA		Human	PMID:3619447

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern