Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FRMD4B
  • Mouse genes Frmd4b
  • Rat genes Frmd4b
  • Zfish genes frmd4ba,frmd4bb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frmd4b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Frmd4b	IPI	PR:O08967	Mouse	PMID:11445584
Cellular Component	GO:0005912	adherens junction	Frmd4b	IDA		Mouse	MGI:MGI:4420836|PMID:20080746
Cellular Component	GO:0005923	bicellular tight junction	Frmd4b	IDA		Mouse	MGI:MGI:4420836|PMID:20080746
Cellular Component	GO:0005737	cytoplasm	Frmd4b	IDA		Mouse	PMID:11445584
Cellular Component	GO:0005615	extracellular space	FRMD4B	HDA		Human	PMID:23580065
Cellular Component	GO:0001726	ruffle	Frmd4b	IPI	PR:O08967	Mouse	PMID:11445584
Biological Process	GO:0090162	establishment of epithelial cell polarity	Frmd4b	IGI	MGI:MGI:1919850	Mouse	PMID:20080746

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern