Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FRMD8,FRMD8P1
  • Mouse genes Frmd8
  • Rat genes Frmd8
  • Zfish genes frmd8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Frmd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q96HH9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q6PJF5|UniProtKB:Q96CC6	Human	PMID:29897333
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:P78536|UniProtKB:Q6PJF5|UniProtKB:Q80WQ6|UniProtKB:Q96CC6	Human	PMID:29897336
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q12809-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q6S9Z5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q969F0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q96HH9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q9H400	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FRMD8	IPI	UniProtKB:Q9NWS9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Frmd8	IPI	PR:Q96CC6	Mouse	PMID:29897333
Molecular Function	GO:0005515	protein binding	Frmd8	IPI	PR:Q80WQ6	Mouse	PMID:29897333
Cellular Component	GO:0034451	centriolar satellite	FRMD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	FRMD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	FRMD8	IDA		Human	PMID:29897333
Cellular Component	GO:0005654	nucleoplasm	FRMD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FRMD8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	FRMD8	IDA		Human	PMID:29897333
Biological Process	GO:0009952	anterior/posterior pattern specification	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3	Zfish	PMID:19572019
Biological Process	GO:0009952	anterior/posterior pattern specification	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4	Zfish	PMID:19572019
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3	Zfish	PMID:19572019
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4	Zfish	PMID:19572019
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	FRMD8	IDA		Human	PMID:29897333
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	FRMD8	IMP		Human	PMID:29897336
Biological Process	GO:0072659	protein localization to plasma membrane	Frmd8	IMP	MGI:MGI:6258447	Mouse	PMID:29897333
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4	Zfish	PMID:19572019
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	frmd8	IGI	ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3	Zfish	PMID:19572019

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern